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IMPLANTaLive SIGNED

Explore the potentialities of living implants for medical devices

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 IMPLANTaLive project word cloud

Explore the words cloud of the IMPLANTaLive project. It provides you a very rough idea of what is the project "IMPLANTaLive" about.

expressed    function    public    easily    dynamics    loops    leave    quality    ie    combined    cells    status    routes    stimuli    implantalive    financing    dynamic    surfaces    advantages    reactions    injured    attractive    economic    inherently    suitable    innovative    conditioning    market    hence    opportunity    feedback    bound    approved    bidirectionality    healthy    companies    adhesion    membrane    societal    causing    vivo    surroundings    releasing    actively    medical    cellular    reconstruction    coating    ligament    majority    inferior    polymeric    metal    pathogenic    poor    cell    stimulate    gras    enhances    tendon    living    business    coatings    sick    patient    bacteria    markets    endothelial    introduction    express    biocoating    implantation    static    surface    suitably    disturbs    repair    host    performance    restoring    science    fda    industry    proteins    interacting    biological    offers    provides    responsive    health    fail    caused    mostly    disrupting    implant    site    tissue    influence    proper    adverse    body    biocoatings    infections    conventional    technologies    vascular   

Project "IMPLANTaLive" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-04-01   to  2018-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 150˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

IMPLANTaLive coating technology provides an exciting business opportunity. IMPLANTaLive offers unique advantages of societal and economic importance such as public health and sick leave.

Living, dynamic coatings for medical devices, ie. coatings with proper cell response upon implantation, are attractive for restoring body function. Conventional implant coatings are of inferior quality and therefore the majority, if not all, biocoatings fail in suitably interacting with host tissue. This poor performance of existing biocoating technologies is mostly caused by inherently static properties of surface coating, which disturbs the inherently dynamics between cells and surroundings, disrupting healthy tissue response and eventually causing adverse reactions like infections. Living coatings are produced by an innovative one step pre-conditioning of FDA approved polymeric and metal surfaces. Living non-pathogenic bacteria with GRAS status are suitable for in-vivo use, which provide medical devices with dynamic and responsive characteristics.

Dynamic IMPLANTaLive coatings provide bidirectionality, ie. the ability to process biological stimuli by cellular control feedback loops and hence influence cellular and tissue characteristics and responses. This greatly enhances the application potential as the living coating can be easily tailored to the specific needs of a patient. IMPLANTaLive coatings can actively stimulate the reconstruction or injured site by releasing specific growth factors (relevant for ligament and tendon repair) or express membrane bound endothelial cell specific adhesion proteins (relevant for vascular devices).

A business case will be developed for IMPLANTaLive covering different markets and routes for market introduction. Results of market analysis and financing needs will be combined with science-based technology comparison and used for discussions with potential industry partners. Several companies have already expressed interest in IMPLANTaLive.

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The information about "IMPLANTALIVE" are provided by the European Opendata Portal: CORDIS opendata.

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