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MetaboMARKER

A metabolism-based prognostic biomarker for prostate cancer

Total Cost €

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EC-Contrib. €

0

Partnership

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 MetaboMARKER project word cloud

Explore the words cloud of the MetaboMARKER project. It provides you a very rough idea of what is the project "MetaboMARKER" about.

patients    biomarker    lack    risk    plan    exhibit    employ    lives    progress    least    intensive    frequently    enrolled    co    protected    predominantly    funds    poc    localized    pressure    final    therapy    sixth    morbidities    endangering    recurrence    societies    prostate    profound    prone    informs    recurrent    pc    strategies    tools    exhibited    harbouring    chemotherapy    framework    potentially    secondary    affordable    line    clinicians    decade    fraction    costly    mortality    impose    progressively    resist    chemical    localised    capacity    stg    health    metastasize    metabomarker    life    last    prognostic    disease    urgently    public    cancermetab    treating    commercialization    differentiate    strategy    efficient    therapies    cancer    subsequent    diagnosis    fail    escapers    treatment    therapeutic    uncertain    guidelines    prevalent    obesity    castration    treatments    men    western    prostatectomy    patent    resides    radiotherapy    15    first    responders    followed    erc    vs    age    sources    tumour    336343   

Project "MetaboMARKER" data sheet

The following table provides information about the project.

Coordinator
ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS 

Organization address
address: PARQUE TECNOLOGICO EDIFICIO 801 A
city: DERIO VIZCAYA
postcode: 48160
website: www.cicbiogune.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 150˙000 €
 EC max contribution 150˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-PoC
 Funding Scheme ERC-POC
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS ES (DERIO VIZCAYA) coordinator 150˙000.00

Map

 Project objective

Prostate cancer (PC) is the most prevalent tumour type among men. The fraction of patients that exhibit disease recurrence can reach 15% and they face an uncertain future, since this type of tumour is prone to resist to subsequent therapeutic strategies. Current guidelines for treatment of PC include prostatectomy or radiotherapy as first line therapy for localized disease, and chemical castration followed by chemotherapy for recurrent PC. The lack of capacity to identify therapy responders vs. escapers in PC is one of the sources for its important mortality. The challenge resides in providing clinicians with a robust and affordable biomarker that informs about the success of first line therapy in localised PC, and that allows them to employ more intensive therapeutic strategies in high-risk patients. The development of such prognostic tools is urgently needed, since western societies are facing profound changes in the major PC risk factors, including age and obesity. Last, but not least, the cost of treating PC will progressively impose strong pressure in the public health system. In addition, patients that fail first-line therapy can be enrolled in subsequent therapies for up to a decade, and given their advance age (PC predominantly presents in the sixth decade of life) they frequently present endangering and costly co-morbidities and secondary effects. MetaboMARKER, a novel biomarker developed in the framework of the ERC-StG-336343-CancerMetab and already protected under a European patent, is able to differentiate patients harbouring a PC that would progress and potentially metastasize, from those that exhibited a disease that would not likely be a risk to their lives. Thus, MetaboMARKER may contribute to more efficient diagnosis, improved treatments and better distribution of funds in disease management. The aim of the present PoC is to further develop the final biomarker for its commercialization and define the best exploitation strategy plan.

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The information about "METABOMARKER" are provided by the European Opendata Portal: CORDIS opendata.

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