Explore the words cloud of the NewBorN project. It provides you a very rough idea of what is the project "NewBorN" about.
The following table provides information about the project.
UNIVERSITY OF BRISTOL
|Coordinator Country||United Kingdom [UK]|
|Total cost||195˙454 €|
|EC max contribution||195˙454 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2018-07-31 to 2020-07-30|
Take a look of project's partnership.
|1||UNIVERSITY OF BRISTOL||UK (BRISTOL)||coordinator||195˙454.00|
In the past decade, photoredox catalysis has emerged as a tremendously versatile process to generate reactive radical species in organic synthesis under very mild conditions. Meanwhile, the host group have developed a suite of transformations exploiting the fundamental chemistry of boron, many of which involve 1,2-metallate rearrangement of boronate complexes. In this proposal, we propose to merge the N-centred radicals generated through photoredox catalysis and 1,2-metallate rearrangements of vinyl boronate complexes to create an efficient new strategy for organic synthesis, which will lead to a novel three component reaction where new C–C and C–N bonds are formed in one-pot, providing a new synthetic avenue for the preparation of β-amino boronic esters. Moreover, intramolecular radical cyclizations followed by oxidative 1,2-migration will enable the stereoselective synthesis of diversely functionalized cyclic amines. The scope of these processes will be carefully investigated, and mechanistic studies will be carried out using advanced physical/chemical methods. These novel methodologies not only benefit from the formation of highly functionalized products bearing both synthetically versatile boronic ester and amino moieties, but also lay solid foundations for the development of this new field. Based on the significant antibacterial activity against Mycobacterium tuberculosis of β-amino boronic acids, a preliminary test of the biological activities of compounds obtained throughout the proposed research (both cyclic and linear β-amino-boronic acids) will be carried out in collaboration with AstraZeneca. By combining two major fields of endeavour, new chemistry will emerge with unique structures harbouring novel properties for exploitation. Furthermore this project will enable significant knowledge transfer between host and researcher, while forging new academic networks within the scientific community.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NEWBORN" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "NEWBORN" are provided by the European Opendata Portal: CORDIS opendata.
The PIDE and Portuguese Society under the Salazar Dictatorship 1945-1974: Fear, Self-Policing, Accommodation.Read More
Quality of Service for the Internet of Things in Smart Cities via Predictive NetworksRead More
Ethnic geography and civil conflictRead More