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synBIOcarb SIGNED

Synthetic biology of carbohydrate-binding proteins: engineering protein-carbohydrate interactions for diagnostics and cell targeting

Total Cost €

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EC-Contrib. €

0

Partnership

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Project "synBIOcarb" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITY OF LEEDS 

Organization address
address: WOODHOUSE LANE
city: LEEDS
postcode: LS2 9JT
website: www.leeds.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 4˙093˙660 €
 EC max contribution 4˙093˙660 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2018
 Funding Scheme MSCA-ITN-ETN
 Starting year 2018
 Duration (year-month-day) from 2018-10-01   to  2022-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITY OF LEEDS UK (LEEDS) coordinator 909˙517.00
2    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) participant 595˙044.00
3    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) participant 549˙604.00
4    ACIB GMBH AT (GRAZ) participant 528˙414.00
5    ALBERT-LUDWIGS-UNIVERSITAET FREIBURG DE (FREIBURG) participant 505˙576.00
6    CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED SK (BRATISLAVA) participant 466˙493.00
7    GLYCODIAG FR (CHEVILLY) participant 274˙802.00
8    ENGENES BIOTECH GMBH AT (WIEN) participant 264˙207.00
9    Elicityl SA FR (Crolles) partner 0.00
10    GLYCOSELECT LTD IE (DUBLIN) partner 0.00
11    KAROLINSKA INSTITUTET SE (STOCKHOLM) partner 0.00
12    TECHNISCHE UNIVERSITAET GRAZ AT (GRAZ) partner 0.00
13    UNIVERSITAET FUER BODENKULTUR WIEN AT (WIEN) partner 0.00
14    UNIVERSITE D'ORLEANS FR (ORLEANS CEDEX 2) partner 0.00

Map

 Project objective

The aim of the Initial Training Network will be to train 15 early stage researchers in the emerging field of synthetic glycobiology, equipping them with the skills needed for future careers in the medical technologies sector. Every living cell is covered in a coating of complex carbohydrates known as the glycocalyx. Anything that approaches the cell membrane must first descend through this forest of carbohydrates. Interactions between carbohydrates and lectins (carbohydrate-binding proteins) play essential roles in cell adhesion and endocytosis. Our growing understanding of glycoscience, and the advent of chemical and synthetic biology methodologies, presents an opportunity to redesign, synthesise and exploit glycocalyx and lectin components for diverse analytical, diagnostic and targeted therapeutic applications: this is the field of Synthetic Glycobiology. The ESF-funded report, “A Roadmap for Glycosicence in Europe”, has highlighted the importance of glycoscience to the European bioeconomy. The European glycomics market is growing rapidly (>10% growth p.a.). There is an urgent need to train ESRs with the scientific and entrepreneurial skills required to enable European industry to exploit this rapidly growing market. The synBIOcarb ETN brings together a diverse team of chemists, structural biologists, biophysicists, cell biologists and protein engineers who are pioneering the development of Synthetic Glycobiology, and four SMEs that are leading industrial innovation in glycoscience and protein engineering. Together, we will train 15 ESRs in the essential enabling technologies that underpin the development and exploitation of glycoscience: glycoconjugate synthesis; lectin engineering; biophysical interaction measurements; cell biology; analytical device technologies; entrepreneurial and transferable skills.

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The information about "SYNBIOCARB" are provided by the European Opendata Portal: CORDIS opendata.

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