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KlotoDx

KlotoDx A quick and cost-effective near-patient tool to identify sepsis-related bacteria and antibiotic resistances

Total Cost €

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EC-Contrib. €

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Partnership

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 KlotoDx project word cloud

Explore the words cloud of the KlotoDx project. It provides you a very rough idea of what is the project "KlotoDx" about.

generation    techniques    disruptive    lethal    bacteria    promyelocytic    device    aand    broad    care    identification    intelligence    sepsis    apl    investment    appropriately    validate    total    genes    plan    dramatically    validated    platform    takes    primary    resistance    detection    antibiotics    solution    klotodx    envision    death    spectrum    market    segment    expressed    once    day    place    people    disease    near    artificial    edge    leukemia    diagnosis    instrument    house    enter    reduce    manner    bacterial    efficient    biodesign    6m    first    perform    engineering    24    hours    limited    cutting    commercialize    30    sme    algorithms    preliminary    diagnosed    causing    diagnostics    diagnostic    detected    feasibility    healthcare    opportunity    acute    boosts    treatment    70    detect    patient    moirai    rna    antibiotic    time    fast    rates    resistances    mostly    culture    adapt    blood    antimicrobial    patients    caused    efficiency    agents    worldwide    ribosomal    characterization   

Project "KlotoDx" data sheet

The following table provides information about the project.

Coordinator
MOIRAI BIODESIGN S.L. 

Organization address
address: GRAN VIA CORTS CATALANES, 272, 8 4
city: BARCELONA
postcode: 8004
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://www.moiraibiodesign.com/index.html
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-09-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MOIRAI BIODESIGN S.L. ES (BARCELONA) coordinator 50˙000.00

Map

 Project objective

Sepsis is a common disease caused mostly by bacteria that affects about 30 M people each year worldwide. If not diagnosed on time and treated appropriately, it may be lethal in 30% of cases and the cost for the healthcare system if not detected within the first 24 hours can rise dramatically. Current diagnostic techniques used to detect bacteria in patients’ blood, and identify their antimicrobial resistances, are still based on blood culture which takes more than 1 day and has a very limited detection efficiency. Moirai Biodesign is currently engineering a whole new generation of RNA-based diagnostics using both our in-house and cutting-edge artificial intelligence algorithms to detect ribosomal RNA from bacterial agents and expressed bacterial genes associated to common antibiotic resistances and a patient’s blood sample. Our platform is a near-patient, fast, efficient and cost-effective solution for the early detection and characterization of sepsis-related bacteria which will improve patient’s treatment, avoid broad-spectrum antibiotics’ side-effects and dramatically reduce death rates. Our technology has been preliminary validated for the diagnosis of Acute Promyelocytic Leukemia (APL) and KlotoDx’s main goal is to further adapt, validate and commercialize our disruptive diagnosis device for the identification of sepsis-causing bacteria and their antibiotic resistance genes. To achieve it and place our disruptive near-patient solution in the healthcare market, we envision a total investment of around €2.3 M and we plan to reach the 70% (around €1.6M) by applying for a Phase 2 within the H2020 SME-Instrument programme, once we perform the feasibility study during Phase 1. The increasing need for early sepsis diagnosis aand its characterization in terms of antibiotic resistance boosts KlotoDx’s opportunity to enter the primary care segment in a very disruptive manner.

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The information about "KLOTODX" are provided by the European Opendata Portal: CORDIS opendata.

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