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HepaCheC SIGNED

HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 HepaCheC project word cloud

Explore the words cloud of the HepaCheC project. It provides you a very rough idea of what is the project "HepaCheC" about.

glycoprotein    healthy    glycobond    business    accelerated    months    peptide    place    invasive    protocols    death    diagnosed    certain    stage    lifestyle    mainly    laboratory    size    agp    mono    hcc    inadequate    survival    epidemic    biomarker    antibody    alpha    hepatitis    western    japan    chances    constitutes    workflow    easily    hepachec    tumours    requiring    competitiveness    dependant    eminent    world    assay    minimally    blood    discover    methodology    decreasing    grown    commercial    hepatocellular    solid    detection    patients    fucosylated    detects    elementary    acid    launch    median    plan    merely    combination    vitro    obesity    diagnosis    patented    monitor    house    surveillance    incorporated    ultrasound    specificity    infections    followed    polyclonal    performed    standardized    liver    shallow    company    relatively    elisa    costly    guidelines    validation    carcinoma    successful    correlates    cancer    risk    clinical    diagnostic    selectivity    standard    ed    worldwide    10    international   

Project "HepaCheC" data sheet

The following table provides information about the project.

Coordinator
GLYCOBOND AB 

Organization address
address: TEKNIKRINGEN 1 F
city: LINKOPING
postcode: 583 30
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://glycobond.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-02-01   to  2018-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    GLYCOBOND AB SE (LINKOPING) coordinator 50˙000.00

Map

 Project objective

The objective of this project is to develop a business plan for the clinical validation and commercial launch of HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer (hepatocellular carcinoma (HCC)).

Current diagnostic methods (mainly ultrasound) are inadequate due to not being specific enough, being user-dependant, costly and only able to discover relatively shallow tumours that have grown to a certain size.

The HepaCheC assay, on the other hand, is a minimally invasive method (requiring a blood sample) with high selectivity and specificity that detects a specific liver cancer biomarker; fucosylated AGP (α1-acid glycoprotein). Glycobond’s patented Mono-F peptide constitutes the solid phase of the HepaCheC assay, followed by an in-house developed polyclonal AGP-specific antibody. The assay is based on the ELISA methodology, making it easily incorporated into the workflow of any standard diagnostic/research laboratory requiring only elementary laboratory know-how to be performed.

HCC is one of the leading cause of cancer death worldwide. Currently, only 10% of all HCC cases are diagnosed at an early stage, which directly correlates to decreasing chances of survival: the current median survival is merely 6-20 months following diagnosis. HCC is on the rise in the Western world due to a combination of an increase in Hepatitis B and C infections and our less healthy lifestyle that has resulted in an obesity epidemic. There is therefore an eminent need to improve standardized detection protocols.

The goal of Glycobond is to make HepaCheC part of the existing surveillance guidelines that are in place to monitor high-risk patients in the EU, US and Japan. If successful, the company will increase its international competitiveness and experience accelerated growth.

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The information about "HEPACHEC" are provided by the European Opendata Portal: CORDIS opendata.

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