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PET-AlphaSy SIGNED

PET Imaging of Alpha-Synuclein Fibril Formation

Total Cost €

0

EC-Contrib. €

0

Partnership

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 PET-AlphaSy project word cloud

Explore the words cloud of the PET-AlphaSy project. It provides you a very rough idea of what is the project "PET-AlphaSy" about.

reduce    diagnose    frontline    market    ineffective    visualization    ways    tracers    individual    healthcare    pharmaceutical    until    radioisotope    academic    pathogenic    probes    critical    personalized    medicinal    parkinson    presently    time    pet    expensive    spanning    biology    entrepreneurial    stage    gmp    respect    industry    assembled    effectiveness    limiting    insufficient    successful    chemistry    patient    fashion    diagnosis    treatments    skills    favorable    apparent    tomography    error    tailoring    trial    physicians    start    interdisciplinary    aid    unmet    tracer    training    too    treatment    drug    fibril    rely    protein    emission    generation    scientific    techniques    enterprises    modifying    nuclear    validated    pathology    pd    thought    pharmacy    alpha    rate    stages    train    leads    synuclein    strategy    molecular    diseases    aggregates    imaging    positron    goals    disease    scientists    hallmark    situation    medicine    radiopharmaceutical   

Project "PET-AlphaSy" data sheet

The following table provides information about the project.

Coordinator
KOBENHAVNS UNIVERSITET 

Organization address
address: NORREGADE 10
city: KOBENHAVN
postcode: 1165
website: www.ku.dk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Total cost 4˙100˙370 €
 EC max contribution 4˙100˙370 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2022-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 892˙566.00
2    STICHTING VUMC NL (AMSTERDAM) participant 796˙859.00
3    EBERHARD KARLS UNIVERSITAET TUEBINGEN DE (TUEBINGEN) participant 758˙365.00
4    UPPSALA UNIVERSITET SE (UPPSALA) participant 563˙965.00
5    REGION HOVEDSTADEN DK (HILLEROD) participant 297˙522.00
6    BIOARCTIC AB SE (STOCKHOLM) participant 281˙982.00
7    ELYSIA BE (LIEGE) participant 256˙320.00
8    JOHANNES GUTENBERG-UNIVERSITAT MAINZ DE (MAINZ) participant 252˙788.00
9    Eckert & Ziegler Eurotope GmbH DE (Berlin) partner 0.00
10    H. LUNDBECK AS DK (VALBY) partner 0.00
11    ION BEAM APPLICATIONS SA BE (OTTIGNIES LOUVAIN LA NEUVE) partner 0.00
12    NOVO NORDISK A/S DK (BAGSVAERD) partner 0.00
13    PMOD TECHNOLOGIES GMBH CH (ADLISWIL) partner 0.00
14    POSITRONPHARMA SA CL (SANTIAGO) partner 0.00
15    TAGWORKS PHARMACEUTICALS BV NL (Eindhoven) partner 0.00
16    UNIVERSITE DE LIEGE BE (LIEGE) partner 0.00

Map

 Project objective

Too often, physicians have to rely on a trial and error strategy until the most effective treatment for an individual patient is identified. This leads to a critical loss of time, making the healthcare system ineffective and expensive. In respect to drug development, a high failure rate is apparent at all stages of development and ways to reduce this have high priority for the pharmaceutical industry. To this end, drug development and medicinal treatment need to be more personalized and molecular imaging techniques, in particular Positron Emission Tomography (PET) imaging, can be used to achieve this by 1) evaluating the effectiveness of new treatments emerging from the pharmaceutical industry, 2) improving the ability to diagnose diseases, and 3) aid tailoring the treatment based on individual patient pathology. A limiting factor to develop new effective PET imaging probes is the insufficient number of radiopharmaceutical scientists presently available. Our consortium has assembled 6 radiopharmaceutical frontline academic and 10 non-academic partners to address this problem and train the next generation of radiopharmaceutical scientists. Our training will be focused on an unmet scientific need for Parkinson’s Disease (PD). Fibril formation of protein α-synuclein is thought to be the hallmark for PD, but presently, there are no validated PET tracers available for visualization of pathogenic aggregates of this protein. Our scientific goal is to develop such tracer. A successful tracer will have a strong impact on PD-diagnosis and facilitate the development of effective disease modifying treatments. To reach our goals, it is necessary to train our early stage researchers in a highly interdisciplinary fashion spanning from chemistry, over biology, GMP and pharmacy to nuclear medicine. Furthermore, this consortium will train entrepreneurial skills and facilitate start up new enterprises in the current favorable radioisotope market situation.

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The information about "PET-ALPHASY" are provided by the European Opendata Portal: CORDIS opendata.

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