Opendata, web and dolomites
H2020 projects about "transcription"
The page lists 317 projects related to the topic "transcription".
| # | |||
|---|---|---|---|
| 1 | REPROWORM | Safeguarding Cell Identities: Mechanisms Counteracting Cell Fate Reprogramming | 2015 |
| 2 | ChromArch | Single Molecule Mechanisms of Spatio-Temporal Chromatin Architecture | 2015 |
| 3 | SCORA | A systematic characterization of human regulatory architectures and their determinants of regulatory activity | 2015 |
| 4 | SILENCE | Mechanisms of Gene Silencing by the Glucocorticoid Receptor | 2015 |
| 5 | G4DSB | G-quadruplex DNA Structures and Genome Stability | 2015 |
| 6 | PRCTOERC | Novel Regulatory Principles of Polycomb Repressive Complex 2 | 2015 |
| 7 | Medulloblastoma | Molecularly defined models of human childhood brain tumors | 2015 |
| 8 | Chromatin3D | Chromatin Dynamics in Development and Disease | 2015 |
| 9 | ZENCODE-ITN | Computational and functional annotation of genomic elements during development of the model vertebrate zebrafish | 2015 |
| 10 | NICHOID | Mechanobiology of nuclear import of transcription factors modeled within a bioengineered stem cell niche. | 2015 |
| 11 | OTULINVIVO | The role of OTULIN and Met1-linked ubiquitin in immune signaling and host defense in vivo | 2015 |
| 12 | Human Rpc5 | RNA Polymerase III Rpc4/Rpc5 subcomplex and Selenocysteine tRNA transcription | 2015 |
| 13 | EpiNKT | Transcriptional and epigenetic control of innate-like T lymphocyte development | 2015 |
| 14 | Cdc42Adhere | Role of Cdc42 in cancer cell adhesion to endothelial cells and platelets | 2015 |
| 15 | fetISC | Characterizing drivers of intestinal tissue maturation in vitro and in vivo | 2016 |
| 16 | PERFECTION | Probing mechanisms of pathogen effector recognition by plant Resistance proteins to elevate defence gene activation | 2016 |
| 17 | RAGES | Molecular determination of Rif1-Associated Genomic Elements and their function in regulating genome activity and integrity | 2016 |
| 18 | INAME | Imaging nucleic acid metabolism in cells | 2016 |
| 19 | TEACHPOL | Freedom of Teaching and Political Control: The Case of Thomas Aquinas’ Assimilation in William of Peter Godin’s Lectura Thomasina (14th C.) | 2015 |
| 20 | SECOMAP | Sexual Commitment of Malaria Parasites: Investigation Into the Epigenetic Control of Plasmodium Gametocytogenesis | 2015 |
| 21 | DecipherBILU | Understanding functional mechanisms leading to the BILU syndrome | 2015 |
| 22 | miRTurnOver | Identifying genes involved in microRNA turnover in Arabidopsis | 2015 |
| 23 | NeuroUTR | Systematic investigation of the functional coupling between transcriptional and post-transcriptional regulatory interactions underlying tissue-specific 3'UTRs variability. | 2015 |
| 24 | 3D-ADAPT | Analysis of tridimensional changes caused by type 2 Diabetes-Associated varianTs | 2015 |
| 25 | REZONABLE | Regeneration and zonation by ZEB2 of Liver Endothelium | 2016 |
| 26 | EPIMAIZE | Understading the Maize Epigenome and its Role in Development | 2015 |
| 27 | EVOLPREG | Origination of novel gene regulatory networks in the evolution of mammalian pregnancy | 2016 |
| 28 | Tbet ILC JFN | The role of innate lymphoid cells in regulating intestinal inflammation | 2015 |
| 29 | miRNAs in TH2 cells | Role of extracellular miRNAs in T cell development, TH2 cell differentiation and TH2 cell-mediated effector function | 2015 |
| 30 | CACOHET | “Causes and consequences of pluripotency gene regulatory network member heterogeneity” | 2016 |
| 31 | PIOMES | Pbx proteins as pioneer factors promoting signal specificity in mesodermal differentiation | 2015 |
| 32 | ID4 | Role of Id4 in the adult subventricular zone of normal and injured brain | 2015 |
| 33 | RLOOP-AS | Interconnection between R-loops and co-transcriptional alternative splicing | 2015 |
| 34 | MoDATS | Model-based Data Analysis of Transcription and Splicing | 2016 |
| 35 | REBuILD | Exploring the role of TFEB in exosome biology and in novel approaches for treatment of lysosomal diseases | 2016 |
| 36 | SOX10mutants | Investigating genotype-phenotype correlations in SOX10 neurocristopathies | 2015 |
| 37 | DUALgRENP | A DUAL gRNA system for functional assessment of ENhancers in Pluripotency | 2016 |
| 38 | RiceStyle | Carpel evolution: a walk in the rice side | 2016 |
| 39 | 3Dconvert | The dynamics of the mammalian epigenome during transcription factor-induced cell fate conversion | 2015 |
| 40 | lincSAFARI | Sequence and Function Relationships in Long Intervening Noncoding RNAs | 2015 |
| 41 | TRANSFR-Q | Transcriptional RegulAtory Network controlling Strawberry Fruit Ripening and Quality | 2015 |
| 42 | Enhancer ID | Identification and functional characterization of mammalian enhancers and transcriptional co-factors during cellular signaling and cell fate transitions | 2015 |
| 43 | ER_disease | Defining hormonal cross-talk and the role of mutations in estrogen receptor positive breast cancer | 2015 |
| 44 | DoReMIR | Automatic music transcription of polyphonic audio | 2015 |
| 45 | ZF-MEL-CHEMBIO | Chemical Biology in Zebrafish: Drug-Leads and New Targets in the Melanocyte Lineage and Melanoma | 2015 |
| 46 | DevoTed_miR | MicroRNA determinants of the balance between effector and regulatory T cells in vivo | 2015 |
| 47 | DECOR | Dynamic assembly and exchange of RNA polymerase II CTD factors | 2015 |
| 48 | OlfSwitch | OlfSwitch: Neural circuit switches from molecules to behaviour | 2015 |
| 49 | Allelic Regulation | Revealing Allele-level Regulation and Dynamics using Single-cell Gene Expression Analyses | 2015 |
| 50 | PROMETHEUS | Novel Cells for Organ Repair | 2015 |
| 51 | CilDyn | Molecular analysis of the Hedgehog signal transduction complex in the primary cilium | 2015 |
| 52 | OxygenSensing | Molecular mechanisms of acute oxygen sensing. | 2015 |
| 53 | TARLOOP | R-loops as a major modulator of transcription-associated recombination and chromatin dynamics | 2015 |
| 54 | Novel asthma therapy | Biocompatible nanoparticles for T cell targeted siRNA delivery as novel asthma therapy | 2015 |
| 55 | Drug-Seq | Unravelling the Genomic Targets of Drugs Using High-Throughput Sequencing | 2015 |
| 56 | AUROMYC | N-Myc and Aurora A: From Protein Stability to Chromosome TopologyN-Myc and Aurora A: From Protein Stability to Chromosome TopologyMyc and Aurora A: From Protein Stability to Chromosome Topology | 2015 |
| 57 | PHOTONET-C4 | Characterising the Gene Regulatory Networks Governing Photosynthesis: From Basic Understanding to Targeted Engineering | 2015 |
| 58 | MASAM | New tools for key questions in plant development: using qualitative and quantitative proteomics for direct determination of the set of DNA and RNA-binding factors regulating single copy genes | 2015 |
| 59 | DeFiNER | Nucleotide Excision Repair: Decoding its Functional Role in Mammals | 2016 |
| 60 | ReaDMe | Readout of DNA methylation | 2016 |
| 61 | ImmunityByPairDesign | Design and redesign of a plant immune receptor complex | 2015 |
| 62 | PlasmoSilencing | Exoribonuclease-mediated degradation of nascent RNA in Malaria Parasites: A Novel Mechanism in Virulence Gene Silencing | 2015 |
| 63 | BacCellEpi | Bacterial, cellular and epigenetic factors that control enteropathogenicity | 2015 |
| 64 | XPRESS | Exploring mechanisms of gene repression and escape during X-chromosome inactivation | 2015 |
| 65 | READ | Recognition and Enrichment of Archival Documents | 2016 |
| 66 | SexSeed | Sexual Plant Reproduction – Seed formation | 2016 |
| 67 | ExpoSEED | Exploring the molecular control of seed yield in crops | 2016 |
| 68 | DynaMech | Linking Transcription Factor Binding Dynamics to Promoter Output | 2016 |
| 69 | RNAREG | Single molecule observation and manipulation of gene expression dynamics to dissect mechanisms of cell cycle entry | 2016 |
| 70 | ThDEFINE | Re(defining) CD4+ T Cell Identities One Cell at a Time | 2016 |
| 71 | CleverGenes | Novel Gene Therapy Based on the Activation of Endogenous Genes for the Treatment of Ischemia - Concepts of endogenetherapy, release of promoter pausing, promoter-targeted ncRNAs and nuclear RNAi | 2015 |
| 72 | RNAEPIGEN | Mechanisms of epigenetic inheritance by short RNAs | 2016 |
| 73 | IMMUNE-EXPRESS | Proteasome-Mediated Gene Expression in Plant Immunity | 2016 |
| 74 | TFtoChromatin | Transcription factor binding as a function of chromatin | 2017 |
| 75 | epiGERMetics | Landscape of epigenetic control in early and late germ line development | 2016 |
| 76 | ProNeurons | Transcription Factor-mediated Neuronal Cell Fate Programming in Human Stem Cells | 2016 |
| 77 | EVI1inCancer | Overcoming the epigenetic and therapeutic barrier of EVI1-overexpressing cancers | 2016 |
| 78 | TranslationRegCode | Cracking the Translation Regulatory Code | 2016 |
| 79 | GeneBodyMethylation | Resolving the Nuts and Bolts of Gene Body Methylation | 2016 |
| 80 | PolyDomFormFuncReg | Discovering how polycomb domains form and function in gene regulation | 2016 |
| 81 | Spotifly | Genetic paths underlying the convergent evolution of pigmented spots on fly wings | 2016 |
| 82 | UNRAVEL | Understanding the Role of Antisense lncRNA in Vernalization, Memory and Life History | 2016 |
| 83 | G4-PTROs | Regulatory network of G-quadruplex dependent Post-Transcriptional mRNA Operons (PTROs) | 2016 |
| 84 | plaNET-seq | Temporal mapping of environmental sensing transcription dynamics in Arabidopsis thaliana | 2017 |
| 85 | MONOCLE | A novel enhancer deletion strategy to determine non-classical monocyte function in atherosclerosis | 2017 |
| 86 | DISTRICT | DECIPHERING THE ROLE OF TRIB1 IN REGULATORY T CELLS | 2017 |
| 87 | GRNHairCell | Understanding the Gene Regulatory Network involved inner ear Hair Cell differentiation | 2016 |
| 88 | POL2-TFIID | The impact of TFIID on the transcription initiation machinery – a structural perspective. | 2016 |
| 89 | MIR-CHROM-C | Investigating the microRNA-chromatin remodelling circuitry in cardiac development | 2016 |
| 90 | PyroPhosphoProtein | Site-selective chemical pyrophosphorylation of proteins using tag-and-modify approach. | 2016 |
| 91 | REFOLDAMER | Communication through Polarity-Switchable Foldamers | 2016 |
| 92 | TF3C_EM | Structure-function studies of the general transcription factor IIIC (TFIIIC) | 2017 |
| 93 | TransposonsReprogram | How retrotransposons remodel the genome during early development and reprogramming | 2016 |
| 94 | ZPR | The Pancreas Regulome: From causality to prediction of non-coding mutations in human pancreatic diseases | 2016 |
| 95 | IdrSeq | Discovery and characterization of functional disordered regions and the genes involved in their regulation through next generation sequencing | 2016 |
| 96 | GCB-PRID | Post-transcriptional Regulation of Germinal Center B Cell Responses in Immunity and Disease | 2016 |
| 97 | DELMIT | Maintaining the Human Mitochondrial Genome | 2016 |
| 98 | AGE-MEMORY | Identification of insulin signalling factors that delay age-related memory impairment | 2016 |
| 99 | Tissue-Tregs | Novel approaches to determining the function of tissue-specific regulatory T cells | 2016 |
| 100 | NEURAM | Visual genetics: establishment of a new discipline to visualize neuronal nuclear functions in real-time in intact nervous system by 4D Raman spectroscopy | 2016 |
| 101 | CHROMTOPOLOGY | Understanding and manipulating the dynamics of chromosome topologies in transcriptional control | 2016 |
| 102 | TRANSREG | Structural and biochemical studies on the regulation of transcription during elongation | 2016 |
| 103 | PIWI-Chrom | Understanding small RNA-mediated transposon control at the level of chromatin in the animal germline | 2016 |
| 104 | Gen-Epix | Genetic Determinants of the Epigenome | 2016 |
| 105 | TRANSREGULON | Structural biology of mammalian transcription regulation | 2016 |
| 106 | Totipotency | Transcriptional and Epigenetic Regulation of Totipotency in Mouse Early Embryos. | 2016 |
| 107 | RAMBO | Mitochondrial DNA degradation and sterile inflammation in the heart | 2016 |
| 108 | MEDICI | The inflammatory gene expression program in macrophages: An integrative approach for the systematic characterization of transcriptional co-regulators | 2016 |
| 109 | TRANSDAM | The transcription-related DNA damage response | 2016 |
| 110 | MMDYNASYS | Molecular Motors, powering dynamic functional molecular systems | 2016 |
| 111 | CDK6-DrugOpp | CDK6 in transcription - turning a foe in a friend | 2016 |
| 112 | LSDiASD | Leveraging Small Demethylase inhibitors for Autism Spectrum Disorder | 2016 |
| 113 | EPIScOPE | Reversing the epigenetic state of oligodendrocyte precursors cells in multiple sclerosis | 2016 |
| 114 | TransSplicHD | Single-Cell Transcriptomics and Spliceosome analysis to uncover new mechanisms of neuronal vulnerability to Huntington’s Disease. | 2016 |
| 115 | Neobetacell | Neogenesis of new functional Beta Cells through Modulation of Neurogenin-3 Expression to provide Regenerative Therapy for Diabetes Patients | 2016 |
| 116 | HOXA9 degradome | Deciphering the machinery involved in stability of the transcription factor HOXA9. | 2016 |
| 117 | transcriPTIon | Understanding transcriptional regulation in plant PAMP-triggered immunity | 2016 |
| 118 | REMIX | Regulation of mitochondrial expression | 2016 |
| 119 | MacAGE | Macrophage aging and rejuvenation | 2017 |
| 120 | SYNC_DEV | The importance of transcriptional coordination during development | 2017 |
| 121 | BIOCDx | A miniature Bio-photonics Companion Diagnostics platform for reliable cancer diagnosis and treatment monitoring. | 2017 |
| 122 | DiVineGenoMe | Decoding cell-to-cell variation in genome integrity maintenance | 2017 |
| 123 | HiChemSynPro | High-throughput combinatorial chemical protein synthesis as a novel research technology platform for chemical and synthetic biology | 2017 |
| 124 | ACEnano | Analytical and Characterisation Excellence in nanomaterial risk assessment: A tiered approach | 2017 |
| 125 | VISGEN | Transcribing the processes of life: Visual Genetics | 2017 |
| 126 | NGECA | REGULATION OF NEURONAL GENE EXPRESSION THROUGH CHROMOSOME ARCHITECTURE | 2016 |
| 127 | GasPlaNt | Gas sensing in plants:Oxygen- and nitric oxide-regulated chromatin modification via a targeted protein degradation mechanism | 2017 |
| 128 | Mushroomics | Functional genomics in Schizophyllum commune: leveraging the diversity in this hypervariable fungus to understand mushroom development | 2017 |
| 129 | GENE FOR CURE | Expanding and extending gene therapy of monogenic diseases of the haematopoietic system | 2016 |
| 130 | MiniBrain | Cerebral Organoids: Using stem cell derived 3D cultures to understand human brain development and neurological disorders | 2017 |
| 131 | RetroNets | Reverse Engineering Gene Regulatory Networks | 2017 |
| 132 | BINAMA | Biomimicking nanostructured materials via intra(inter)molecular folding of sequence-controlled polymers | 2017 |
| 133 | Curtana | Patented small molecule therapeutics that target cancer stem cells for the treatment of glioblastoma and other brain cancers | 2017 |
| 134 | Targeting TopoII | Mechanistic studies of metal-dependent DNA cleavage in Type II topoisomerase toward therational design of novel anticancer drugs | 2017 |
| 135 | 3DQuant | Understanding long-range transcriptional regulation in the context of the 3D genome organization | 2017 |
| 136 | eWAD | Unbalanced Wnt signalling in AD: a DNA methylation effect | 2017 |
| 137 | Survive | Surviving metabolism: acid handling and signalling | 2017 |
| 138 | POLYAMACHINES | The polyA machinery: Elucidating the molecular mechanisms of mRNA polyadenylation, deadenylation and RNA recognition | 2017 |
| 139 | ReXeG | Deciphering molecular mechanisms that resolve mutagenic DNA G-quadruplex structures | 2017 |
| 140 | CRISTONE | Targeting CRISPR-based HDAC inhibitors to histones: a new tool for assessing mechanisms of class I HDAC inhibitors and developing chemical probes. | 2017 |
| 141 | Repro_organoid | Direct reprogramming of human astrocytes into functional neurons in cerebral organoids derived from genome edited hiPSCs | 2017 |
| 142 | MetEpiStem | Dissecting the crosstalk between metabolism and transcriptional regulation in pluripotent stem cells. | 2017 |
| 143 | HISTONEMEMORY | New and Old Histones in Epigenetic Cell Memory | 2017 |
| 144 | PREMETAZOAEPIGENOME | The role of genome regulation in the origin of animals | 2017 |
| 145 | QAPs | G-Quadruplex-associated proteins (QAPs) and their role in transcriptional regulation | 2017 |
| 146 | MitoDyaD | The role of the glucocorticoid receptor in dopaminoceptive neurons in mitochondrial dysfunction and vulnerability to depression | 2017 |
| 147 | DNAmethAML | Investigation of aberrant DNA methylation in malignant haematopoiesis | 2018 |
| 148 | SENSHOR | A Wearable Sensor for Hormones Based on a Native Microbial Sensing | 2017 |
| 149 | BIOSTASIS | BIOlogical SignaTures of AnhydrobioSIS via comparative transcriptomics on different evolutionary lineages within tardigrades | 2018 |
| 150 | TF-bind Determinants | Genomic binding of transcription factors as a function of DNA affinity and chromatin. | 2017 |
| 151 | DesProtDNA | Computational design of proteins binding nucleosomal DNA with specificity for therapeutic applications | 2017 |
| 152 | EwiSarc | A novel in vivo platform to study and target undruggable Ewing onco-chimera. | 2017 |
| 153 | StressEBOV | Ebola virus manipulation of the cellular stress responses | 2017 |
| 154 | IN-PLANTO_CUES | INTEGRATION OF PLANT ORGANELLE COMMUNICATION UNDER ENVIRONMENTAL STRESS | 2018 |
| 155 | Brain_stability | Elucidating novel post-transcriptional regulatory mechanisms in neural development | 2017 |
| 156 | EpiScope | Epigenomics and chromosome architecture one cell at a time | 2017 |
| 157 | DUALITY | An Integrated Computational and Experimental Approach to Rapid Synthesis of Highly Selective Dual-Targeted HDAC/CK2, MMP2/CK2 Inhibitors | 2018 |
| 158 | miRStem | Reprogramming of elite B cells to induced hematopoietic stem cell with microRNAs and transcription factors | 2017 |
| 159 | PFIMDULA | Post-translational modifications during floral initiation: molecular dissection of the UFO-dependent LFY activation | 2017 |
| 160 | HERPES | Herpesvirus Effectors of RNA synthesis, Processing, Export and Stability | 2017 |
| 161 | HemTree2.0 | Single cell genomic analysis and perturbations of hematopoietic progenitors: Towards a refined model of hematopoiesis | 2017 |
| 162 | BEAT | The functional interaction of EGFR and beta-catenin signalling in colorectal cancer: Genetics, mechanisms, and therapeutic potential. | 2017 |
| 163 | CHROMADAPT | The role of chromatin in the long-term adaptation of plants to abiotic stress | 2017 |
| 164 | dCas9 | Dissection of the mammalian transcription termination mechanism by CRISPRi technology. | 2017 |
| 165 | EPICODE | Programmable Readers, Writers, and Erasers of the Epigenetic Cytosine Code | 2017 |
| 166 | METACHROM | Establishment and maintenance of gene expression by heterochromatin factors | 2017 |
| 167 | StressPFCog | Mechanisms of stress-induced cognitive deficits : Role of the glucocorticoid receptor and its partners in the regulation of PFC function. | 2018 |
| 168 | KupfferCellNiche | Determining the instructive tissue signals and the master transcription factors driving Kupffer cell differentiation | 2017 |
| 169 | ALLERGUT | Mucosal Tolerance and Allergic Predisposition: Does it all start in the gut? | 2017 |
| 170 | Redox Relays | Detecting, understanding and exploiting intracellular redox signaling relays | 2017 |
| 171 | Epiherigans | Writing, reading and managing stress with H3K9me | 2017 |
| 172 | NeuroRibo | Specialized Ribosomes for Neuronal Protein Synthesis | 2017 |
| 173 | PlasmaCellControl | Transcriptional control of plasma cell development and function | 2018 |
| 174 | Dam2Age | DNA Damage and Repair and its Impact on Healthy Ageing | 2017 |
| 175 | BURSTREG | Single-molecule visualization of transcription dynamics to understand regulatory mechanisms of transcriptional bursting and its effects on cellular fitness | 2018 |
| 176 | CHROMATADS | Chromatin Packing and Architectural Proteins in Plants | 2018 |
| 177 | BioMeTRe | Biophysical mechanisms of long-range transcriptional regulation | 2018 |
| 178 | SC-EpiCode | Decoding the Epigenomic Regulatory Code by the Use of Single Cell Technologies | 2017 |
| 179 | StroMaP | Stromal stress networks underlying phenotypic plasticity and tumor fitness | 2017 |
| 180 | PUNCTUATION | Pervasive Upstream Non-Coding Transcription Underpinning Adaptation | 2018 |
| 181 | 4D-GenEx | Spatio-temporal Organization and Expression of the Genome | 2018 |
| 182 | TarMyc | Targeting the Oncogenic Function of Myc in vivo | 2018 |
| 183 | CellKarma | Dissecting the regulatory logic of cell fate reprogramming through integrative and single cell genomics | 2018 |
| 184 | SPOCkS MS | Sampling Protein cOmplex Conformational Space with native top down Mass Spectrometry | 2018 |
| 185 | Trans C4 | Deciphering Regulatory DNA and Transcription Factor Binding Sites in C3 and C4 Species with Varying Water Use Efficiencies | 2018 |
| 186 | BioMatrix | Structural Biology of Exopolysaccharide Secretion in Bacterial Biofilms | 2018 |
| 187 | miRCell | MicroRNA functions in single cells | 2018 |
| 188 | DrySeasonPf | Dry season P. falciparum reservoir | 2018 |
| 189 | Enhancer3D | Regulatory genomics during Drosophila embryogenesis: dissecting enhancer-promoter interactions | 2018 |
| 190 | StemCellHabitat | Metabolic and Timed Control of Stem Cell Fate in the Developing Animal | 2018 |
| 191 | RECEIVE | Regulatory networks of plant cell rearrangement during symbiont accommodation | 2018 |
| 192 | SysOrganoid | A systems biology approach to investigate cell fate switches in intestinal organoids | 2018 |
| 193 | REBUILDCNS | Redirecting glial progenitor fate to rebuild the injured Brain | 2018 |
| 194 | Verbatizer | A cutting edge transcription process and technology revolutionizing the transcription industry. | 2018 |
| 195 | MetaRegulation | Metabolic regulation of metastatic growth | 2018 |
| 196 | TCAPS | mRNA cap regulation and function in CD8 T cells | 2018 |
| 197 | WISDOM | The autonomous floral pathway: a WIndow to Study the tight link between non-coDing RNA and chrOMatin regulation | 2018 |
| 198 | EpiSyStem | Epigenetics and System Biology of Stem cells and Reprogramming | 2018 |
| 199 | BinD | Mitotic Bookmarking, Stem Cells and early Development | 2018 |
| 200 | FUNBIOSIS | Mediators in plant pathogenic fungal-bacterial symbiosis | 2018 |
| 201 | TiPS-DNA | Transcription-induced Plectonemic Supercoiled DNA | 2018 |
| 202 | PLANT-RNA-MET | A newly discovered role for mRNA methylation in controlling plant gene expression | 2018 |
| 203 | ChemRAS | Chemical probing of transcriptional RAS effectors | 2019 |
| 204 | CRISPR-GQ | Identifying the Capabilities and Limitations of CRISPR in Targeting G-quadruplex Forming Sequences: From Target Recognition to Gene Expression Regulation | 2018 |
| 205 | CRoSh | “Chromatin Re-organization during Shade Avoidance” | 2019 |
| 206 | DynaTweezers | DynaTweezers: Elucidating the Molecular Mechanisms of Bacterial Gene Silencing using Tethered Particles and Optical Tweezing | 2018 |
| 207 | EmBd | Unravelling the molecular mechanisms of monocot embryogenesis | 2019 |
| 208 | NucleolusChromatin | Analysis of the nucleolus in genome organization and function | 2018 |
| 209 | MetChromTx | Macrophage metabolism and signal-induced chromatin and transcription changes: an integrated, multi-layer approach | 2018 |
| 210 | HifLICs | Acute Myeloid Leukemia Leukemic Initiating Cells: Contribution of hypoxia/HIF pathway to chemoresistance and relapse | 2019 |
| 211 | TFs-HSCs | The identification of the Combinatorial Transcription Factor network exerting different roles in Hematopoietic Stem Cells. | 2019 |
| 212 | FLYMEN | A Drosophila model for understanding the basis of Meniere’s disease | 2019 |
| 213 | rDNAstress | Novel insights into DNA damage and stress responses in the nucleolus: Mechanisms and relevance for genomic (in)stability and cancer | 2019 |
| 214 | AvINFLUENZA | Molecular basis of avian influenza polymerase adaptation to human hosts | 2019 |
| 215 | RNAfate | Identifying RNA fate checkpoints by resolving the high-resolution spatiotemporal binding dynamics of CBC containing complexes | 2019 |
| 216 | EpiShade | Deciphering the epigenetic components of the Shade Avoidance Syndrome in Arabidopsis | 2019 |
| 217 | IMPACT-HEALTH | IMaging Pancreatic Alpha-cells Calcium Tied with HEterogeneous Analysis of Labeled Transcription factors with in situ Hybridization | 2018 |
| 218 | ZELDA | Investigating the mechanism of spatiotemporal control over genome activation by Zelda in an in vitro reconstituted system | 2019 |
| 219 | EpiNoise | The role of epigenetic heterogeneity in cell fate decisions | 2019 |
| 220 | SC-EpiTranscriptome | Investigating differentiation using parallel single cell transcriptomic and epigenomic analysis | 2019 |
| 221 | EpiTFeb | Deciphering the Transcriptional Logic of TFEB activation in cell identity and cancer | 2018 |
| 222 | NINTCORDEV | NIPBL and Integrator function and dysfunction in human cortical development | 2018 |
| 223 | NeuroRBP | Studying RNA-binding proteins involved in neural differentiation and degeneration | 2019 |
| 224 | HybReader | Mechanisms of epigenetic gene regulation by R-loops | 2018 |
| 225 | NeuralCellTypeEvo | Cellular innovation driving nervous system evolution | 2018 |
| 226 | SOLO | Single cell omics of the Oligodendrocyte Lineage in develOpment and disease | 2018 |
| 227 | CTCFStableGenome | CTCF control of genome stability in ageing | 2019 |
| 228 | REPLISTRESS | DNA Replication: From Physiology to Replication Stress in Human Cancer | 2018 |
| 229 | BONE-JOINT-MORPH | Mechanobiology of Proprioceptive Regulation of Bone and Joint Morphogenesis | 2018 |
| 230 | HemoScreen | Point-of-care hematology analyser based on visco-elastic focusing, digital imaging, image processing and machine learning | 2018 |
| 231 | SkinTrmDeep | Tissue Resident Memory (Trm) CD8+ T cells: Genome-wide dissection of cellular differentiation and heterogeneity | 2019 |
| 232 | Myel-IN-Crisis | Myelin at the crossroads of Development and Disease | 2018 |
| 233 | aDDRess | Joint Training and Research Program on Chromatin Dynamics and the DNA Damage Response | 2019 |
| 234 | DiRECT | Directly reprogrammed renal cells for targeted medicine | 2019 |
| 235 | IM-ID | Defining the intrinsic transcriptional programs and the microenvironmental signals tailoring lung Interstitial Macrophage IDentity | 2019 |
| 236 | DNAProteinCrosslinks | DNA-protein crosslinks: endogenous origins and cellular responses. | 2019 |
| 237 | Neuro-UTR | Mechanism and functional impact of ultra-long 3’ UTRs in the Drosophila nervous system | 2019 |
| 238 | SM-Epigen | Revealing the Epigenetic Regulatory Network with Single-Molecule Precision | 2018 |
| 239 | PHARMS | Bacteriophage inhibition of antibiotic-resistant pathogenic microbes and founding for novel therapeutic strategies | 2019 |
| 240 | Combat_ALS | Development of new chemical tools to combat ALS | 2019 |
| 241 | EAGER | Elucidating the effects of ageing on the nucleoporin-directed neural cell type-specific nuclear architecture and gene regulation | 2019 |
| 242 | BARINAFLD | Using Bariatric Surgery to Discover Weight-Loss Independent Mechanisms Leading to the Reversal of Fatty Liver Disease | 2018 |
| 243 | SafeFate | Safeguarding Cell Fate by Terminal Repression during Development and Disease | 2019 |
| 244 | HDPROBES | Photoactivatable Sensors and Blinking Dyes for Live-Cell, Single-Molecule Localization Microscopy | 2019 |
| 245 | TotipotentZygotChrom | Mechanisms of chromatin organization and reprogramming in totipotent mammalian zygotes | 2020 |
| 246 | SCHIZTYPE | Brain cell type-specific interactions and schizophrenia | 2019 |
| 247 | DNACom | Compartmentalized DNA Computers for In-Vitro Diagnostic Applications | 2019 |
| 248 | Diverge | Generation of ultra-deep libraries of transcriptional activators for gene therapy | 2019 |
| 249 | ChaperoneRegulome | ChaperoneRegulome: Understanding cell-type-specificity of chaperone regulation | 2020 |
| 250 | TRANSLIGHT | Light-dependent composition of transcriptional complexes in plants | 2019 |
| 251 | IRF4 Degradation | Using a novel protein degradation approach to uncover IRF4-regulated genes in plasma cells | 2019 |
| 252 | RoBE | Study of the role of BANK1 in antibody production and antibody-independent functions of B cells in SLE | 2019 |
| 253 | TERMINATOR | Ribosomal frameshifts as a novel mechanism to control RNA turnover in stress | 2019 |
| 254 | STRATOS | SOCP-Tailored Real-time Algorithm for Trajectory Onboard Synthesis | 2020 |
| 255 | uTSSreg | Regulation of mammalian genes by new classes of promoter proximal transcription start sites | 2020 |
| 256 | EmbryoPAINT | PAINTing the architecture of the totipotency gene network during early mammalian development | 2020 |
| 257 | StopIG | Translating fundamental insights in podocyte metabolism and cell cycle regulation: development of a new treatment for Stopping crescentic Immune Glomerulonephritis | 2019 |
| 258 | UMMATR | Uncovering molecular mechanisms of active transcriptional repression. | 2020 |
| 259 | InvADeRS | Investigating the Activity of transposon Derived Regulatory Sequences in the placenta | 2019 |
| 260 | IDEAL | Inhibitor of DUX4-IGH to Erase Acute lymphoblastic Leukaemia | 2020 |
| 261 | miRhythm | Understanding mechanisms and functions of miRNA oscillations during development | 2020 |
| 262 | SingleCellAI | Deep-learning models of CRISPR-engineered cells define a rulebook of cellular transdifferentiation | 2019 |
| 263 | ChromaSTORM | Visualising how proteins fold DNA into topologically associating domains in single human cells | 2020 |
| 264 | RegRNA | Mechanistic principles of regulation by small RNAs | 2019 |
| 265 | RegulatioNFkB | Deciphering transcriptional regulation of NF-kB target genes using integrative omics approaches | 2019 |
| 266 | MultiPan | A Multi-omics Approach To Decode Epigenetic Lesions In Pancreatic Cancer Development | 2019 |
| 267 | MIMIC | Deciphering how microbiota modulate anti-tumor immune responses in checkpoint therapy | 2020 |
| 268 | GainGrain | Understanding genetic hubs in rice inflorescence architecture to increase grain yield | 2019 |
| 269 | CB-103 | First effective targeted therapy for T-cell acute lymphoblastic leukemia (T-ALL) and other NOTCH pathway driven cancers | 2019 |
| 270 | GHSO | Generation of human steroid-producing organoids: a new approach to treat adrenal insufficiency | 2019 |
| 271 | JS_SCZ | Investigating impact of schizophrenia-associated non-coding variants on enhancer activity using brain organoids | 2020 |
| 272 | inSight | Moving a novel gene therapy paradigm to treat blindness to the market | 2019 |
| 273 | Breakborder | Breaking borders, Functional genetic screens of structural regulatory DNA elements | 2019 |
| 274 | NGI | Next Generation Imaging | 2019 |
| 275 | CLOCK | Characterization of the circadian chromatin landscape using a novel CRISPR/Cas9-guided proximity-labelling technique | 2020 |
| 276 | RepDiff | Revealing novel molecular mechanisms linking DNA replication and cell fate decisions | 2020 |
| 277 | FunStructure | Interdependence of functional and structural plasticity in cerebellar climbing fibers in health and disease | 2019 |
| 278 | RetroChrom | Deciphering the molecular mechanisms of HIV DNA nuclear import and the impact of 3D genome organization on integration site selection | 2019 |
| 279 | DynamicAssemblies | Conformational studies of highly dynamic viral replication complexes | 2019 |
| 280 | RiboMed | RNA in disease | 2019 |
| 281 | TaMIE | Targeting MarA to Inhibit Efflux | 2019 |
| 282 | MetaboSENS | Metabolic integration by nutrient SENSing | 2019 |
| 283 | CN Identity | Comprehensive anatomical, genetic and functional identification of cerebellar nuclei neurons and their roles in sensorimotor tasks | 2019 |
| 284 | SUMiDENTITY | Deconstructing the role of SUMO on chromatin in cell identity and tissue repair | 2020 |
| 285 | ConflictResolution | Transcription-replication conflicts in disease and development | 2020 |
| 286 | OCTOBER | Control of cell identity in pluripotent and germline cells by OCT4 orchestration of chromatin binding and enhancer regulation | 2019 |
| 287 | DecodeDegRNA | Post-transcriptional regulation of RNA degradation in early zebrafish development | 2020 |
| 288 | TrojanDC | TrojanDC | 2019 |
| 289 | CHROMREP | Dissecting the chromatin response to DNA damage in silenced heterochromatin regions | 2019 |
| 290 | PLASTINET | Plasticity of the Pluripotency Network | 2020 |
| 291 | RARITY | RAtional design of canceR ImmunoTherapY: one size does not fit all | 2019 |
| 292 | HDM-FUN | Host directed medicine in invasive fungal infection | 2020 |
| 293 | NUCDDR | Nucleolar Responses to DNA Damage: rDNA, an emerging hub of genome instability | 2020 |
| 294 | DYNOME | Barcoding gene expression dynamics at single-molecule resolution | 2020 |
| 295 | RiboTrace | Bridging temporal resolution gaps to dissect RNA silencing at the molecular and genomic scale | 2020 |
| 296 | SILENT | Silent mutations in cancer | 2020 |
| 297 | TrojanDC | Harnessing dendritic cell reprogramming for cancer immunotherapy | 2020 |
| 298 | PCOMOD | Targeting the Plant Cysteine Oxidases to Regulate Plant Stress Tolerance | 2020 |
| 299 | H I C I | Transcriptional and epigenetic control of tissue regenerative HB-EGF in autoimmune CNS inflammation | 2020 |
| 300 | NEMABOX | Deciphering the cyst nematode parasitic program by uncovering how their virulence is orchestrated | 2020 |
| 301 | TAXi-ch | Determination of transcription factor cooperativity driving expression from the inactive X chromosome | 2020 |
| 302 | FatTFIso | Characterizing the roles of transcription factor isoforms in rewiring gene regulatory networks during adipogenesis | 2020 |
| 303 | UCUPA | Unraveling the Molecular Changes that Drive the Repression of the Unfolded Protein Response with Ageing | 2020 |
| 304 | Turbo-MPMI-Discovery | TurboID-charging discovery of plant pathogen virulence and host resistance mechanisms | 2020 |
| 305 | dcPolyWheat | Dominant cis-regulatory variation to improve quantitative traits in polyploid wheat | 2020 |
| 306 | DREAM | Dux4-Regulated Expression and Activity by MATR3 | 2020 |
| 307 | Pituitary enhancers | Identification and functional validation of novel enhancer sequences involved in pituitary gland development and pathology | 2020 |
| 308 | MacrophageEGR | Egr1 and Egr2 regulate opposite transcriptional programs in macrophages | 2021 |
| 309 | ChRONAM-H | Chromatin Regulation Of Normal And Malignant Haematopoiesis | 2020 |
| 310 | GLoopID | Mechanisms underlying regulation and removal of G-quadruplex/R-loop transcription-replication conflicts | 2021 |
| 311 | POL2-TERM | Structural basis of co-transcriptional pre-mRNA 3’-end processing | 2020 |
| 312 | ERA | Epigenetic Regulation in Acinetobacter baumannii | 2020 |
| 313 | PDASwITch | Super-enhancer modules controlling plasticity and response to therapy in pancreatic cancer | 2020 |
| 314 | PLIM-G4 | Long-lived optical probes to image G-quadruplex DNA in live cells | 2021 |
| 315 | Xerobranching | Xero-Branching: discovering how plant roots adapt to reduced water availability | 2021 |
| 316 | MRTFSen | MRTF/SRF signalling in regulation of cell senescence and melanoma progression | 2020 |
| 317 | Catenin-Condensation | The effect of β-catenin condensation on the Wnt-pathway | 2020 |