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HepaCheC SIGNED

HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 HepaCheC project word cloud

Explore the words cloud of the HepaCheC project. It provides you a very rough idea of what is the project "HepaCheC" about.

hepatitis    stage    workflow    fucosylated    validation    assay    patients    incorporated    constitutes    selectivity    dependant    costly    guidelines    performed    accelerated    liver    hcc    standard    biomarker    tumours    easily    plan    merely    glycobond    certain    international    discover    requiring    blood    diagnostic    followed    peptide    western    risk    mainly    obesity    cancer    infections    laboratory    world    10    inadequate    solid    diagnosed    standardized    invasive    hepachec    carcinoma    hepatocellular    competitiveness    detects    decreasing    glycoprotein    correlates    japan    acid    elisa    polyclonal    survival    size    commercial    eminent    minimally    monitor    death    grown    protocols    ultrasound    alpha    vitro    business    lifestyle    agp    surveillance    combination    relatively    company    diagnosis    worldwide    median    house    mono    elementary    place    specificity    healthy    antibody    detection    ed    shallow    chances    clinical    successful    methodology    launch    patented    epidemic    months   

Project "HepaCheC" data sheet

The following table provides information about the project.

Coordinator
GLYCOBOND AB 

Organization address
address: TEKNIKRINGEN 1 F
city: LINKOPING
postcode: 583 30
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Project website http://glycobond.com/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology)
2. H2020-EU.2.3.1. (Mainstreaming SME support, especially through a dedicated instrument)
 Code Call H2020-SMEINST-1-2016-2017
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-02-01   to  2018-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    GLYCOBOND AB SE (LINKOPING) coordinator 50˙000.00

Map

 Project objective

The objective of this project is to develop a business plan for the clinical validation and commercial launch of HepaCheC - an in vitro diagnostic assay for the early detection of liver cancer (hepatocellular carcinoma (HCC)).

Current diagnostic methods (mainly ultrasound) are inadequate due to not being specific enough, being user-dependant, costly and only able to discover relatively shallow tumours that have grown to a certain size.

The HepaCheC assay, on the other hand, is a minimally invasive method (requiring a blood sample) with high selectivity and specificity that detects a specific liver cancer biomarker; fucosylated AGP (α1-acid glycoprotein). Glycobond’s patented Mono-F peptide constitutes the solid phase of the HepaCheC assay, followed by an in-house developed polyclonal AGP-specific antibody. The assay is based on the ELISA methodology, making it easily incorporated into the workflow of any standard diagnostic/research laboratory requiring only elementary laboratory know-how to be performed.

HCC is one of the leading cause of cancer death worldwide. Currently, only 10% of all HCC cases are diagnosed at an early stage, which directly correlates to decreasing chances of survival: the current median survival is merely 6-20 months following diagnosis. HCC is on the rise in the Western world due to a combination of an increase in Hepatitis B and C infections and our less healthy lifestyle that has resulted in an obesity epidemic. There is therefore an eminent need to improve standardized detection protocols.

The goal of Glycobond is to make HepaCheC part of the existing surveillance guidelines that are in place to monitor high-risk patients in the EU, US and Japan. If successful, the company will increase its international competitiveness and experience accelerated growth.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "HEPACHEC" project.

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The information about "HEPACHEC" are provided by the European Opendata Portal: CORDIS opendata.

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