Opendata, web and dolomites


Discovering functional protein-RNA interactions through data integration and machine learning.

Total Cost €


EC-Contrib. €






 DeepRNA project word cloud

Explore the words cloud of the DeepRNA project. It provides you a very rough idea of what is the project "DeepRNA" about.

fellowship    variants    validating    partitioning    record    blackfan    interactions    life    host    threatening    translation    accuracy    independence    am    encoding    interaction    determined    anaemia    transcriptome    molecular    thereby    heterogeneous    352    creatively    loci    experimental    recognised    trait    experimentally    defects    als    associations    globally    polymorphisms    diseases    proteins    binding    maintaining    deeprna    skills    me    medically    diamond    dataset    group    amyotrophic    personalised    interdisciplinary    complementing    aiding    signalling    network    genetic    gold    genome    human    data    complemented    tools    expression    542    expand    confident    standard    transferrable    rna    graph    protein    ataxia    domain    mechanisms    rnas    quantitative    interactome    quality    medicine    disease    track    equip    neural    team    enabled    computing    ranging    lateral    examples    rationalise    predictions    sclerosis    spinocerebellar    splicing    spectrum    eqtls    manner    aggregation    implicated    genomic    confidently    eqtl    disorders    employ   

Project "DeepRNA" data sheet

The following table provides information about the project.


Organization address
postcode: 8003

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 158˙121 €
 EC max contribution 158˙121 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2018
 Duration (year-month-day) from 2018-03-01   to  2020-02-29


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

RNA-binding proteins are implicated across a wide spectrum of human genetic disorders, with molecular mechanisms ranging from aggregation of proteins and RNAs to defects in splicing and translation. Examples include heterogeneous and life-threatening genetic disorders such as Diamond-Blackfan anaemia, spinocerebellar ataxia and amyotrophic lateral sclerosis (ALS) among others.

The DeepRNA project targets genetic diseases via disease-associated variants in the human transcriptome and is enabled by recent data on expression quantitative trait loci (eQTLs) and experimentally determined RNA-protein and RNA-RNA interactions. The data will be complemented with high-quality RNA-protein interaction predictions carried out in the host group that has a strong track record in computing and validating RNA-protein associations.

To my knowledge the use of eQTL variants to study RNA-protein interactions is a novel approach and is useful for developing new tools for personalised medicine. My approach will expand the human interactome in a genome-wide manner beyond experimental data, which is currently available for only 352 of the 1,542 recently described RNA-binding proteins. Complementing experimentally determined interactions with predictions will allow me to expand my analyses of the human interactome to the genomic scale while maintaining accuracy, by using the experimental dataset as a gold standard. I will employ methods such as graph partitioning and graph neural network encoding to rationalise the effects of disease-associated variants on the human interaction network, and make quantitative predictions of polymorphisms associated with genetic diseases, thereby aiding personalised medicine.

I am confident that this fellowship will equip me with the domain knowledge, independence and transferrable skills to confidently and creatively build an interdisciplinary, globally recognised research team within Europe that will focus on medically relevant human signalling systems.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DEEPRNA" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email ( and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "DEEPRNA" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

MCRD (2020)

Development Of Microfluidic Based Low Cost Industrial Cryo-Ready Devices For Preservation Of Living Cells

Read More  

EuroDipl (2020)

European Diplomacy Practices post-Lisbon: Adding Value through Cooperation

Read More  


Photodynamic therapy enabled DNA-fork-binding metallo-cylinders: drugs and release triggers

Read More