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IMPLANTaLive SIGNED

Explore the potentialities of living implants for medical devices

Total Cost €

0

EC-Contrib. €

0

Partnership

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 IMPLANTaLive project word cloud

Explore the words cloud of the IMPLANTaLive project. It provides you a very rough idea of what is the project "IMPLANTaLive" about.

disrupting    biocoating    provides    fail    sick    routes    surfaces    gras    ie    tissue    ligament    inherently    disturbs    coatings    repair    coating    influence    biological    societal    performance    cell    releasing    advantages    inferior    surface    conventional    leave    opportunity    public    conditioning    enhances    quality    polymeric    bidirectionality    implantation    business    loops    infections    vivo    actively    function    injured    cells    suitable    healthy    metal    bacteria    financing    health    implantalive    interacting    economic    causing    responsive    patient    combined    technologies    stimuli    adverse    endothelial    surroundings    reactions    pathogenic    mostly    host    approved    suitably    site    innovative    introduction    express    dynamic    dynamics    majority    tendon    industry    companies    implant    caused    easily    hence    market    reconstruction    body    static    markets    attractive    proper    adhesion    science    bound    cellular    biocoatings    medical    restoring    fda    offers    vascular    membrane    status    living    expressed    stimulate    poor    proteins    feedback   

Project "IMPLANTaLive" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-04-01   to  2018-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 150˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

IMPLANTaLive coating technology provides an exciting business opportunity. IMPLANTaLive offers unique advantages of societal and economic importance such as public health and sick leave.

Living, dynamic coatings for medical devices, ie. coatings with proper cell response upon implantation, are attractive for restoring body function. Conventional implant coatings are of inferior quality and therefore the majority, if not all, biocoatings fail in suitably interacting with host tissue. This poor performance of existing biocoating technologies is mostly caused by inherently static properties of surface coating, which disturbs the inherently dynamics between cells and surroundings, disrupting healthy tissue response and eventually causing adverse reactions like infections. Living coatings are produced by an innovative one step pre-conditioning of FDA approved polymeric and metal surfaces. Living non-pathogenic bacteria with GRAS status are suitable for in-vivo use, which provide medical devices with dynamic and responsive characteristics.

Dynamic IMPLANTaLive coatings provide bidirectionality, ie. the ability to process biological stimuli by cellular control feedback loops and hence influence cellular and tissue characteristics and responses. This greatly enhances the application potential as the living coating can be easily tailored to the specific needs of a patient. IMPLANTaLive coatings can actively stimulate the reconstruction or injured site by releasing specific growth factors (relevant for ligament and tendon repair) or express membrane bound endothelial cell specific adhesion proteins (relevant for vascular devices).

A business case will be developed for IMPLANTaLive covering different markets and routes for market introduction. Results of market analysis and financing needs will be combined with science-based technology comparison and used for discussions with potential industry partners. Several companies have already expressed interest in IMPLANTaLive.

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The information about "IMPLANTALIVE" are provided by the European Opendata Portal: CORDIS opendata.

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