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HINBOTS SIGNED

Highly Integrated Nanoscale Robots for Targeted Delivery to the Central Nervous System

Total Cost €

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EC-Contrib. €

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Partnership

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 HINBOTS project word cloud

Explore the words cloud of the HINBOTS project. It provides you a very rough idea of what is the project "HINBOTS" about.

remotely    reduce    payloads    decades    chassis    surface    myriad    structures    release    entities    molecular    loaded    act    power    gated    electrostimulating    magnetic    risk    over    synthetic    realizing    sources    piezoelectrochemical    materials    demonstrated    environments    gates    multiferroics    harvesting    ultimately    sought    magnetoelectric    surrounding    onto    nanorobots    machinery    machines    robots    integrate    navigate    electroresponsive    inorganic    ranging    central    sites    external    platforms    create    animal    ultimate    time    multiferroic    conventional    demand    smart    rewiring    first    interventions    moving    assemblies    chemistry    piezoelectric    neural    circuitry    functions    host    perform    supramolecular    nanomaterials    miniaturized    grafted    invasive    cargo    fuel    therapeutic    nervous    minimally    consists    redox    media    triggered    robotics    theatre    acoustic    delivering    active    agents    models    made    multifunctional    porous    micro    discomfort    capitalizing    small   

Project "HINBOTS" data sheet

The following table provides information about the project.

Coordinator
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH 

Organization address
address: Raemistrasse 101
city: ZUERICH
postcode: 8092
website: https://www.ethz.ch/de.html

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 1˙998˙720 €
 EC max contribution 1˙998˙720 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2017-COG
 Funding Scheme ERC-COG
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2023-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) coordinator 1˙998˙720.00

Map

 Project objective

Over the past two decades researchers have been working to create synthetic small-scale machines ranging from molecular entities or miniaturized structures, to more complex assemblies of micro- and nanomaterials. These machines are able to navigate in complex environments by harvesting fuel from the surrounding media or from external power sources. One of the most sought-after applications for these miniaturized machines is to perform minimally invasive interventions, in which these devices will ultimately reduce risk, cost, and discomfort compared to conventional interventions. This has driven researchers to produce a myriad of small-scale robots loaded with therapeutic cargo. While recent research has demonstrated the potential of these devices in animal models, a number of challenges remain in moving small-scale robots into the operating theatre. Here, we propose highly integrated nanorobots capable of realizing several functions on-demand by capitalizing on recent developments in small-scale robotics, multiferroics, supramolecular chemistry, and gated materials. These nanorobots will integrate a porous inorganic active chassis made of a piezoelectric or a magnetoelectric multiferroic that will host therapeutic agents, with redox or electroresponsive supramolecular gates that will control the release of payloads. We will demonstrate for the first time that redox- and electroresponsive supramolecular machinery grafted onto the surface of piezoelectric or multiferroic platforms can be remotely controlled by means of a piezoelectrochemical potential triggered by acoustic and magnetic fields. The ultimate goal of this research consists of creating smart multifunctional nanorobots, which will act on affected sites of the central nervous system by delivering therapeutic agents and electrostimulating the rewiring of neural circuitry.

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The information about "HINBOTS" are provided by the European Opendata Portal: CORDIS opendata.

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