Opendata, web and dolomites


Explore the potentialities of living implants for medical devices

Total Cost €


EC-Contrib. €






 IMPLANTaLive project word cloud

Explore the words cloud of the IMPLANTaLive project. It provides you a very rough idea of what is the project "IMPLANTaLive" about.

polymeric    repair    endothelial    healthy    advantages    mostly    technologies    patient    suitably    dynamic    disturbs    implant    biocoating    actively    financing    medical    proper    implantation    ie    cellular    status    biological    proteins    injured    easily    fda    dynamics    opportunity    bacteria    living    conventional    quality    business    loops    vivo    pathogenic    tendon    innovative    coating    coatings    inherently    ligament    provides    gras    stimuli    health    public    disrupting    surface    body    responsive    science    static    expressed    companies    cells    vascular    infections    majority    introduction    offers    suitable    interacting    adverse    causing    sick    reactions    hence    function    bidirectionality    caused    societal    conditioning    site    releasing    membrane    fail    combined    leave    enhances    adhesion    express    markets    industry    tissue    economic    performance    surroundings    inferior    stimulate    host    cell    influence    routes    metal    restoring    market    approved    attractive    biocoatings    poor    feedback    implantalive    surfaces    reconstruction    bound   

Project "IMPLANTaLive" data sheet

The following table provides information about the project.


Organization address
postcode: 7522 NB

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-04-01   to  2018-09-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 150˙000.00


 Project objective

IMPLANTaLive coating technology provides an exciting business opportunity. IMPLANTaLive offers unique advantages of societal and economic importance such as public health and sick leave.

Living, dynamic coatings for medical devices, ie. coatings with proper cell response upon implantation, are attractive for restoring body function. Conventional implant coatings are of inferior quality and therefore the majority, if not all, biocoatings fail in suitably interacting with host tissue. This poor performance of existing biocoating technologies is mostly caused by inherently static properties of surface coating, which disturbs the inherently dynamics between cells and surroundings, disrupting healthy tissue response and eventually causing adverse reactions like infections. Living coatings are produced by an innovative one step pre-conditioning of FDA approved polymeric and metal surfaces. Living non-pathogenic bacteria with GRAS status are suitable for in-vivo use, which provide medical devices with dynamic and responsive characteristics.

Dynamic IMPLANTaLive coatings provide bidirectionality, ie. the ability to process biological stimuli by cellular control feedback loops and hence influence cellular and tissue characteristics and responses. This greatly enhances the application potential as the living coating can be easily tailored to the specific needs of a patient. IMPLANTaLive coatings can actively stimulate the reconstruction or injured site by releasing specific growth factors (relevant for ligament and tendon repair) or express membrane bound endothelial cell specific adhesion proteins (relevant for vascular devices).

A business case will be developed for IMPLANTaLive covering different markets and routes for market introduction. Results of market analysis and financing needs will be combined with science-based technology comparison and used for discussions with potential industry partners. Several companies have already expressed interest in IMPLANTaLive.

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The information about "IMPLANTALIVE" are provided by the European Opendata Portal: CORDIS opendata.

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