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TOBeATPAIN SIGNED

Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Total Cost €

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EC-Contrib. €

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Partnership

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 TOBeATPAIN project word cloud

Explore the words cloud of the TOBeATPAIN project. It provides you a very rough idea of what is the project "TOBeATPAIN" about.

glia    treatment    companies    aligned    union    interact    smes    cns    scientists    delivers    multidisciplinary    prevalence    network    molecules    perceive    entrepreneurially    valuable    neuroinflammation    damage    origin    technologies    scientific    complementary    central    knowledges    neurodegenerative    communication    releasing    platform    macrophages    profit    mechanism    business    young    musculoskeletal       astrocytes    cells    sectorial    microglia    innovative    quality    minded    suggest    whereby    altered    decreases    local    modulate    transferable    esrs    innovation    nervous    industrial    forging    transnational    perception    pain    life    pharmaceutical    gain    academic    causes    employability    neuropathies    performance    oriented    inflammatory    pathological    skills    tobeatpain    education    neuronal    neurones    itn    sectors    underlying    interdisciplinary    mechanisms    countries    creation    inter    beneficiaries    peripheral    charity    integrate    diseases    secondments    combines    signalling    career    eleven    sme    specialized    supervision    triangle    training    impair    encompassing    expertise    acquisition    pns   

Project "TOBeATPAIN" data sheet

The following table provides information about the project.

Coordinator
KING'S COLLEGE LONDON 

Organization address
address: STRAND
city: LONDON
postcode: WC2R 2LS
website: www.kcl.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 2˙870˙359 €
 EC max contribution 2˙870˙359 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2022-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KING'S COLLEGE LONDON UK (LONDON) coordinator 546˙575.00
2    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 527˙318.00
3    Universitätsklinikum Jena DE (Jena) participant 498˙432.00
4    Eli Lilly and Company Limited UK (Basingstoke) participant 273˙287.00
5    KANCERA AB SE (SOLNA) participant 263˙659.00
6    BIONORICA RESEARCH GMBH AT (INNSBRUCK) participant 255˙934.00
7    MEDIZINISCHE UNIVERSITAT INNSBRUCK AT (INNSBRUCK) participant 255˙934.00
8    UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT DE (WURZBURG) participant 249˙216.00

Map

 Project objective

Damage to the central (CNS) and peripheral (PNS) nervous systems causes altered perception of pain (pathological pain) which is a common feature of diseases that have high prevalence in the European Union. Both increases and decreases in the ability to perceive pain impair both performance at work and quality of life. Pathological pain in neurodegenerative diseases, musculoskeletal diseases and peripheral neuropathies is associated with neuroinflammation, the inflammatory process whereby non-neuronal (inflammatory and glia) cells interact with neurones by releasing molecules that modulate pain signalling. TOBeATPAIN suggest that neuroinflammation represents an underlying mechanism of pathological pain states encompassing those with a PNS or CNS origin. The focus of this ITN will be on the mechanisms by which non-neuronal cells impact on neuronal activity in order to identify innovative non-neuronal targets for the treatment of pathological pain in peripheral macrophages or CNS microglia/astrocytes. TOBeATPAIN delivers high-level scientific and innovation-oriented complementary training, forging career pathways to increase inter-sectorial and transnational employability of young entrepreneurially-minded scientists in the academic and industrial sectors. It combines the expertise of 5 leading academic institutions, 2 pharmaceutical companies and 1 SME as Beneficiaries, together with 2 SMEs and 1 non-profit research charity as Partner Organisations, from 4 European countries. Fully aligned with the ‘Knowledge Triangle’ (business, research, higher education) platform, eleven ESRs will gain valuable knowledge and multidisciplinary skills through interdisciplinary research projects that integrate state-of-the-art technologies, supervision by and secondments to industrial Network organisations, Network-wide and local training activities, and specialized transferable skills focused in the acquisition of the ‘3-Knowledges’ (K-creation, K-exploitation, K-communication).

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The information about "TOBEATPAIN" are provided by the European Opendata Portal: CORDIS opendata.

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