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Opendata, web and dolomites

KlotoDx

KlotoDx A quick and cost-effective near-patient tool to identify sepsis-related bacteria and antibiotic resistances

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

KlotoDx project word cloud

Explore the words cloud of the KlotoDx project. It provides you a very rough idea of what is the project "KlotoDx" about.

preliminary house mostly antimicrobial worldwide primary algorithms disruptive antibiotics hours diagnosis detected segment validate intelligence place identification edge envision device klotodx broad manner boosts efficiency detection ribosomal total people adapt detect diagnosed blood bacterial apl opportunity solution market resistances causing investment 6m agents near acute engineering patient culture lethal disease takes feasibility instrument bacteria efficient appropriately moirai platform commercialize expressed characterization generation diagnostics first techniques enter sme artificial once care rates healthcare spectrum death caused 70 biodesign 24 30 day plan validated aand diagnostic resistance perform antibiotic treatment promyelocytic limited cutting time fast reduce rna leukemia sepsis genes dramatically patients

Project "KlotoDx" data sheet

The following table provides information about the project.

Coordinator	MOIRAI BIODESIGN S.L. Organization address address: GRAN VIA CORTS CATALANES, 272, 8 4 city: BARCELONA postcode: 8004 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.moiraibiodesign.com/index.html
Total cost	71˙429 €
EC max contribution	50˙000 € (70%)
Programme	1. H2020-EU.3. (PRIORITY 'Societal challenges) 2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs) 3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
Code Call	H2020-SMEInst-2018-2020-1
Funding Scheme	SME-1
Starting year	2018
Duration (year-month-day)	from 2018-09-01 to 2018-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	MOIRAI BIODESIGN S.L. MOIRAI BIODESIGN S.L. Organization address address: GRAN VIA CORTS CATALANES, 272, 8 4 city: BARCELONA postcode: 8004 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	coordinator	50˙000.00

Map

Project objective

Sepsis is a common disease caused mostly by bacteria that affects about 30 M people each year worldwide. If not diagnosed on time and treated appropriately, it may be lethal in 30% of cases and the cost for the healthcare system if not detected within the first 24 hours can rise dramatically. Current diagnostic techniques used to detect bacteria in patients’ blood, and identify their antimicrobial resistances, are still based on blood culture which takes more than 1 day and has a very limited detection efficiency. Moirai Biodesign is currently engineering a whole new generation of RNA-based diagnostics using both our in-house and cutting-edge artificial intelligence algorithms to detect ribosomal RNA from bacterial agents and expressed bacterial genes associated to common antibiotic resistances and a patient’s blood sample. Our platform is a near-patient, fast, efficient and cost-effective solution for the early detection and characterization of sepsis-related bacteria which will improve patient’s treatment, avoid broad-spectrum antibiotics’ side-effects and dramatically reduce death rates. Our technology has been preliminary validated for the diagnosis of Acute Promyelocytic Leukemia (APL) and KlotoDx’s main goal is to further adapt, validate and commercialize our disruptive diagnosis device for the identification of sepsis-causing bacteria and their antibiotic resistance genes. To achieve it and place our disruptive near-patient solution in the healthcare market, we envision a total investment of around €2.3 M and we plan to reach the 70% (around €1.6M) by applying for a Phase 2 within the H2020 SME-Instrument programme, once we perform the feasibility study during Phase 1. The increasing need for early sepsis diagnosis aand its characterization in terms of antibiotic resistance boosts KlotoDx’s opportunity to enter the primary care segment in a very disruptive manner.

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The information about "KLOTODX" are provided by the European Opendata Portal: CORDIS opendata.

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