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HepaCheC SIGNED

HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 HepaCheC project word cloud

Explore the words cloud of the HepaCheC project. It provides you a very rough idea of what is the project "HepaCheC" about.

stage    liver    incorporated    alpha    plan    peptide    monitor    biomarker    blood    glycobond    guidelines    clinical    hcc    worldwide    10    death    diagnostic    standard    ed    risk    acid    agp    antibody    commercial    tumours    patented    requiring    elisa    japan    fucosylated    vitro    glycoprotein    workflow    followed    carcinoma    assay    ultrasound    mainly    obesity    size    correlates    discover    combination    survival    standardized    accelerated    competitiveness    specificity    solid    international    hepachec    detection    invasive    eminent    diagnosis    business    hepatocellular    western    elementary    merely    detects    easily    shallow    inadequate    diagnosed    selectivity    constitutes    polyclonal    cancer    protocols    grown    lifestyle    place    patients    certain    healthy    world    methodology    launch    months    decreasing    infections    median    mono    dependant    surveillance    house    performed    minimally    chances    relatively    validation    successful    epidemic    laboratory    costly    company    hepatitis   

Project "HepaCheC" data sheet

The following table provides information about the project.

Coordinator
GLYCOBOND AB 

Organization address
address: TEKNIKRINGEN 1 F
city: LINKOPING
postcode: 583 30
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://glycobond.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-02-01   to  2018-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    GLYCOBOND AB SE (LINKOPING) coordinator 50˙000.00

Map

 Project objective

The objective of this project is to develop a business plan for the clinical validation and commercial launch of HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer (hepatocellular carcinoma (HCC)).

Current diagnostic methods (mainly ultrasound) are inadequate due to not being specific enough, being user-dependant, costly and only able to discover relatively shallow tumours that have grown to a certain size.

The HepaCheC assay, on the other hand, is a minimally invasive method (requiring a blood sample) with high selectivity and specificity that detects a specific liver cancer biomarker; fucosylated AGP (α1-acid glycoprotein). Glycobond’s patented Mono-F peptide constitutes the solid phase of the HepaCheC assay, followed by an in-house developed polyclonal AGP-specific antibody. The assay is based on the ELISA methodology, making it easily incorporated into the workflow of any standard diagnostic/research laboratory requiring only elementary laboratory know-how to be performed.

HCC is one of the leading cause of cancer death worldwide. Currently, only 10% of all HCC cases are diagnosed at an early stage, which directly correlates to decreasing chances of survival: the current median survival is merely 6-20 months following diagnosis. HCC is on the rise in the Western world due to a combination of an increase in Hepatitis B and C infections and our less healthy lifestyle that has resulted in an obesity epidemic. There is therefore an eminent need to improve standardized detection protocols.

The goal of Glycobond is to make HepaCheC part of the existing surveillance guidelines that are in place to monitor high-risk patients in the EU, US and Japan. If successful, the company will increase its international competitiveness and experience accelerated growth.

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The information about "HEPACHEC" are provided by the European Opendata Portal: CORDIS opendata.

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