Explore the words cloud of the GAtransport project. It provides you a very rough idea of what is the project "GAtransport" about.
The following table provides information about the project.
TEL AVIV UNIVERSITY
|Coordinator Country||Israel [IL]|
|Total cost||1˙500˙000 €|
|EC max contribution||1˙500˙000 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2016-02-01 to 2021-01-31|
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|1||TEL AVIV UNIVERSITY||IL (TEL AVIV)||coordinator||1˙500˙000.00|
Plants evolved a unique molecular mechanism that spatially regulate auxin, forming finely tuned gradients and local maxima of auxin that inform and direct developmental patterning and adaptive growth processes. Recent findings call into question the uniqueness of polar auxin transport in the sense that more plant hormones seem to be actively transported. Although still lacking many mechanistic details, as well as comprehensive functional connotations, these findings warrant a more thorough investigation into the prospect of a broader scope for plants spatial regulation capacity in the context of additional hormones. Critically, we lack an effective set of tools to directly investigate and dissect the particulars of plant hormones mobility at the molecular level. My long-term goal is to provide a molecular and mechanistic understanding of plant hormones dynamics that will augment our evolving model of how they are regulated and how they convey information. Here, I hypothesize that GA mobility in plants is controlled and directed by an active transport mechanism to form distinct distribution patterns that affect signaling. I will test my hypothesis with a multi-faceted and multi-disciplinary approach, combining: fluorescent labeling of key gibberellins to map their accumulation sites in whole plants and at the sub-cellular level; chemical-biology strategies that facilitate manipulation of GA “origin point” in planta to map and quantify GA flow pathways; probe-based genetic screens and un-biased photo-affinity labeling to identify proteins affecting GA mobility; and genetic and molecular biology techniques to characterize identified proteins’ functions. I expect to offer an exceptional, detailed view into the inner workings of gibberellins dynamics in planta and into the mechanisms driving it. I further anticipate that the strategies developed here to specifically address gibberellins could be straightforwardly re-tailored to investigate additional plant hormones.
|year||authors and title||journal||last update|
Dnyaneshwar Kand, Lorena Pizarro, Inbar Angel, Adi Avni, Dinorah Friedmann-Morvinski, Roy Weinstain
Organelle-Targeted BODIPY Photocages: Visible-Light-Mediated Subcellular Photorelease
published pages: 4659-4663, ISSN: 1433-7851, DOI: 10.1002/anie.201900850
|Angewandte Chemie International Edition 58/14||2019-04-16|
TomÃ¡Å¡ Slanina, Pradeep Shrestha, Eduardo Palao, Dnyaneshwar Kand, Julie A. Peterson, Andrew S. Dutton, Naama Rubinstein, Roy Weinstain, Arthur H. Winter, Petr KlÃ¡n
In Search of the Perfect Photocage: Structureâ€“Reactivity Relationships in meso -Methyl BODIPY Photoremovable Protecting Groups
published pages: 15168-15175, ISSN: 0002-7863, DOI: 10.1021/jacs.7b08532
|Journal of the American Chemical Society 139/42||2019-04-18|
Shira Wexler, Hilla Schayek, Kandhikonda Rajendar, Iris Tal, Eilon Shani, Yasmine Meroz, Roman Dobrovetsky, Roy Weinstain
Characterizing gibberellin flow in planta using photocaged gibberellins
published pages: 1500-1505, ISSN: 2041-6520, DOI: 10.1039/c8sc04528c
|Chemical Science 10/5||2019-04-16|
Jenia Binenbaum, Roy Weinstain, Eilon Shani
Gibberellin Localization and Transport in Plants
published pages: 410-421, ISSN: 1360-1385, DOI: 10.1016/j.tplants.2018.02.005
|Trends in Plant Science 23/5||2019-04-04|
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