EU H2020 Project "IMPLANTALIVE (Explore the potentialities of living implants for medical devices)": description, partecipants, costs and EC-fundings

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IMPLANTaLive project word cloud

Explore the words cloud of the IMPLANTaLive project. It provides you a very rough idea of what is the project "IMPLANTaLive" about.

disrupting biocoating provides fail sick routes surfaces gras ie tissue ligament inherently disturbs coatings repair coating influence biological societal performance cell releasing advantages inferior surface conventional leave opportunity public conditioning enhances quality polymeric bidirectionality implantation business loops infections vivo actively function injured cells suitable healthy metal bacteria financing health implantalive interacting economic causing responsive patient combined technologies stimuli adverse endothelial surroundings reactions pathogenic mostly host approved suitably site innovative introduction express dynamic dynamics majority tendon industry companies implant caused easily hence market reconstruction body static markets attractive proper adhesion science bound cellular biocoatings medical restoring fda offers vascular membrane status living expressed stimulate poor proteins feedback

Project "IMPLANTaLive" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITEIT TWENTE Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB website: www.utwente.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Total cost	150˙000 €
EC max contribution	150˙000 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2016-PoC
Funding Scheme	ERC-POC
Starting year	2017
Duration (year-month-day)	from 2017-04-01 to 2018-09-30

#	participants	country	role	EC contrib. [€]
1	UNIVERSITEIT TWENTE	NL (ENSCHEDE)	coordinator	150˙000.00

UNIVERSITEIT TWENTE

NL (ENSCHEDE)

coordinator

150˙000.00

Project objective

IMPLANTaLive coating technology provides an exciting business opportunity. IMPLANTaLive offers unique advantages of societal and economic importance such as public health and sick leave.

Living, dynamic coatings for medical devices, ie. coatings with proper cell response upon implantation, are attractive for restoring body function. Conventional implant coatings are of inferior quality and therefore the majority, if not all, biocoatings fail in suitably interacting with host tissue. This poor performance of existing biocoating technologies is mostly caused by inherently static properties of surface coating, which disturbs the inherently dynamics between cells and surroundings, disrupting healthy tissue response and eventually causing adverse reactions like infections. Living coatings are produced by an innovative one step pre-conditioning of FDA approved polymeric and metal surfaces. Living non-pathogenic bacteria with GRAS status are suitable for in-vivo use, which provide medical devices with dynamic and responsive characteristics.

Dynamic IMPLANTaLive coatings provide bidirectionality, ie. the ability to process biological stimuli by cellular control feedback loops and hence influence cellular and tissue characteristics and responses. This greatly enhances the application potential as the living coating can be easily tailored to the specific needs of a patient. IMPLANTaLive coatings can actively stimulate the reconstruction or injured site by releasing specific growth factors (relevant for ligament and tendon repair) or express membrane bound endothelial cell specific adhesion proteins (relevant for vascular devices).

A business case will be developed for IMPLANTaLive covering different markets and routes for market introduction. Results of market analysis and financing needs will be combined with science-based technology comparison and used for discussions with potential industry partners. Several companies have already expressed interest in IMPLANTaLive.

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The information about "IMPLANTALIVE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)