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MagnoBeads

Removing endotoxins during sepsis: a blood purification platform using magnetic nanoparticles

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 MagnoBeads project word cloud

Explore the words cloud of the MagnoBeads project. It provides you a very rough idea of what is the project "MagnoBeads" about.

eth    trials    founded    uniquely    care    19    purification    spin    excellent    commercialization    units    feasibility    curative    usability    models    intensive    hemotune    septic    ip    authorization    strategies    2017    removing    sized    clinical    composition    freedom    commercial    prototype    ready    rate    financially    device    financial    nanoparticles    successfully    z    billion    subsequently    huge    move    delivering    wyss    off    proprietary    zurich    million    patient    removes    put    capture    capitalize    gebert    endotoxins    treatments    foundation    filtered    people    selectively    designed    employs    academic    filter    engineering    solid    molecules    strategy    combined    responsible    sepsis    swiss    treatment    uuml    exists    treat    smei    platform    relieving    mortality    operate    market    receive    human    position    upscaling    nanoparticle    evaluation    death    2026    small    tested    ongoing    company    opportunity    blood    symptoms    halted    animal    magnetic    entails    30    stabilizing    regulatory    cure    commercialize    dialysis   

Project "MagnoBeads" data sheet

The following table provides information about the project.

Coordinator		 HEMOTUNE AG 

Organization address
address: C/O ETH ZURICH WEINBERGSTRASSE 35 WEH F14
city: ZURICH
postcode: 8092
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Switzerland [CH]
 Project website http://www.hemotune.ch
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-12-01   to  2019-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HEMOTUNE AG CH (ZURICH) coordinator 50˙000.00

Map

 Project objective

Hemotune is a Swiss academic spin-off company founded in 2017 to commercialize proprietary blood purification technology using uniquely designed magnetic nanoparticles, developed at ETH Zürich. Hemotune is financially supported by Wyss Zurich and the Gebert Rüf foundation to develop a product to treat sepsis. Sepsis affects 19 million people each year, and with a mortality rate of 30% it is the most common cause of death in intensive care units. Currently, no cure for sepsis exists, and treatment focuses on relieving symptoms. Therefore, a huge market opportunity exists for curative sepsis treatments, which is estimated to reach €4.3 billion by 2026.

Using its proprietary blood purification technology, hemotune aims to capitalize on this market opportunity by developing a dialysis-like device that removes endotoxins (molecules responsible for sepsis) from the blood. This device employs magnetic nanoparticles to selectively capture endotoxins, which are subsequently filtered out of the blood by a magnetic filter. By removing these endotoxins, the septic response is halted, stabilizing the patient. This technology was successfully tested in small-scale animal models, and now R&D activities will focus on developing a human-sized prototype product, ready for clinical evaluation.

Financial support from the SMEi phase 1 will be used to assess the technical and commercial feasibility of the nanoparticle-based blood purification platform as a treatment strategy for sepsis. Technical feasibility includes usability engineering, and feasibility studies into the upscaling, and into regulatory feasibility to receive market authorization. Commercial feasibility entails a freedom to operate analysis, and composition of solid IP and commercialization strategies. This SMEi phase 1 feasibility study, combined with the ongoing R&D delivering the prototype product, put hemotune in an excellent position to rapidly move forward towards clinical trials.

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The information about "MAGNOBEADS" are provided by the European Opendata Portal: CORDIS opendata.

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