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SiPoMorph SIGNED

Genetic control and molecular mechanisms of cell wall modifications during sieve pore morphogenesis in the phloem of the plant vascular system

Total Cost €

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EC-Contrib. €

0

Partnership

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 SiPoMorph project word cloud

Explore the words cloud of the SiPoMorph project. It provides you a very rough idea of what is the project "SiPoMorph" about.

poorly    inducible    science    sieve    sugars    phloem    genes    individual    leaves    largely    lab    sap    livestock    adaptive    critical    host    players    plates    stresses    continuous    point    variances    ablation    framework    tubes    larger    pore    tools    lines    roots    mechanisms    transport    laser    closed    mostly    unknown    differentiation    form    seeds    efficient    passed    pores    morphogenesis    conductive    cells    cellular    flow    deposition    developmental    additionally    plant    source    organs    mediated    plate    molecular    agriculture    encoding    degradation    proteins    units    supra    describe    sink    nearly    occlusion    stress    vasculature    fruits    abiotic    functionally    fundamental    surprisingly    interference    dominant    localized    perforation    biological    candidate    morphological    connect    modern    humans    powerful    adaptations    mechanistic    callose    tissues    knock    hormones    cell    mutants    modulated    damage    equally    crispr    rnas    infections    transgenic    calories    tubers    xylem    genetic    lacking    hence    conducting   

Project "SiPoMorph" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2021-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 183˙454.00

Map

 Project objective

The plant vasculature comprises the xylem and phloem. The phloem’s conductive cells, the sieve elements, transport sugars produced in leaves to sink organs, such as roots, tubers, fruits and seeds. They also transport hormones and RNAs throughout the plant, enabling its adaptive and continuous development. Individual sieve elements connect through callose-rich sieve plates to form sieve tubes, the larger supra-cellular conducting units. Perforation of the sieve plate with sieve pores is critical to efficient sap flow and can be modulated by callose-mediated occlusion. Indeed, sieve pores are rapidly closed in response to tissues damage, abiotic stresses and infections. Cellular differentiation and adaptation of sieve elements, particularly sieve pore morphogenesis, are surprisingly poorly understood and, lacking powerful cell-biological tools, has largely been neglected. This project sets out to describe a molecular and genetic framework for sieve plate formation. To this end, mutants and transgenic lines already generated in the host lab will be characterized. Additionally, candidate genes, encoding mostly for unknown proteins will be localized in sieve elements. These genes will be functionally characterized using several state-of-the-art methods and specifically-tailored molecular tools, such as inducible CRISPR knock-out, laser ablation and dominant cell-specific genetic interference. This will identify novel molecular players during callose deposition and degradation at sieve pores and advance our mechanistic understanding of sieve plate formation and possible adaptive mechanisms of stress response. Morphological variances and developmental adaptations of sieve pores are important for phloem source-to-sink transport and nearly all calories consumed by humans and livestock have at some point passed through sieve pores. Hence, understanding their morphogenesis at the molecular level is equally relevant for fundamental plant science as for modern agriculture.

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The information about "SIPOMORPH" are provided by the European Opendata Portal: CORDIS opendata.

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