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CITYCARE SIGNED

Impact of air pollutants on cutaneous responses in both healthy and compromised skin barrier, and innovative solutions to protect skin against urban pollution

Total Cost €

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EC-Contrib. €

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Partnership

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Project "CITYCARE" data sheet

The following table provides information about the project.

Coordinator
DOW SILICONES BELGIUM 

Organization address
address: RUE JULES BORDET PARC INDUSTRIEL ZONE C
city: SENEFFE
postcode: 7180
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Project website http://www.citycare-itn.eu
 Total cost 773˙848 €
 EC max contribution 773˙848 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-EID
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2021-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    DOW SILICONES BELGIUM BE (SENEFFE) coordinator 250˙560.00
2    UNIVERSITE DE FRIBOURG CH (FRIBOURG) participant 265˙226.00
3    UNIVERSITA DEGLI STUDI DI FERRARA IT (FERRARA) participant 258˙061.00
4    BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY US (STANFORD) partner 0.00

Map

 Project objective

Nowadays, our skin is increasingly more assaulted, as a result of the increasingly complexity of our living environment. Because of its critical location, the skin is continuously exposed not only to natural environmental stress factors, such as UV radiation, ozone and extreme weather conditions associated with climatic changes, but also to pollutants/aggressors of anthropic origin, such as cigarette smoke and diesel/gasoline fuel exhaust. By combining the complementary expertise of the three partners involved in the present consortium, i.e. polymer technology and formulation expertise (DCE), skin barrier understanding and biochemistry/molecular biology (UoF), and impact of diesel/gasoline exhaust on cellular responses (UNIFR), this project will aim (i) at better understanding the consequences of air pollutants on both skin integrity and function, (ii) at investigating the synergistic effects of air pollutants such as ozone, cigarette smoke and diesel exhaust with UV radiation, (iii) at discovering innovative solutions to protect skin against those environmental stressors using both a curative approach based on the optimization of the delivery and efficacy of antioxidant compounds, and a preventive approach, based on the formation of a polymeric barrier film at the skin surface, (iv) at studying the impact of air pollutants on both healthy skin and compromised, damaged skin since the number of individuals suffering from skin diseases such as atopic dermatitis and psoriasis continuously increases with the increasingly level of air pollution and air-conditioning systems. The variety of training offered under this EID proposal will enable three early-stage researchers to build strong S&T background as well as to develop numerous transferable skills for their future career. The present training program will allow the researchers to expand their knowledge to new domains and applications, while also providing good networking opportunities.

 Deliverables

List of deliverables.
\"Scientific publication ESR2 #1\" Other 2020-01-14 11:45:07
Inflammatory markers induced by ozone Documents, reports 2020-01-14 11:42:38
Impact of cigarette smoke in combination with UV radiation on cutaneous responses in both healthy and atopic skin models Documents, reports 2020-01-14 11:51:55
Advertisement of ESR position (including EURAXESS) Other 2020-01-14 11:45:05
inflammatory markers induced by cigarette smoke Documents, reports 2020-01-14 11:45:06
Cell culture models for assessing the toxicity induced by ozone Documents, reports 2020-01-14 11:45:11
Workshop on Cell Culture & Molecular Biology Other 2020-01-14 11:45:07
Impact of diesel/gasoline exhaust in combination with UV radiation on cutaneous responses in both healthy and atopic skin models Documents, reports 2020-01-14 11:46:47
inflammatory markers induced by diesel/gasoline exhaust Documents, reports 2020-01-14 11:42:37
Impact of ozone in combination with UV radiation on cutaneous responses in both healthy and atopic skin models Documents, reports 2020-01-14 11:42:36
\"Scientific publication ESR3 #1\" Other 2020-01-14 11:45:06
Cell culture models for assessing the toxicity induced by Cigarette smoke Documents, reports 2020-01-14 11:45:07
Cell culture models for assessing the toxicity induced by Diesel Exhaust Documents, reports 2020-01-14 11:42:37
\"Scientific publication ESR1 #1\" Other 2020-01-14 11:45:06

Take a look to the deliverables list in detail:  detailed list of CITYCARE deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 Roxane Prieux, Marc Eeman, Barbara Rothen-Rutishauser, Giuseppe Valacchi
Mimicking cigarette smoke exposure to assess cutaneous toxicity
published pages: 104664, ISSN: 0887-2333, DOI: 10.1016/j.tiv.2019.104664
Toxicology in Vitro 2019-11-07
2019 Alessandra Pecorelli, Brittany Woodby, Roxane Prieux, Giuseppe Valacchi
Involvement of 4‐hydroxy‐2‐nonenal in pollution‐induced skin damage
published pages: , ISSN: 0951-6433, DOI: 10.1002/biof.1513
BioFactors 2019-08-05

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The information about "CITYCARE" are provided by the European Opendata Portal: CORDIS opendata.

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