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Total Cost €


EC-Contrib. €






 IN-PLANTO_CUES project word cloud

Explore the words cloud of the IN-PLANTO_CUES project. It provides you a very rough idea of what is the project "IN-PLANTO_CUES" about.

chloroplasts    organelles    signal    vib    phosphoadenosine    signaling    impose    initiator    drought    oxidative    multiple    coordinated    biosynthetic    fundamental    negatively    enigmatic    opportunity    homeostasis    sal1    collectively    chloroplast    cells    redox    mechanisms    signals    talk    function    understand    integration    tolerance    conversely    plant    mitochondria    temperature    apparently    adjustment    interaction    integrate    model    localized    pap    linked    components    death    coordinate    light    outcomes    scales    trigger    occurs    intriguing    programmed    first    invoke    pnas    phosphate    anac013    cellular    ing    questions    mechanism    consisting    harmonic    cell    metabolism    acclimation    enhanced    stress    transcription    combine    mobile    transducer    extremes    environmental    hosts    mitochondrial    levels    crosstalk    physiological    regulated    hinting    reveal    nucleus    exemplar    cross    discordant    sensing    enzyme   

Project "IN-PLANTO_CUES" data sheet

The following table provides information about the project.


Organization address
postcode: 9052

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 172˙800 €
 EC max contribution 172˙800 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-03-12   to  2020-03-11


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    VIB VZW BE (ZWIJNAARDE - GENT) coordinator 172˙800.00


 Project objective

Environmental challenges such as drought, temperature and light extremes can impose oxidative stress in multiple organelles, thus negatively affecting the function of plant cells. Both chloroplasts and mitochondria can invoke signaling pathways to the nucleus that trigger stress responses and adjustment of cellular homeostasis, resulting in physiological outcomes such as enhanced stress tolerance, or conversely programmed cell death. These pathways include the 3'-phosphoadenosine 5'-phosphate (PAP)-SAL1 pathway for chloroplasts and the ANAC013 mobile transcription factor for mitochondria. However, the mechanisms by which plant cells coordinate different signals from chloroplasts and mitochondria for whole-cell acclimation to oxidative stress are still enigmatic. Whether there is any cross-talk between chloroplast and mitochondrial signaling is also intriguing. My project will investigate these fundamental questions using an exemplar model system consisting of three components that combine my research with the Hosts’. The first goal is to take my PNAS findings that SAL1 is a redox-regulated initiator of chloroplast signaling and determine if a similar mechanism occurs in the mitochondria, where SAL1 is also localized. This would reveal how two distinct organelles can integrate oxidative stress sensing and response by using the same pathway. Second, the interaction between SAL1-redox sensing and the mitochondrial signaling transducer ANAC013 will be investigated to understand integration between these two apparently distinct pathways. Third, ANAC013 targets a biosynthetic enzyme for PAP hinting at crosstalk between mitochondrial and chloroplast signaling at the level of signal metabolism. Thus, my research on SAL1-PAP and VIB’s on ANAC013 collectively present a unique opportunity to reveal how the two pathways are linked at different levels enabling cellular signaling to be coordinated across scales to facilitate a harmonic, not discordant acclimation response.

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The information about "IN-PLANTO_CUES" are provided by the European Opendata Portal: CORDIS opendata.

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