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SOUNDSCENE SIGNED

How does the brain organize sounds into auditory scenes?

Total Cost €

EC-Contrib. €

Partnership

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SOUNDSCENE project word cloud

Explore the words cloud of the SOUNDSCENE project. It provides you a very rough idea of what is the project "SOUNDSCENE" about.

competing manipulate channel cell hearing operate unknown negatively single sound conjunction models waveform listening cortex arrives appropriately hippocampus world area noisy electrophysiological circuit record imaging real computational underpins regions ease neuronal normal perceptual aging sources healthy engage attentional listen solves combine strategies scene perceived guide little exist neuro composite highlight provides count behavioural reconstruct cellular recordings listeners networks understand elucidate active prefrontal paradigm barrier organizes recreate critical faced young manipulation interactions mixture impairments optogenetic auditory rehabilitative mechanisms inability animal brain digital parse neural network sense functional situations central advancing humans ear

Project "SOUNDSCENE" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	1˙999˙999 €
EC max contribution	1˙999˙999 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2017-COG
Funding Scheme	ERC-COG
Starting year	2018
Duration (year-month-day)	from 2018-09-01 to 2023-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	coordinator	1˙999˙999.00

Map

Project objective

Real-world listening involves making sense of the numerous competing sound sources that exist around us. The neuro-computational challenge faced by the brain is to reconstruct these sources from the composite waveform that arrives at the ear; a process known as auditory scene analysis. While young normal hearing listeners can parse an auditory scene with ease, the neural mechanisms that allow the brain to do this are unknown – and we are not yet able to recreate them with digital technology. Hearing loss, aging, impairments in central auditory processing, or an inability to appropriately engage attentional mechanisms can negatively impact the ability to listen in complex and noisy situations and an understanding of how the healthy brain organizes a sound mixture into perceptual sources may guide rehabilitative strategies targeting these problems.

While functional imaging studies in humans highlight a network of brain regions that support auditory scene analysis, little is known about the cellular and circuit based mechanisms that operate within these brain networks. A critical barrier to advancing our understanding of how the brain solves the challenge of scene analysis has been a failure to combine behavioural testing, which provides a crucial measure of how any given sound mixture is perceived, with methods to record and manipulate neuronal activity in animal models. Here, I propose to use a novel behavioural paradigm in conjunction with high-channel count electrophysiological recordings and optogenetic manipulation to elucidate how auditory cortex, prefrontal cortex and hippocampus enable scene analysis during active listening. These methods will allow us to record single cell activity from a number of brain regions more typical of functional imaging studies in order to understand how processing within each area, and the interactions between these areas, underpins auditory scene analysis.

Deliverables

List of deliverables.
Data Management Plan	Open Research Data Pilot	2019-10-03 18:12:33

Take a look to the deliverables list in detail: detailed list of SOUNDSCENE deliverables.

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The information about "SOUNDSCENE" are provided by the European Opendata Portal: CORDIS opendata.