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Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Total Cost €


EC-Contrib. €






 TOBeATPAIN project word cloud

Explore the words cloud of the TOBeATPAIN project. It provides you a very rough idea of what is the project "TOBeATPAIN" about.

quality    causes    mechanisms    scientific    neuronal    diseases    academic    transnational    industrial    esrs    profit    performance    oriented    suggest    origin    eleven    charity    skills    itn    cns    releasing    tobeatpain    entrepreneurially    scientists    supervision    innovative    valuable    sme    specialized    signalling    beneficiaries    inflammatory    neuropathies    decreases    knowledges    platform    triangle    expertise    smes    molecules    companies    pharmaceutical    cells    complementary    pathological    mechanism    neurones    forging    glia    sectors    delivers    combines    multidisciplinary    microglia    creation    perception    pns    altered    modulate    interact    pain    secondments    technologies    acquisition    musculoskeletal    education    peripheral    interdisciplinary    neurodegenerative    damage    local    innovation    perceive    astrocytes    union    employability    central    life    business    integrate    young    macrophages    inter    underlying    treatment    transferable    nervous    training    countries    network    impair    aligned    career    whereby    prevalence    gain    encompassing    communication       minded    sectorial    neuroinflammation   

Project "TOBeATPAIN" data sheet

The following table provides information about the project.


Organization address
address: STRAND
city: LONDON
postcode: WC2R 2LS

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 2˙870˙359 €
 EC max contribution 2˙870˙359 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2022-07-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KING'S COLLEGE LONDON UK (LONDON) coordinator 546˙575.00
2    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 527˙318.00
3    Universitätsklinikum Jena DE (Jena) participant 498˙432.00
4    Eli Lilly and Company Limited UK (Basingstoke) participant 273˙287.00
5    KANCERA AB SE (SOLNA) participant 263˙659.00
6    BIONORICA RESEARCH GMBH AT (INNSBRUCK) participant 255˙934.00


 Project objective

Damage to the central (CNS) and peripheral (PNS) nervous systems causes altered perception of pain (pathological pain) which is a common feature of diseases that have high prevalence in the European Union. Both increases and decreases in the ability to perceive pain impair both performance at work and quality of life. Pathological pain in neurodegenerative diseases, musculoskeletal diseases and peripheral neuropathies is associated with neuroinflammation, the inflammatory process whereby non-neuronal (inflammatory and glia) cells interact with neurones by releasing molecules that modulate pain signalling. TOBeATPAIN suggest that neuroinflammation represents an underlying mechanism of pathological pain states encompassing those with a PNS or CNS origin. The focus of this ITN will be on the mechanisms by which non-neuronal cells impact on neuronal activity in order to identify innovative non-neuronal targets for the treatment of pathological pain in peripheral macrophages or CNS microglia/astrocytes. TOBeATPAIN delivers high-level scientific and innovation-oriented complementary training, forging career pathways to increase inter-sectorial and transnational employability of young entrepreneurially-minded scientists in the academic and industrial sectors. It combines the expertise of 5 leading academic institutions, 2 pharmaceutical companies and 1 SME as Beneficiaries, together with 2 SMEs and 1 non-profit research charity as Partner Organisations, from 4 European countries. Fully aligned with the ‘Knowledge Triangle’ (business, research, higher education) platform, eleven ESRs will gain valuable knowledge and multidisciplinary skills through interdisciplinary research projects that integrate state-of-the-art technologies, supervision by and secondments to industrial Network organisations, Network-wide and local training activities, and specialized transferable skills focused in the acquisition of the ‘3-Knowledges’ (K-creation, K-exploitation, K-communication).

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The information about "TOBEATPAIN" are provided by the European Opendata Portal: CORDIS opendata.

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