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PET-AlphaSy SIGNED

PET Imaging of Alpha-Synuclein Fibril Formation

Total Cost €

EC-Contrib. €

Partnership

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PET-AlphaSy project word cloud

Explore the words cloud of the PET-AlphaSy project. It provides you a very rough idea of what is the project "PET-AlphaSy" about.

reduce diagnose frontline market ineffective visualization ways tracers individual healthcare pharmaceutical until radioisotope academic pathogenic probes critical personalized medicinal parkinson presently time pet expensive spanning biology entrepreneurial stage gmp respect industry assembled effectiveness limiting insufficient successful chemistry patient fashion diagnosis treatments skills favorable apparent tomography error tailoring trial physicians start interdisciplinary aid unmet tracer training too treatment drug fibril rely protein emission generation scientific techniques enterprises modifying nuclear validated pathology pd thought pharmacy alpha rate stages train leads synuclein strategy molecular diseases aggregates imaging positron goals disease scientists hallmark situation medicine radiopharmaceutical

Project "PET-AlphaSy" data sheet

The following table provides information about the project.

Coordinator	KOBENHAVNS UNIVERSITET Organization address address: NORREGADE 10 city: KOBENHAVN postcode: 1165 website: www.ku.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Denmark [DK]
Total cost	4˙100˙370 €
EC max contribution	4˙100˙370 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2018
Funding Scheme	MSCA-ITN-ETN
Starting year	2018
Duration (year-month-day)	from 2018-09-01 to 2022-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	KOBENHAVNS UNIVERSITET KOBENHAVNS UNIVERSITET Organization address address: NORREGADE 10 city: KOBENHAVN postcode: 1165 website: www.ku.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (KOBENHAVN)	coordinator	892˙566.00
2	STICHTING VUMC STICHTING VUMC Organization address address: DE BOELELAAN 1117 city: AMSTERDAM postcode: 1081 HV website: www.vumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	796˙859.00
3	EBERHARD KARLS UNIVERSITAET TUEBINGEN EBERHARD KARLS UNIVERSITAET TUEBINGEN Organization address address: GESCHWISTER-SCHOLL-PLATZ city: TUEBINGEN postcode: 72074 website: www.uni-tuebingen.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (TUEBINGEN)	participant	758˙365.00
4	UPPSALA UNIVERSITET UPPSALA UNIVERSITET Organization address address: VON KRAEMERS ALLE 4 city: UPPSALA postcode: 751 05 website: www.uu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (UPPSALA)	participant	563˙965.00
5	REGION HOVEDSTADEN REGION HOVEDSTADEN Organization address address: KONGENS VAENGE 2 city: HILLEROD postcode: 3400 website: www.regionh.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (HILLEROD)	participant	297˙522.00
6	BIOARCTIC AB BIOARCTIC AB Organization address address: WARFVINGES VAG 35 city: STOCKHOLM postcode: 112 51 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	281˙982.00
7	ELYSIA ELYSIA Organization address address: RUE DU SART-TILMAN 375 city: LIEGE postcode: 4031 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LIEGE)	participant	256˙320.00
8	JOHANNES GUTENBERG-UNIVERSITAT MAINZ JOHANNES GUTENBERG-UNIVERSITAT MAINZ Organization address address: SAARSTRASSE 21 city: MAINZ postcode: 55122 website: www.uni-mainz.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MAINZ)	participant	252˙788.00
9	Eckert & Ziegler Eurotope GmbH Eckert & Ziegler Eurotope GmbH Organization address address: Robert-Rössle-Str. 10 city: Berlin postcode: 13125 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Berlin)	partner	0.00
10	H. LUNDBECK AS H. LUNDBECK AS Organization address address: OTTILIAVEJ 7-9 city: VALBY postcode: 2500 website: www.lundbeck.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (VALBY)	partner	0.00
11	ION BEAM APPLICATIONS SA ION BEAM APPLICATIONS SA Organization address address: CHEMIN DU CYCLOTRON 3 city: OTTIGNIES LOUVAIN LA NEUVE postcode: 1348 website: www.iba-group.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (OTTIGNIES LOUVAIN LA NEUVE)	partner	0.00
12	NOVO NORDISK A/S NOVO NORDISK A/S Organization address address: NOVO ALLE 1 city: BAGSVAERD postcode: 2880 website: www.novonordisk.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (BAGSVAERD)	partner	0.00
13	PMOD TECHNOLOGIES GMBH PMOD TECHNOLOGIES GMBH Organization address address: RUTISTRASSE 20A city: ADLISWIL postcode: 8134 website: www.pmod.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ADLISWIL)	partner	0.00
14	POSITRONPHARMA SA POSITRONPHARMA SA Organization address address: RANCAGUA 878 city: SANTIAGO postcode: 7500921 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CL (SANTIAGO)	partner	0.00
15	TAGWORKS PHARMACEUTICALS BV TAGWORKS PHARMACEUTICALS BV Organization address address: Vondellaan 11 city: Eindhoven postcode: 5611 NX website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (Eindhoven)	partner	0.00
16	UNIVERSITE DE LIEGE UNIVERSITE DE LIEGE Organization address address: PLACE DU 20 AOUT 7 city: LIEGE postcode: 4000 website: www.ulg.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LIEGE)	partner	0.00

Map

Project objective

Too often, physicians have to rely on a trial and error strategy until the most effective treatment for an individual patient is identified. This leads to a critical loss of time, making the healthcare system ineffective and expensive. In respect to drug development, a high failure rate is apparent at all stages of development and ways to reduce this have high priority for the pharmaceutical industry. To this end, drug development and medicinal treatment need to be more personalized and molecular imaging techniques, in particular Positron Emission Tomography (PET) imaging, can be used to achieve this by 1) evaluating the effectiveness of new treatments emerging from the pharmaceutical industry, 2) improving the ability to diagnose diseases, and 3) aid tailoring the treatment based on individual patient pathology. A limiting factor to develop new effective PET imaging probes is the insufficient number of radiopharmaceutical scientists presently available. Our consortium has assembled 6 radiopharmaceutical frontline academic and 10 non-academic partners to address this problem and train the next generation of radiopharmaceutical scientists. Our training will be focused on an unmet scientific need for Parkinson’s Disease (PD). Fibril formation of protein α-synuclein is thought to be the hallmark for PD, but presently, there are no validated PET tracers available for visualization of pathogenic aggregates of this protein. Our scientific goal is to develop such tracer. A successful tracer will have a strong impact on PD-diagnosis and facilitate the development of effective disease modifying treatments. To reach our goals, it is necessary to train our early stage researchers in a highly interdisciplinary fashion spanning from chemistry, over biology, GMP and pharmacy to nuclear medicine. Furthermore, this consortium will train entrepreneurial skills and facilitate start up new enterprises in the current favorable radioisotope market situation.

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