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EASYFISH SIGNED

Development of a new biomolecule to better control reproduction in fish

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 EASYFISH project word cloud

Explore the words cloud of the EASYFISH project. It provides you a very rough idea of what is the project "EASYFISH" about.

males    repropharm    mammals    induces    fish    steroidogenic    therapies    fishing    conventional    solution    34    injected    spontaneously    reproduction    rat    oocyte    species    soon    tool    salmon    bass    circulating    lh    exogenous    fsh    contrast    added    ovine    market    eggs    potentiate    sea    hormone    free    fragment    efficacy    porcine    source    binding    potentiating    female    special    consumption    class    treatment    environment    females    reproductive    hormonal    spontaneous    endogenous    monoclonal    world    treatments    efficiency    polyovulating    acts    captivity    injection    rate    freshwater    induce    issue    rp001    egg       bream    stimulate    farmed    carp    innovative    fertilized    disrupting    bovine    reliably    rp01    vet    maturation    trout    efficient    natural    nevertheless    supplies    hatchery    marine    consumers    operations    ie    manipulations    male    antibody    hormones    first    sustainable    spermatogenesis    farming    spermiation    ovulation    occursin   

Project "EASYFISH" data sheet

The following table provides information about the project.

Coordinator
REPROPHARM VET 

Organization address
address: CENTRE INRA VAL DE LOIRE SITE DE TOURS
city: NOUZILLY
postcode: 37380
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website http://www.repropharmvet.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2019-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    REPROPHARM VET FR (NOUZILLY) coordinator 50˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

'Fish farming is growing at 8% a year and will soon be the main source of fish for consumers. It supplies more than 34% of the world's fish consumption. Nevertheless, due to captivity environment some species have reproduction problems with no spontaneous ovulation in females and no spermiation in males. In some farmed freshwater species (ie, Carp, Salmon, Trout) and marine species (ie, Sea bass, Sea bream) the growth phase of reproductive development occursin captivity in contrast to oocyte maturation and ovulation in females, and spermiation in males that do not occur spontaneously. This problem requires exogenous hormonal therapies which are the only way to produce fertilized eggs reliably. In other species, these hormonal manipulations are used only as a management tool to enhance the efficiency of egg production, increase spermiation and facilitate hatchery operations. ReproPharm Vet developed a first in class monoclonal antibody RP01 and its fragment RP001, that are able to potentiate the activity of endogenous FSH and LH in mammals such as rat, bovine, ovine, porcine species. RP001 fragment can induce ovulation in female and stimulate spermatogenesis in male without any exogenous hormone injection. When injected, it acts directly on circulating FSH and LH hormones by binding to them and potentiating their activity. RP001 is more effective than conventional hormonal treatments it induces a better ovulation rate in polyovulating species and a better steroidogenic response in every species. Treatment with potentiating RP001 would be a highly innovative solution, hormone free, which could be a disrupting product in fishing market if we demonstrate its efficacy on fish FSH and LH. Its added value would be a more efficient method to induce ovulation and spermatogenesis without any exogenous hormone injection. RP001 would be a 'must-have' product to better control fish reproduction in a natural and sustainable way that represents a special issue on environment. '

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The information about "EASYFISH" are provided by the European Opendata Portal: CORDIS opendata.

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