Opendata, web and dolomites

MATURATION SIGNED

Age at maturity in Atlantic salmon: molecular and ecological dissection of an adaptive trait

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MATURATION project word cloud

Explore the words cloud of the MATURATION project. It provides you a very rough idea of what is the project "MATURATION" about.

paper    40    provides    reported    nexus    maturity    unclear    reproduction    exhibits    architecture    ultimately    locally    tightly    underlying    biology    phenotype    freshwater    atlantic    statistical    species    mechanisms    hence    sex    male    size    later    elucidate    spawn    first    maturing    genotype    gene    mechanistic    trait    candidate    sea    linked    always    off    tool    vs    link    drivers    variation    fitness    phenotypes    history    spend    trade    validate    quantitative    prior    evolutionary    biological    allelic    revolve    align    classic    salmon    questions    cover    individuals    occurs    genetics    effect    sexual    gxe    resolves    model    dying    interactions    conflict    dominance    explaining    resolution    nature    unless    remarkably    locus    larger    age    traits    survival    ecological    investigations    risk    relatively    ideal    reproductive    female    dependent    time    shaped    histories    opportunity    complicating    genetic    life    functions    combined    maturation    causes    returning    molecular    evolution    understand    quantifying   

Project "MATURATION" data sheet

The following table provides information about the project.

Coordinator
HELSINGIN YLIOPISTO 

Organization address
address: YLIOPISTONKATU 3
city: HELSINGIN YLIOPISTO
postcode: 14
website: www.helsinki.fi

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 2˙500˙000 €
 EC max contribution 2˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-ADG
 Funding Scheme ERC-ADG
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2022-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HELSINGIN YLIOPISTO FI (HELSINGIN YLIOPISTO) coordinator 2˙500˙000.00

Map

 Project objective

Life history is the nexus of biology, because various biological questions ultimately revolve around the causes and consequences of variation in reproduction and survival, i.e. fitness. Traditionally, a major tool in life-history research has been quantitative genetics because it provides an important statistical link between phenotype and genotype. However, the mechanisms by which evolution occurs may remain unclear unless such traditional approaches are combined with molecular investigations. Another complicating factor is that the fitness of male vs female life histories do not always align, and hence life history traits may be shaped by sexual conflict. This is why life-history approaches focusing on both quantifying the conflict and understanding its resolution at the genetic level are needed. As in many species, age at maturity in Atlantic salmon is tightly linked with size at maturity and thus represents a classic evolutionary trade-off: later maturing individuals spend more time at sea before returning to freshwater to spawn and have higher reproductive success due to their larger size but also have a higher risk of dying prior to first reproduction. Our recent cover paper in Nature reported a large-effect gene explaining 40% of the variation in this key life history trait. Remarkably, the locus exhibits sex-dependent dominance and this resolves a potential intra-locus sexual conflict in the species. The relatively simple genetic architecture of this trait combined with the features of Atlantic salmon as a model system offer an ideal opportunity to better understand the molecular mechanisms and ecological drivers underlying a locally adapted life history trait. In MATURATION I will i) characterize age at maturity candidate gene functions and allelic effects on phenotypes ii) elucidate fitness effects of these phenotypes and GxE interactions iii) develop a mechanistic model for the sex-dependent dominance and validate intra-locus sexual conflict resolution

 Publications

year authors and title journal last update
List of publications.
2019 Kenyon B. Mobley, Hanna Granroth-Wilding, Mikko Ellmen, Juha-Pekka Vähä, Tutku Aykanat, Susan E. Johnston, Panu Orell, Jaakko Erkinaro, Craig R. Primmer
Home ground advantage: Local Atlantic salmon have higher reproductive fitness than dispersers in the wild
published pages: eaav1112, ISSN: 2375-2548, DOI: 10.1126/sciadv.aav1112
Science Advances 5/2 2019-10-08
2018 Yann Czorlich, Tutku Aykanat, Jaakko Erkinaro, Panu Orell, Craig Robert Primmer
Rapid sex-specific evolution of age at maturity is shaped by genetic architecture in Atlantic salmon
published pages: 1800-1807, ISSN: 2397-334X, DOI: 10.1038/s41559-018-0681-5
Nature Ecology & Evolution 2/11 2019-10-08

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MATURATION" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MATURATION" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

evolSingleCellGRN (2019)

Constraint, Adaptation, and Heterogeneity: Genomic and single-cell approaches to understanding the evolution of developmental gene regulatory networks

Read More  

IMMUNOTHROMBOSIS (2019)

Cross-talk between platelets and immunity - implications for host homeostasis and defense

Read More  

RODRESET (2019)

Development of novel optogenetic approaches for improving vision in macular degeneration

Read More