Explore the words cloud of the Hepatocarcinoma IVM project. It provides you a very rough idea of what is the project "Hepatocarcinoma IVM" about.
The following table provides information about the project.
OSPEDALE SAN RAFFAELE SRL
|Coordinator Country||Italy [IT]|
|Total cost||168˙277 €|
|EC max contribution||168˙277 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2017-07-01 to 2019-06-30|
Take a look of project's partnership.
|1||OSPEDALE SAN RAFFAELE SRL||IT (MILANO)||coordinator||168˙277.00|
CD8 T cells have a key role in eliminating tumors that affect the liver. The protective capacity of these cells relies on their ability to migrate to the liver, recognize antigens and deploy effector functions. While some of the rules that characterize CD8 T cell behavior in the cancerous liver have been characterized at the population level, we have only limited knowledge of the precise dynamics of intrahepatic CD8 T cell conduct at the single-cell level. In preliminary data for this project we have developed advanced imaging techniques that allow us to dissect the interactive behavior of CD8 T cells within the mouse liver at an unprecedented level of spatial and temporal resolution. We predict that this approach, combined with a new model of hepatocellular carcinoma created ad hoc, will generate novel mechanistic insights into the spatiotemporal determinants that govern the capacity of CD8 T cells to home and function in the tumor-bearing liver.
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The information about "HEPATOCARCINOMA IVM" are provided by the European Opendata Portal: CORDIS opendata.
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