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MagnoBeads

Removing endotoxins during sepsis: a blood purification platform using magnetic nanoparticles

Total Cost €

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EC-Contrib. €

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Partnership

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 MagnoBeads project word cloud

Explore the words cloud of the MagnoBeads project. It provides you a very rough idea of what is the project "MagnoBeads" about.

move    removes    human    2026    responsible    swiss    put    halted    cure    ready    gebert    rate    mortality    removing    clinical    market    magnetic    operate    capture    care    successfully    death    hemotune    intensive    evaluation    company    foundation       million    upscaling    off    commercialization    treatment    solid    blood    treatments    animal    commercialize    models    endotoxins    authorization    commercial    prototype    combined    academic    purification    sepsis    composition    treat    molecules    relieving    uuml    selectively    people    founded    uniquely    patient    designed    tested    employs    filtered    strategy    subsequently    19    spin    units    receive    filter    trials    smei    nanoparticles    platform    usability    ip    opportunity    curative    regulatory    zurich    eth    excellent    financial    symptoms    proprietary    capitalize    device    entails    ongoing    nanoparticle    strategies    wyss    sized    freedom    septic    small    position    feasibility    stabilizing    exists    delivering    30    2017    huge    financially    dialysis    billion    engineering   

Project "MagnoBeads" data sheet

The following table provides information about the project.

Coordinator
HEMOTUNE AG 

Organization address
address: C/O ETH ZURICH WEINBERGSTRASSE 35 WEH F14
city: ZURICH
postcode: 8092
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Project website http://www.hemotune.ch
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-12-01   to  2019-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HEMOTUNE AG CH (ZURICH) coordinator 50˙000.00

Map

 Project objective

Hemotune is a Swiss academic spin-off company founded in 2017 to commercialize proprietary blood purification technology using uniquely designed magnetic nanoparticles, developed at ETH Zürich. Hemotune is financially supported by Wyss Zurich and the Gebert Rüf foundation to develop a product to treat sepsis. Sepsis affects 19 million people each year, and with a mortality rate of 30% it is the most common cause of death in intensive care units. Currently, no cure for sepsis exists, and treatment focuses on relieving symptoms. Therefore, a huge market opportunity exists for curative sepsis treatments, which is estimated to reach €4.3 billion by 2026.

Using its proprietary blood purification technology, hemotune aims to capitalize on this market opportunity by developing a dialysis-like device that removes endotoxins (molecules responsible for sepsis) from the blood. This device employs magnetic nanoparticles to selectively capture endotoxins, which are subsequently filtered out of the blood by a magnetic filter. By removing these endotoxins, the septic response is halted, stabilizing the patient. This technology was successfully tested in small-scale animal models, and now R&D activities will focus on developing a human-sized prototype product, ready for clinical evaluation.

Financial support from the SMEi phase 1 will be used to assess the technical and commercial feasibility of the nanoparticle-based blood purification platform as a treatment strategy for sepsis. Technical feasibility includes usability engineering, and feasibility studies into the upscaling, and into regulatory feasibility to receive market authorization. Commercial feasibility entails a freedom to operate analysis, and composition of solid IP and commercialization strategies. This SMEi phase 1 feasibility study, combined with the ongoing R&D delivering the prototype product, put hemotune in an excellent position to rapidly move forward towards clinical trials.

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The information about "MAGNOBEADS" are provided by the European Opendata Portal: CORDIS opendata.

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