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SiPoMorph SIGNED

Genetic control and molecular mechanisms of cell wall modifications during sieve pore morphogenesis in the phloem of the plant vascular system

Total Cost €

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EC-Contrib. €

0

Partnership

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 SiPoMorph project word cloud

Explore the words cloud of the SiPoMorph project. It provides you a very rough idea of what is the project "SiPoMorph" about.

tissues    lab    livestock    sink    connect    flow    dominant    largely    continuous    passed    knock    nearly    deposition    mutants    surprisingly    adaptive    conductive    transgenic    mechanisms    lines    molecular    organs    pores    localized    additionally    genetic    poorly    modern    mechanistic    host    biological    supra    proteins    tubes    morphogenesis    hormones    mediated    pore    mostly    hence    plant    equally    occlusion    tools    xylem    vasculature    point    fundamental    candidate    abiotic    phloem    agriculture    players    efficient    stresses    infections    ablation    unknown    callose    encoding    source    crispr    developmental    stress    lacking    critical    form    plates    science    damage    degradation    rnas    tubers    units    cellular    roots    functionally    sap    inducible    morphological    powerful    interference    describe    adaptations    sugars    cells    seeds    cell    fruits    variances    leaves    larger    plate    perforation    calories    modulated    sieve    framework    laser    conducting    genes    humans    individual    differentiation    closed    transport   

Project "SiPoMorph" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2021-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 183˙454.00

Map

 Project objective

The plant vasculature comprises the xylem and phloem. The phloem’s conductive cells, the sieve elements, transport sugars produced in leaves to sink organs, such as roots, tubers, fruits and seeds. They also transport hormones and RNAs throughout the plant, enabling its adaptive and continuous development. Individual sieve elements connect through callose-rich sieve plates to form sieve tubes, the larger supra-cellular conducting units. Perforation of the sieve plate with sieve pores is critical to efficient sap flow and can be modulated by callose-mediated occlusion. Indeed, sieve pores are rapidly closed in response to tissues damage, abiotic stresses and infections. Cellular differentiation and adaptation of sieve elements, particularly sieve pore morphogenesis, are surprisingly poorly understood and, lacking powerful cell-biological tools, has largely been neglected. This project sets out to describe a molecular and genetic framework for sieve plate formation. To this end, mutants and transgenic lines already generated in the host lab will be characterized. Additionally, candidate genes, encoding mostly for unknown proteins will be localized in sieve elements. These genes will be functionally characterized using several state-of-the-art methods and specifically-tailored molecular tools, such as inducible CRISPR knock-out, laser ablation and dominant cell-specific genetic interference. This will identify novel molecular players during callose deposition and degradation at sieve pores and advance our mechanistic understanding of sieve plate formation and possible adaptive mechanisms of stress response. Morphological variances and developmental adaptations of sieve pores are important for phloem source-to-sink transport and nearly all calories consumed by humans and livestock have at some point passed through sieve pores. Hence, understanding their morphogenesis at the molecular level is equally relevant for fundamental plant science as for modern agriculture.

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The information about "SIPOMORPH" are provided by the European Opendata Portal: CORDIS opendata.

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