Opendata, web and dolomites

GAtransport SIGNED

A direct, multi-faceted approach to investigate plant hormones spatial regulation: the case of gibberellins

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 GAtransport project word cloud

Explore the words cloud of the GAtransport project. It provides you a very rough idea of what is the project "GAtransport" about.

biased    ga    dynamics    maxima    scope    molecular    uniqueness    transport    transported    hormones    tuned    signaling    patterns    augment    screens    fluorescent    functions    strategies    local    polar    adaptive    mechanistic    sense    driving    spatial    lack    view    mechanisms    anticipate    sub    hypothesize    developmental    mechanism    probe    cellular    form    photo    labeling    critically    details    prospect    dissect    workings    capacity    regulation    functional    connotations    auxin    active    patterning    quantify    direct    tools    planta    combining    point    warrant    particulars    manipulation    directed    plants    thorough    genetic    faceted    actively    proteins    un    disciplinary    accumulation    origin    regulate    seem    re    question    sites    convey    lacking    map    biology    gradients    chemical    regulated    context    techniques    forming    inner    gibberellins    model    flow    affinity    plant    exceptional    straightforwardly    mobility    investigation    hypothesis    additional    finely    inform   

Project "GAtransport" data sheet

The following table provides information about the project.

Coordinator
TEL AVIV UNIVERSITY 

Organization address
address: RAMAT AVIV
city: TEL AVIV
postcode: 69978
website: http://www.tau.ac.il/

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Israel [IL]
 Project website http://www.weinstainlab.com
 Total cost 1˙500˙000 €
 EC max contribution 1˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-STG
 Funding Scheme ERC-STG
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2021-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TEL AVIV UNIVERSITY IL (TEL AVIV) coordinator 1˙500˙000.00

Map

 Project objective

Plants evolved a unique molecular mechanism that spatially regulate auxin, forming finely tuned gradients and local maxima of auxin that inform and direct developmental patterning and adaptive growth processes. Recent findings call into question the uniqueness of polar auxin transport in the sense that more plant hormones seem to be actively transported. Although still lacking many mechanistic details, as well as comprehensive functional connotations, these findings warrant a more thorough investigation into the prospect of a broader scope for plants spatial regulation capacity in the context of additional hormones. Critically, we lack an effective set of tools to directly investigate and dissect the particulars of plant hormones mobility at the molecular level. My long-term goal is to provide a molecular and mechanistic understanding of plant hormones dynamics that will augment our evolving model of how they are regulated and how they convey information. Here, I hypothesize that GA mobility in plants is controlled and directed by an active transport mechanism to form distinct distribution patterns that affect signaling. I will test my hypothesis with a multi-faceted and multi-disciplinary approach, combining: fluorescent labeling of key gibberellins to map their accumulation sites in whole plants and at the sub-cellular level; chemical-biology strategies that facilitate manipulation of GA “origin point” in planta to map and quantify GA flow pathways; probe-based genetic screens and un-biased photo-affinity labeling to identify proteins affecting GA mobility; and genetic and molecular biology techniques to characterize identified proteins’ functions. I expect to offer an exceptional, detailed view into the inner workings of gibberellins dynamics in planta and into the mechanisms driving it. I further anticipate that the strategies developed here to specifically address gibberellins could be straightforwardly re-tailored to investigate additional plant hormones.

 Publications

year authors and title journal last update
List of publications.
2019 Dnyaneshwar Kand, Lorena Pizarro, Inbar Angel, Adi Avni, Dinorah Friedmann-Morvinski, Roy Weinstain
Organelle-Targeted BODIPY Photocages: Visible-Light-Mediated Subcellular Photorelease
published pages: 4659-4663, ISSN: 1433-7851, DOI: 10.1002/anie.201900850
Angewandte Chemie International Edition 58/14 2019-04-16
2017 Tomáš Slanina, Pradeep Shrestha, Eduardo Palao, Dnyaneshwar Kand, Julie A. Peterson, Andrew S. Dutton, Naama Rubinstein, Roy Weinstain, Arthur H. Winter, Petr Klán
In Search of the Perfect Photocage: Structure–Reactivity Relationships in meso -Methyl BODIPY Photoremovable Protecting Groups
published pages: 15168-15175, ISSN: 0002-7863, DOI: 10.1021/jacs.7b08532
Journal of the American Chemical Society 139/42 2019-04-18
2019 Shira Wexler, Hilla Schayek, Kandhikonda Rajendar, Iris Tal, Eilon Shani, Yasmine Meroz, Roman Dobrovetsky, Roy Weinstain
Characterizing gibberellin flow in planta using photocaged gibberellins
published pages: 1500-1505, ISSN: 2041-6520, DOI: 10.1039/c8sc04528c
Chemical Science 10/5 2019-04-16
2018 Jenia Binenbaum, Roy Weinstain, Eilon Shani
Gibberellin Localization and Transport in Plants
published pages: 410-421, ISSN: 1360-1385, DOI: 10.1016/j.tplants.2018.02.005
Trends in Plant Science 23/5 2019-04-04

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "GATRANSPORT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "GATRANSPORT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

PROGRESS (2019)

The Enemy of the Good: Towards a Theory of Moral Progress

Read More  

DISINTEGRATION (2019)

The Mass Politics of Disintegration

Read More  

VictPart (2019)

Righting Victim Participation in Transitional Justice

Read More