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RADAR-CNS SIGNED

Remote Assessment of Disease and Relapse in Central Nervous System Disorders - Sofia ref.: 115902

Total Cost €

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EC-Contrib. €

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Partnership

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 RADAR-CNS project word cloud

Explore the words cloud of the RADAR-CNS project. It provides you a very rough idea of what is the project "RADAR-CNS" about.

payers    data    barriers    adverse    infrequent    imi2    collect    monitor    services    public    patients    burden    active    inefficient    strategy    sensors    passively    time    innovation    sclerosis    events    collected    regulator    remote    multiple    providers    smartphone    oversight    predictive    gleaned    components    whilst    excellent    ideal    unnecessary    clinicians    depression    rmt    overcome    technologies    exponential    epilepsy    pipeline    clinic    care    amount    flexibility    patient    risk    inherent    applicable    infancy    approval    private    feasibility    place    partnership    relapse    led    responsive    power    fostered    facilitators    provides    cumbersome    grained    sampling    background    outcomes    optimise    disease    ultimate    infrastructure    visits    monitoring    health    unobtrusively    proofed    too    wearable    treatment    fine    create    regulatory    disorders    technological    efficient    individuals    course    implementing   

Project "RADAR-CNS" data sheet

The following table provides information about the project.

Coordinator
KING'S COLLEGE LONDON 

Organization address
address: STRAND
city: LONDON
postcode: WC2R 2LS
website: www.kcl.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.radar-cns.org/
 Total cost 25˙712˙110 €
 EC max contribution 11˙000˙000 € (43%)
 Programme 1. H2020-EU.3.1.7. (Innovative Medicines Initiative 2 (IMI2))
 Code Call H2020-JTI-IMI2-2015-03-two-stage
 Funding Scheme IMI2-RIA
 Starting year 2016
 Duration (year-month-day) from 2016-04-01   to  2021-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KING'S COLLEGE LONDON UK (LONDON) coordinator 4˙014˙496.00
2    STICHTING LYGATURE NL (UTRECHT) participant 1˙345˙962.00
3    UNIVERSITAETSKLINIKUM FREIBURG DE (FREIBURG) participant 825˙000.00
4    CONSORCIO CENTRO DE INVESTIGACION BIOMEDICA EN RED M.P. ES (MADRID) participant 674˙981.00
5    THE UNIVERSITY OF NOTTINGHAM UK (NOTTINGHAM) participant 642˙500.00
6    STICHTING VUMC NL (AMSTERDAM) participant 585˙000.00
7    KATHOLIEKE UNIVERSITEIT LEUVEN BE (LEUVEN) participant 506˙000.00
8    UNIVERSITA VITA-SALUTE SAN RAFFAELE IT (MILANO) participant 487˙250.00
9    FUNDACIO HOSPITAL UNIVERSITARI VALL D'HEBRON - INSTITUT DE RECERCA ES (BARCELONA) participant 437˙235.00
10    UNIVERSITAET AUGSBURG DE (AUGSBURG) participant 433˙647.00
11    REGION HOVEDSTADEN DK (HILLEROD) participant 430˙000.00
12    PROVINCIA LOMBARDO VENETA - ORDINEOSPEDALIERO DI SAN GIOVANNI DI DIO- FATEBENEFRATELLI IT (BRESCIA) participant 180˙000.00
13    UNIVERSITA' DEGLI STUDI DI BERGAMO IT (BERGAMO) participant 125˙000.00
14    UNIVERSITAT PASSAU DE (PASSAU) participant 116˙352.00
15    STICHTING IMEC NEDERLAND NL (EINDHOVEN) participant 111˙000.00
16    CHARITE - UNIVERSITAETSMEDIZIN BERLIN DE (BERLIN) participant 62˙500.00
17    GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG DE (MUENCHEN) participant 23˙076.00
18    BIOGEN IDEC LIMITED UK (MAIDENHEAD) participant 0.00
19    H. LUNDBECK AS DK (VALBY) participant 0.00
20    INTEL CORPORATION (UK) LIMITED UK (SWINDON) participant 0.00
21    JANSSEN PHARMACEUTICA NV BE (BEERSE) participant 0.00
22    MSD CZECH REPUBLIC SRO CZ (PRAHA) participant 0.00
23    NORTHWESTERN UNIVERSITY US (EVANSTON, ILLINOIS) participant 0.00
24    SOFTWARE AG DE (DARMSTADT) participant 0.00
25    UCB BIOPHARMA SRL BE (BRUXELLES) participant 0.00

Map

 Project objective

Background: Long term conditions require monitoring of patients, traditionally conducted in the clinic, to monitor treatment effects, adverse events and disease course. This can be inefficient and cumbersome – clinic visits may be too infrequent to identify individuals at risk of significant changes in disease state (e.g. relapse) and place unnecessary burden on patients and providers.

Smartphone and wearable technologies have led to an exponential growth in the amount of information which can be collected on patients unobtrusively and at low cost. Sensors collect data passively, and active monitoring, using experience sampling, provides information on multiple parameters. Such technologies could monitor long term outcomes of patients, at scale, and provide fine-grained information on outcomes, available in real time and at low-cost, enabling services to offer more responsive and efficient care.

Whilst there is growing interest in the application of RMT in health, the field is in its infancy. The private-public partnership fostered by IMI2 is an ideal way to overcome the inherent challenges of this field.

Our ultimate goal is to improve patient outcomes through remote assessment. To achieve this we will create a pipeline for developing, testing and implementing RMT in depression, multiple sclerosis and epilepsy. The pipeline will include a data management and modelling infrastructure applicable to other disorders and with the flexibility of design to be future-proofed against further technological innovation. We will provide data on implementation barriers and facilitators gleaned from patients, clinicians, regulator and payers which will optimise the pathways for regulatory approval and uptake.

Program of Work: In order to test the feasibility and predictive power of RMT four main components are required: (1) Excellent project oversight, management, and a dissemination and exploitation strategy;

 Deliverables

List of deliverables.
Report on second annual meeting Documents, reports 2020-04-08 20:53:54
Coordinated summary report of technical and clinical work package response to expert elicitation Documents, reports 2020-04-08 20:53:54
Year three update report on learnings with regard to regulatory requirements Documents, reports 2020-04-08 20:53:54
Completion of literature review Documents, reports 2020-04-08 20:53:54
Report on the state of recruitment and of the protocol advances in both the ongoing studies Documents, reports 2020-04-08 20:53:54
Second Periodic Report Documents, reports 2020-04-08 20:53:54
Completion of protocol and local ethics approval for project 1 Documents, reports 2020-04-08 20:53:52
Submit ethical approvals by the competent legal local/national Ethics Boards/Bodies to IMI Documents, reports 2020-04-08 20:53:52
First Periodic Report Documents, reports 2020-04-08 20:53:52
Analysis of the results obtained by the focus group in MS patients Documents, reports 2020-04-08 20:53:52
Year one update report on learnings with regard to regulatory requirements Documents, reports 2020-04-08 20:53:53
Report on first annual meeting Documents, reports 2020-04-08 20:53:53
Provide IMI with measures taken to prevent risk of enhancing vulnerability and stigmatisation of individuals/groups Documents, reports 2020-04-08 20:53:52
Production of a detailed description of the definite RMT package which will be used in MS patients Documents, reports 2020-04-08 20:53:52
Interim report on feasibility and acceptability of RMT Documents, reports 2020-04-08 20:53:52
Protocols development and achievement of local ethic approval Documents, reports 2020-04-08 20:53:52
Define list of variables to be included in assessment scheme Other 2020-04-08 20:53:52
A report on stakeholder views of RMT in epilepsy, collating information from focus groups, expert workshops and other fora Documents, reports 2020-04-08 20:53:52
Preliminary report on pathways, decision points and stakeholder requirements relating to the three disease areas Documents, reports 2020-04-08 20:53:53
Interim report on recruitment to RADAR-MDD Documents, reports 2020-04-08 20:53:53
Primer with regulatory requirements for RMT Documents, reports 2020-04-08 20:53:53
Submission of ethics approvals to IMI Documents, reports 2020-04-08 20:53:53
Completion of RADAR-MDD study protocol and ethics approval, supplemented by learnings of Orbit data Documents, reports 2020-04-08 20:53:52
Report on Kick-Off meeting Documents, reports 2020-04-08 20:53:52
Report on mental capacity and consent issues. Template for informed consent for all disease areas in RADAR-CNS. Documents, reports 2020-04-08 20:53:52
Individualized press release for every partner Documents, reports 2020-04-08 20:53:53
Year two update report on learnings with regard to regulatory requirements Documents, reports 2020-04-08 20:53:53
Launch of website, Twitter, LinkedIn Other 2020-04-08 20:53:53

Take a look to the deliverables list in detail:  detailed list of RADAR-CNS deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Zixing Zhang, Jing Han, Kun Qian, Björn Schuller
Evolving Learning for Analysing Mood-Related Infant Vocalisation
published pages: 142-146, ISSN: , DOI: 10.21437/interspeech.2018-1914
Interspeech 2018 2020-04-08
2019 F. Matcham, C. Barattieri di San Pietro, V. Bulgari, G. de Girolamo, R. Dobson, H. Eriksson, A. A. Folarin, J. M. Haro, M. Kerz, F. Lamers, Q. Li, N. V. Manyakov, D. C. Mohr, I. Myin-Germeys, V. Narayan, Penninx BWJH, Y. Ranjan, Z. Rashid, A. Rintala, S. Siddi, S. K. Simblett, T. Wykes, M. Hotopf
Remote assessment of disease and relapse in major depressive disorder (RADAR-MDD): a multi-centre prospective cohort study protocol
published pages: , ISSN: 1471-244X, DOI: 10.1186/s12888-019-2049-z
BMC Psychiatry 19/1 2020-04-08
2018 Eva-Maria Rathner, Julia Djamali, Yannik Terhorst, Björn Schuller, Nicholas Cummins, Gudrun Salamon, Christina Hunger-Schoppe, Harald Baumeister
How Did You like 2017? Detection of Language Markers of Depression and Narcissism in Personal Narratives
published pages: 3388-3392, ISSN: , DOI: 10.21437/interspeech.2018-2040
Interspeech 2018 2020-04-08
2019 Sara Simblett, Faith Matcham, Sara Siddi, Viola Bulgari, Chiara Barattieri di San Pietro, Jorge Hortas López, José Ferrão, Ashley Polhemus, Josep Maria Haro, Giovanni de Girolamo, Peter Gamble, Hans Eriksson, Matthew Hotopf, Til Wykes
Barriers to and Facilitators of Engagement With mHealth Technology for Remote Measurement and Management of Depression: Qualitative Analysis
published pages: e11325, ISSN: 2291-5222, DOI: 10.2196/11325
JMIR mHealth and uHealth 7/1 2020-04-08
2018 Elisa Bruno, Giulia Maira, Andrea Biondi, Mark P Richardson
Ictal hypoxemia: A systematic review and meta-analysis
published pages: 7-13, ISSN: 1059-1311, DOI: 10.1016/j.seizure.2018.10.011
Seizure 63 2020-04-08
2018 Elisa Bruno, Sara Simblett, Alexandra Lang, Andrea Biondi, Clarissa Odoi, Andreas Schulze-Bonhage, Til Wykes, Mark P. Richardson
Wearable technology in epilepsy: The views of patients, caregivers, and healthcare professionals
published pages: 141-149, ISSN: 1525-5050, DOI: 10.1016/j.yebeh.2018.05.044
Epilepsy & Behavior 85 2020-04-08
2018 Lang AR, Craven MC, Morriss RM, Hollis C.
Investigating user needs and integration of Remote Measuring Technologies into Clinical Practice
published pages: , ISSN: , DOI:
Proceedings of the 20th Triennial Congress of the International Ergonomics Association. Florence, Italy; 2018. 2020-04-08
2018 Jing Han, Zixing Zhang, Maximilian Schmitt, Zhao Ren, Fabien Ringeval, Björn Schuller
Bags in Bag: Generating Context-Aware Bags for Tracking Emotions from Speech
published pages: 3082-3086, ISSN: , DOI: 10.21437/interspeech.2018-996
Interspeech 2018 2020-04-08
2018 Björn Schuller, Stefan Steidl, Anton Batliner, Peter B. Marschik, Harald Baumeister, Fengquan Dong, Simone Hantke, Florian B. Pokorny, Eva-Maria Rathner, Katrin D. Bartl-Pokorny, Christa Einspieler, Dajie Zhang, Alice Baird, Shahin Amiriparian, Kun Qian, Zhao Ren, Maximilian Schmitt, Panagiotis Tzirakis, Stefanos Zafeiriou
The INTERSPEECH 2018 Computational Paralinguistics Challenge: Atypical and Self-Assessed Affect, Crying and Heart Beats
published pages: 122-126, ISSN: , DOI: 10.21437/interspeech.2018-51
Interspeech 2018 2020-04-08
2018 Nicholas Cummins, Alice Baird, Björn W. Schuller
Speech analysis for health: Current state-of-the-art and the increasing impact of deep learning
published pages: 41-54, ISSN: 1046-2023, DOI: 10.1016/j.ymeth.2018.07.007
Methods 151 2020-04-08
2018 Eva-Maria Rathner, Yannik Terhorst, Nicholas Cummins, Björn Schuller, Harald Baumeister
State of Mind: Classification through Self-reported Affect and Word Use in Speech.
published pages: 267-271, ISSN: , DOI: 10.21437/interspeech.2018-2043
Interspeech 2018 2020-04-08
2019 Yatharth Ranjan,, Zulqarnain Rashid, Callum Stewart, Pauline Conde, Mark Begale, Sebastian Boetcher, The Hyve, Richard Dobson, Amos Folarin, The RADAR-CNS Consortium
RADAR-base: An Open Source mHealth Platform for Collecting, Monitoring and Analyzing Data using Sensors, Wearables and Mobile Devices
published pages: , ISSN: 2291-5222, DOI: 10.2196/11734
JMIR mHealth and uHealth 2020-04-08
2017 Nobilia F, Kerz M, Borgdorff J, Campos H4, Moinat M, Mahasivam N, Begale M, Dobson R, Folarin AA; The RADAR-CNS Consortium
The RADAR platform:an open source generalised mHealth data pipeline
published pages: , ISSN: , DOI:
7th International Conference on Digital Health, July 2017 https://hijournal.bcs.org/index.php/jhi/article/view/939/979 2020-04-08
2018 Sara Simblett, Ben Greer, Faith Matcham, Hannah Curtis, Ashley Polhemus, José Ferrão, Peter Gamble, Til Wykes
Barriers to and Facilitators of Engagement With Remote Measurement Technology for Managing Health: Systematic Review and Content Analysis of Findings
published pages: e10480, ISSN: 1438-8871, DOI: 10.2196/10480
Journal of Medical Internet Research 20/7 2020-04-08
2017 Simblett, S.K., Ferrao, J., Gamble, P., Wykes, T. & the RADAR-CNS consortium
Digital solutions in healthcare: user experiences in accessing and adopting supportive technologies
published pages: 1-3, ISSN: , DOI:
COFACE Policy Brief January 2020-04-08
2018 Elisa Bruno, Andrea Biondi, Mark P. Richardson
Pre-ictal heart rate changes: A systematic review and meta-analysis
published pages: 48-56, ISSN: 1059-1311, DOI: 10.1016/j.seizure.2018.01.003
Seizure 55 2020-04-08
2017 Bogdan Vlasenko, Hesam Sagha, Nicholas Cummins, Björn Schuller
Implementing Gender-Dependent Vowel-Level Analysis for Boosting Speech-Based Depression Recognition
published pages: 3266-3270, ISSN: , DOI: 10.21437/Interspeech.2017-887
Interspeech 2017 2020-04-08
2017 Julia Kurps, Maxim Moinat, Joris Borgdorff, Francesco Nobilia, Maximilian Kerz, Nivethika Mahasivam, Irina Pulyakhina, Matthias Dümpelmann, Herculano Campos, Mark Begale, Richard Dobson, Amos Folarin and \'The RADAR-CNS consortium\'
Research Infrastructure for processing wearable data to improve health
published pages: , ISSN: , DOI:
BOSC 2017 https://www.open-bio.org/wiki/BOSC_2017 2020-04-08
2018 Simblett, SK., Greer, B., Matcham, F., Curtis, H., Polhemus, A., Ferrao, J., Pinner, Z., Gamble, P., Wykes, T., & the RADAR-CNS consortium
Barriers and facilitators to engagement with remote measurement technology for managing health: a systematic review and content analysis of findings
published pages: n/a, ISSN: , DOI:
CBC Conference 2018: Annual Conference - Behaviour Change for Health: Digital & Beyond february 2020-04-08
2017 M. Freitag, S. Amiriparian, S. Pugachevskiy, N. Cummins, and B. Schuller
auDeep: Unsupervised Learning of Representations from Audio with Deep Recurrent Neural Networks
published pages: 1-5, ISSN: 1532-4435, DOI:
The Journal of Machine Learning Research (JMLR) vol 19 2020-04-08
2017 Simblett, S., Evans, J., Matcham, F., Meyer, N., Raedelli, M., Mulero, P., Siddi, S., de Girolama, G., Wykes, T., Hotopf, M., & the RADAR-CNS consortium
Cross-cultural and trans-diagnostic facilitators and barriers to remote assessment in healthcare for people with multiple sclerosis, epilepsy and depression: a qualitative analysis
published pages: n/a, ISSN: , DOI:
NR-SIG-WfNR july 2020-04-08
2017 Lang AR, Craven MC, Morriss RM, Hollis C.
Investigating User Identification in Remote Patient Monitoring Devices
published pages: 76, ISSN: 2306-5354, DOI: 10.3390/bioengineering4030076
Bioengineering 4/4 2020-04-08
2017 Hesam Sagha, Nicholas Cummins, Björn Schuller
Stacked denoising autoencoders for sentiment analysis: a review
published pages: e1212, ISSN: 1942-4787, DOI: 10.1002/widm.1212
Wiley Interdisciplinary Reviews: Data Mining and Knowledge Discovery 7/5 2020-04-08
2017 S. Amiriparian, M. Freitag, N. Cummins, and B. Schuller
Sequence to Sequence Autoencoders for Unsupervised Representation Learning from Audio
published pages: 3266–3270, ISSN: , DOI:
Proceedings of the Detection and Classification of Acoustic Scenes and Events 2017 Workshop (DCASE2017) november 2020-04-08
2016 Hesam Sagha, Pavel Matějka, Maryna Gavryukova, Filip Povolny, Erik Marchi, Björn Schuller
Enhancing Multilingual Recognition of Emotion in Speech by Language Identification
published pages: 2949-2953, ISSN: , DOI: 10.21437/Interspeech.2016-333
Interspeech 2016 2020-04-08
2017 Nicholas Cummins, Bogdan Vlasenko, Hesam Sagha, Björn Schuller
Enhancing speech-based depression detection through gender dependent vowel-level formant features
published pages: , ISSN: , DOI:
2020-04-08
2017 Simone Hantke, Hesam Sagha, Nicholas Cummins, Björn Schuller
Emotional Speech of Mentally and Physically Disabled Individuals: Introducing the EmotAsS Database and First Findings
published pages: 3137-3141, ISSN: , DOI: 10.21437/Interspeech.2017-409
Interspeech 2017 2020-04-08

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