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TOBeATPAIN SIGNED

Targeting neuroinflammation to combat pathological pain in neurodegenerative diseases and chronic pain syndromes

Total Cost €

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EC-Contrib. €

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Partnership

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 TOBeATPAIN project word cloud

Explore the words cloud of the TOBeATPAIN project. It provides you a very rough idea of what is the project "TOBeATPAIN" about.

interdisciplinary    platform    creation    transferable    perception    microglia    academic    skills    complementary    inflammatory    signalling    employability    companies    education    releasing    pathological    causes    gain    entrepreneurially    network    scientists    nervous    pns    charity    technologies    eleven    astrocytes    valuable    neuroinflammation    musculoskeletal    modulate    oriented    cns    prevalence    specialized    transnational    inter    performance    sectors    perceive    integrate    treatment    supervision    diseases    life    mechanism    sectorial    tobeatpain    innovation       aligned    business    origin    altered    forging    neurodegenerative    damage    esrs    local    quality    union    beneficiaries    career    acquisition    neurones    secondments    profit    pain    underlying    young    sme    industrial    multidisciplinary    expertise    combines    triangle    central    glia    itn    mechanisms    suggest    training    macrophages    encompassing    peripheral    neuronal    minded    neuropathies    decreases    impair    communication    scientific    smes    whereby    countries    molecules    interact    knowledges    pharmaceutical    cells    innovative    delivers   

Project "TOBeATPAIN" data sheet

The following table provides information about the project.

Coordinator
KING'S COLLEGE LONDON 

Organization address
address: STRAND
city: LONDON
postcode: WC2R 2LS
website: www.kcl.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 2˙870˙359 €
 EC max contribution 2˙870˙359 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2022-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KING'S COLLEGE LONDON UK (LONDON) coordinator 546˙575.00
2    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 527˙318.00
3    Universitätsklinikum Jena DE (Jena) participant 498˙432.00
4    Eli Lilly and Company Limited UK (Basingstoke) participant 273˙287.00
5    KANCERA AB SE (SOLNA) participant 263˙659.00
6    BIONORICA RESEARCH GMBH AT (INNSBRUCK) participant 255˙934.00
7    MEDIZINISCHE UNIVERSITAT INNSBRUCK AT (INNSBRUCK) participant 255˙934.00
8    UNIVERSITAETSKLINIKUM WUERZBURG - KLINIKUM DER BAYERISCHEN JULIUS-MAXIMILIANS-UNIVERSITAT DE (WURZBURG) participant 249˙216.00

Map

 Project objective

Damage to the central (CNS) and peripheral (PNS) nervous systems causes altered perception of pain (pathological pain) which is a common feature of diseases that have high prevalence in the European Union. Both increases and decreases in the ability to perceive pain impair both performance at work and quality of life. Pathological pain in neurodegenerative diseases, musculoskeletal diseases and peripheral neuropathies is associated with neuroinflammation, the inflammatory process whereby non-neuronal (inflammatory and glia) cells interact with neurones by releasing molecules that modulate pain signalling. TOBeATPAIN suggest that neuroinflammation represents an underlying mechanism of pathological pain states encompassing those with a PNS or CNS origin. The focus of this ITN will be on the mechanisms by which non-neuronal cells impact on neuronal activity in order to identify innovative non-neuronal targets for the treatment of pathological pain in peripheral macrophages or CNS microglia/astrocytes. TOBeATPAIN delivers high-level scientific and innovation-oriented complementary training, forging career pathways to increase inter-sectorial and transnational employability of young entrepreneurially-minded scientists in the academic and industrial sectors. It combines the expertise of 5 leading academic institutions, 2 pharmaceutical companies and 1 SME as Beneficiaries, together with 2 SMEs and 1 non-profit research charity as Partner Organisations, from 4 European countries. Fully aligned with the ‘Knowledge Triangle’ (business, research, higher education) platform, eleven ESRs will gain valuable knowledge and multidisciplinary skills through interdisciplinary research projects that integrate state-of-the-art technologies, supervision by and secondments to industrial Network organisations, Network-wide and local training activities, and specialized transferable skills focused in the acquisition of the ‘3-Knowledges’ (K-creation, K-exploitation, K-communication).

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The information about "TOBEATPAIN" are provided by the European Opendata Portal: CORDIS opendata.

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