Explore the words cloud of the iNanoBIT project. It provides you a very rough idea of what is the project "iNanoBIT" about.
The following table provides information about the project.
BIOTALENTUM TUDASFEJLESZTO KFT
|Coordinator Country||Hungary [HU]|
|Total cost||6˙999˙997 €|
|EC max contribution||6˙999˙997 € (100%)|
1. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
|Duration (year-month-day)||from 2017-10-01 to 2022-09-30|
Take a look of project's partnership.
|1||BIOTALENTUM TUDASFEJLESZTO KFT||HU (GOEDOELLO)||coordinator||1˙301˙341.00|
|2||LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN||DE (MUENCHEN)||participant||1˙629˙575.00|
|3||Mediso Orvosi Berendezes Fejleszto es Szerviz Kft.||HU (BUDAPEST)||participant||795˙375.00|
|4||BBS NANOTECHNOLOGIA KUTATASI ES FEJLESZTESI KORLATOLT FELELOSSEGU TARSASAG||HU (DEBRECEN)||participant||710˙726.00|
|5||UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA||IT (MILANO)||participant||652˙563.00|
|7||ITHERA MEDICAL GMBH||DE (MUNCHEN)||participant||636˙041.00|
|8||UNIVERSITE CATHOLIQUE DE LOUVAIN||BE (LOUVAIN LA NEUVE)||participant||628˙750.00|
The iNanoBIT project is aimed to apply nanotechnologies for imaging porcine pancreatic islet cellular transplants and induced pluripotent stem cell-derived beta-cells and subsequent regenerative processes in vivo in a porcine model. The project will develop1) novel highly sensitive nanotechnology-based imaging approaches allowing for monitoring of survival, engraftment, proliferation, function and whole body distribution of the cellular transplants in a preclinical porcine model with excellent translational potential to humans; 2) develop and validate the application of state-of-the-art imaging technologies facilitating the provision of new regenerative therapies to preclinical large animal models and patients; 3) directly contribute to the opening of a new market sector for i) imaging equipment (SPECT, PET/MR, optoacoustic imaging in preclinical large animal models and patients), ii) nano-imaging molecule supplies (nanomolecules allowing multimodality imaging of specific cell types with high sensitivity), iii) validated transplantable in vitro differentiated human beta-cells and porcinexenotransplant islets thus will reinforce the European healthcare supply chain for regenerative medicinal products. The iNanoBIT project will provide the currently missing toolbox for preclinical/clinical testing for a safe translation of regenerative medicinal cellular and tissue products, currently under preclinical and clinical trials, which is vital for the competitiveness of the European healthcare sector in this fast-growing area. The consortium of 5 SME and 3 Academic partners is coordinated and driven by the industrial partners from the field of nanotechnology, imaging and stem cell technologies, providing a perfect match and unique combination addressing the scope and expected impact of the call and providing TRL 3/4 starting points for the key technological elements, and expect to arrive to TRL6 levels of validated technologies ready for marketing by the end of the project.
|year||authors and title||journal||last update|
Elisabeth Kemter, Eckhard Wolf
Recent progress in porcine islet isolation, culture and engraftment strategies for xenotransplantation
published pages: 1, ISSN: 1087-2418, DOI: 10.1097/mot.0000000000000579
|Current Opinion in Organ Transplantation||2019-10-30|
Elisabeth Kemter, Joachim Denner, Eckhard Wolf
Will Genetic Engineering Carry Xenotransplantation of Pig Islets to the Clinic?
published pages: , ISSN: 1534-4827, DOI: 10.1007/s11892-018-1074-5
|Current Diabetes Reports 18/11||2019-10-30|
Susanna Sampaolesi, Francesco Nicotra, Laura Russo
Glycans in nanomedicine, impact and perspectives
published pages: 43-60, ISSN: 1756-8919, DOI: 10.4155/fmc-2018-0368
|Future Medicinal Chemistry 11/1||2019-10-30|
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The information about "INANOBIT" are provided by the European Opendata Portal: CORDIS opendata.
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