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EPIDEMICSonCHIP SIGNED

EPIDEMICS in ant societies ON a CHIP

Total Cost €

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EC-Contrib. €

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Partnership

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 EPIDEMICSonCHIP project word cloud

Explore the words cloud of the EPIDEMICSonCHIP project. It provides you a very rough idea of what is the project "EPIDEMICSonCHIP" about.

individually    infection    evolution    queens    limit    defence    hosts    interaction    observe    reproductive    epidemics    group    subset    amplifies    insect    generation    single    majority    care    society    sanitary    replicate    form    techniques    automatised    defences    sick    living    behavioural    correlational    manipulate    organisational    poorly    host    males    emerges    dense    synergise    pathogen    networks    read    platform    experiments    collective    quantified    turn    chip    individual    quantity    effect    lab    societies    behaviours    ant    arbitrarily    shapes    workers    members    interactions    easily    pathogens    epidemic    quality    develops    fungal    powerful    social    disease    manipulative    modeling    structure    quantify    fitness    offspring    experimental    colony    protection    spatiotemporal    surveillance    risk    engineer    combine    initial    principles    monitor    immunity    productivity    accessible    entity    sterile    infer    spread    individuals   

Project "EPIDEMICSonCHIP" data sheet

The following table provides information about the project.

Coordinator
INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA 

Organization address
address: Am Campus 1
city: KLOSTERNEUBURG
postcode: 3400
website: www.ist.ac.at

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Austria [AT]
 Project website https://socialimmunity.com/funding/erc-consolidator-grant-2017
 Total cost 1˙991˙564 €
 EC max contribution 1˙991˙564 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-04-01   to  2023-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA AT (KLOSTERNEUBURG) coordinator 1˙991˙564.00

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 Project objective

Living in societies amplifies the risk of getting sick, as pathogens can easily spread along the dense social interaction networks of the hosts. Sanitary care and the organisational structure of societies are expected to limit the risk of epidemics. Yet, how the defences of the individual group members scale-up, combine and synergise towards society-level protection, is poorly understood, as the majority of societies can only be studied via correlational and modeling approaches. Insect societies provide a powerful system for experimental studies, as whole societies are accessible for surveillance and manipulative approaches. We can monitor every behavioural interaction between all members, determine their effects on colony-wide disease spread and replicate experiments arbitrarily. The fitness effects of collective disease defences can be quantified, as they result in a single fitness measure of colony productivity. This is because all members of a social insect colony form a reproductive entity composed of the reproductive queens and males and their sterile workers. I will use an ant host–fungal pathogen system to find out how initial infection develops into an epidemic, and, in turn, how colony-level defence emerges from the interactions between its members. To infer effect from cause, I will not only observe the colony after initial infection of a subset of colony members, but also manipulate the sanitary behaviours and spatiotemporal interaction of host individuals. To this end, I will engineer an automatised platform, following the principles of lab-on-a-chip techniques, to individually target and manipulate colony members, and to quantify their behaviours. Fitness effects will be read out by the quantity and quality of reproductive offspring in the next generation. Such a long-term whole-colony approach is required for understanding the evolution of social immunity, that is, how disease shapes society and how society shapes disease.

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