Opendata, web and dolomites

simpetmr SIGNED

Development of quantification procedures for simultaneous PET-MR data for human brain imaging

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 simpetmr project word cloud

Explore the words cloud of the simpetmr project. It provides you a very rough idea of what is the project "simpetmr" about.

imaging    signals    brain    provides    serve    drug    data    pet    mr    tools    interventions    modeling    simultaneous    fmri    quantification    possibility   

Project "simpetmr" data sheet

The following table provides information about the project.

Coordinator
REGION HOVEDSTADEN 

Organization address
address: KONGENS VAENGE 2
city: HILLEROD
postcode: 3400
website: www.regionh.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 212˙194 €
 EC max contribution 212˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2017
 Funding Scheme /MSCA-IF-EF-SE
 Starting year 2018
 Duration (year-month-day) from 2018-05-01   to  2020-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    REGION HOVEDSTADEN DK (HILLEROD) coordinator 212˙194.00

Mappa

 Project objective

Imaging of physiological functions in the living brain provides a unique possibility to study biological processes during disease or drug interventions. Functional magnetic resonance imaging (fMRI) and Positron Emission Tomography (PET) are important tools that enable brain imaging. Whereas PET enables determination of molecular target densities, fMRI provides information about brain hemodynamic responses to, e.g., a drug intervention.

There are several research questions where the synergy between these modalities combined provides unique opportunities, including drug development and pharmacokinetic modeling. With the development of imaging systems that simultaneously acquire PET and fMRI signals, a need for analytical tools to interpret the recorded data has become paramount. My proposal focuses on the development of quantification schemes that use both signals.

I will investigate two areas where simultaneous PET-MR can make a significant difference: 1) assessment of drug effects by coupling drug binding to a receptor to its downstream effect in tissue, 2) using cerebral blood flow estimates to inform modeling of PET data. I will develop models that serve for quantification of simultaneous PET- and fMRI data, validate them via simulations, and evaluate them using experimental data.

The project will serve to leverage usage of simultaneous PET-MR, and assist in future studies with task- or drug-induced interventions. The project seeks to establish quantification methods that serve not only the imaging society, but specifically address the pharmaceutical companies' need to test their compounds prior to clinical trials.

By transitioning to hybrid imaging, I have the possibility to use my strong background in PET to impact a young field under development. The host institution is world leading in applied simultaneous PET-MR studies, thus the MSCA fellowship presents a unique possibility for me to gain invaluable knowledge of the next generation of medical imaging.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SIMPETMR" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SIMPETMR" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

Divided communities (2018)

Communities Under Siege: Everyday Challenges in the Divided City of Jerusalem

Read More  

COLOVOC (2019)

Reliable and specific urinary biomarkers for colorectal cancer

Read More  

TET2rec (2018)

Mechanisms of TET2 DNA demethylase recruitment to specific genomic regions

Read More