Explore the words cloud of the iNanoBIT project. It provides you a very rough idea of what is the project "iNanoBIT" about.
The following table provides information about the project.
Coordinator |
BIOTALENTUM TUDASFEJLESZTO KFT
Organization address contact info |
Coordinator Country | Hungary [HU] |
Project website | http://inanobit.eu/ |
Total cost | 6˙999˙997 € |
EC max contribution | 6˙999˙997 € (100%) |
Programme |
1. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies) |
Code Call | H2020-NMBP-2017-two-stage |
Funding Scheme | RIA |
Starting year | 2017 |
Duration (year-month-day) | from 2017-10-01 to 2022-09-30 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | BIOTALENTUM TUDASFEJLESZTO KFT | HU (GOEDOELLO) | coordinator | 1˙301˙341.00 |
2 | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN | DE (MUENCHEN) | participant | 1˙629˙575.00 |
3 | Mediso Orvosi Berendezes Fejleszto es Szerviz Kft. | HU (BUDAPEST) | participant | 795˙375.00 |
4 | BBS NANOTECHNOLOGIA KUTATASI ES FEJLESZTESI KORLATOLT FELELOSSEGU TARSASAG | HU (DEBRECEN) | participant | 710˙726.00 |
5 | UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA | IT (MILANO) | participant | 652˙563.00 |
6 | DEFYMED | FR (STRASBOURG) | participant | 645˙625.00 |
7 | ITHERA MEDICAL GMBH | DE (MUNCHEN) | participant | 636˙041.00 |
8 | UNIVERSITE CATHOLIQUE DE LOUVAIN | BE (LOUVAIN LA NEUVE) | participant | 628˙750.00 |
The iNanoBIT project is aimed to apply nanotechnologies for imaging porcine pancreatic islet cellular transplants and induced pluripotent stem cell-derived beta-cells and subsequent regenerative processes in vivo in a porcine model. The project will develop1) novel highly sensitive nanotechnology-based imaging approaches allowing for monitoring of survival, engraftment, proliferation, function and whole body distribution of the cellular transplants in a preclinical porcine model with excellent translational potential to humans; 2) develop and validate the application of state-of-the-art imaging technologies facilitating the provision of new regenerative therapies to preclinical large animal models and patients; 3) directly contribute to the opening of a new market sector for i) imaging equipment (SPECT, PET/MR, optoacoustic imaging in preclinical large animal models and patients), ii) nano-imaging molecule supplies (nanomolecules allowing multimodality imaging of specific cell types with high sensitivity), iii) validated transplantable in vitro differentiated human beta-cells and porcinexenotransplant islets thus will reinforce the European healthcare supply chain for regenerative medicinal products. The iNanoBIT project will provide the currently missing toolbox for preclinical/clinical testing for a safe translation of regenerative medicinal cellular and tissue products, currently under preclinical and clinical trials, which is vital for the competitiveness of the European healthcare sector in this fast-growing area. The consortium of 5 SME and 3 Academic partners is coordinated and driven by the industrial partners from the field of nanotechnology, imaging and stem cell technologies, providing a perfect match and unique combination addressing the scope and expected impact of the call and providing TRL 3/4 starting points for the key technological elements, and expect to arrive to TRL6 levels of validated technologies ready for marketing by the end of the project.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
Elisabeth Kemter, Eckhard Wolf Recent progress in porcine islet isolation, culture and engraftment strategies for xenotransplantation published pages: 1, ISSN: 1087-2418, DOI: 10.1097/mot.0000000000000579 |
Current Opinion in Organ Transplantation | 2019-10-30 |
2018 |
Elisabeth Kemter, Joachim Denner, Eckhard Wolf Will Genetic Engineering Carry Xenotransplantation of Pig Islets to the Clinic? published pages: , ISSN: 1534-4827, DOI: 10.1007/s11892-018-1074-5 |
Current Diabetes Reports 18/11 | 2019-10-30 |
2019 |
Susanna Sampaolesi, Francesco Nicotra, Laura Russo Glycans in nanomedicine, impact and perspectives published pages: 43-60, ISSN: 1756-8919, DOI: 10.4155/fmc-2018-0368 |
Future Medicinal Chemistry 11/1 | 2019-10-30 |
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The information about "INANOBIT" are provided by the European Opendata Portal: CORDIS opendata.
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