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PEP-NET SIGNED

Predictive Epigenetics: Fusing Theory and Experiment

Total Cost €

0

EC-Contrib. €

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Partnership

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Project "PEP-NET" data sheet

The following table provides information about the project.

Coordinator
HUMBOLDT-UNIVERSITAET ZU BERLIN 

Organization address
address: UNTER DEN LINDEN 6
city: BERLIN
postcode: 10117
website: www.hu-berlin.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 4˙062˙699 €
 EC max contribution 4˙062˙699 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-11-01   to  2022-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HUMBOLDT-UNIVERSITAET ZU BERLIN DE (BERLIN) coordinator 758˙365.00
2    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD UK (OXFORD) participant 606˙345.00
3    DIAGENODE BE (SERAING) participant 512˙640.00
4    JOHN INNES CENTRE UK (NORWICH) participant 303˙172.00
5    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) participant 297˙522.00
6    FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION CH (BASEL) participant 281˙276.00
7    CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE FR (ILLKIRCH GRAFFENSTADEN) participant 274˙802.00
8    OSPEDALE SAN RAFFAELE SRL IT (MILANO) participant 261˙499.00
9    UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II IT (NAPOLI) participant 261˙499.00
10    MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC) DE (BERLIN) participant 252˙788.00
11    MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV DE (MUENCHEN) participant 252˙788.00
12    Oxford Biodynamics Limited UK (Oxford) partner 0.00
13    Oxford Nanoimaging Ltd UK (Oxford) partner 0.00
14    THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CORP US (PHILADELPHIA) partner 0.00
15    THE UNIVERSITY OF ADELAIDE AU (ADELAIDE) partner 0.00
16    UNIVERSITY OF EAST ANGLIA UK (NORWICH) partner 0.00

Map

 Project objective

Epigenetic mechanisms of gene regulation are profoundly implicated in human health and disease. However, we are still far from a complete mechanistic understanding of many epigenetic processes. Without an understanding of mechanisms we cannot fully understand function in healthy cells, in disease states, and the effects and side effects of therapeutic interventions. This severely limits the development of healthcare strategies. Research in epigenetics has typically been based on experiments and not on theory. Although this has delivered large amounts of information, information alone is not sufficient. Further progress urgently needs a paradigm shift in the way in which we study epigenetics, namely: epigenetics needs mathematics. Mathematical models are essential to capture and understand the complex, dynamic and stochastic nature of epigenetic regulation. Models are immensely powerful because they identify unifying concepts and enable predictions of system properties. Modelling epigenetic processes not only holds the key to a deep mechanistic understanding, but also ultimately, to drug response predictions, patient-specific diagnoses and new therapies. One of the greatest challenges to uniting biology and mathematics is the barrier between disciplines, because education in each field has traditionally been mono-disciplinary. The PEP-NET ITN will overcome these barriers by uniting 16 outstanding European academic laboratories and companies who have pioneered the successful combination of theoretical and experimental epigenetics. PEP-NET will train a new cohort of 15 European researchers to combine quantitative experiments with predictive theoretical models, and to apply this knowledge to basic and applied questions of epigenetic function.

 Deliverables

List of deliverables.
Network logo designed Other 2019-10-15 13:12:24
Network website online Websites, patent fillings, videos etc. 2019-10-15 13:12:40
Network information flyer complete Other 2019-10-15 13:12:36

Take a look to the deliverables list in detail:  detailed list of PEP-NET deliverables.

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The information about "PEP-NET" are provided by the European Opendata Portal: CORDIS opendata.

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