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ChemPrime SIGNED

A new crop protection strategy by chemical priming of the plant immune system

Total Cost €


EC-Contrib. €






 ChemPrime project word cloud

Explore the words cloud of the ChemPrime project. It provides you a very rough idea of what is the project "ChemPrime" about.

environment    homoserine    proportion    buswell    crops    effectiveness    discoveries    losses    pesticide    biol    residues    adoption    multiple    health    plants    companies    2018    annually    diseases    waste    translational    commercial    perceive    capacity    attractive    chemprime    plant    rbh    nature    co    enhanced    former    structural    protection    acid    immune    impacts    pest    stakeholders    primes    genetic    inducing    economically    disease    streams    yield    2014    phytol    commercially    examine    undesirable    luna    pesticides    erc    crop    attackers    optimise    collaborative    reduce    priming    economic    resistance    tech    baba    chemicals    mechanisms    first    beta    never    defences    et    benefits    agents    resist    initiate    stress    defensive    aminobutyric    insights    uncoupled    engagement    showed    reached    proof    strategy    discovered    full    formulation    prime    revealed    al    chemical    chem    lost    global    agri   

Project "ChemPrime" data sheet

The following table provides information about the project.


Organization address
postcode: S10 2TN

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 148˙318 €
 EC max contribution 148˙318 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2020-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF SHEFFIELD UK (SHEFFIELD) coordinator 148˙318.00


 Project objective

A large proportion of global crop yield is annually lost to plant diseases. While pesticides help to reduce these losses, there are growing concerns about pesticide resistance and their impacts on health and environment. The objective of this proof-of-concept project is to develop a crop protection technology that is based on priming of the plant’s own immune system, providing an enhanced defensive capacity to resist attackers. While priming is considered attractive for exploitation in integrated pest and disease management, chemical priming agents have never reached their full economic potential due to undesirable non-target effects on plant growth and yield. My former ERC project (‘Prime-A-Plant ́) has revealed key insights in the mechanisms by which plants perceive and respond to priming-inducing chemicals. We showed that the benefits of priming by beta-aminobutyric acid (BABA) can be uncoupled from the associated stress response (Luna et al. 2014; Nature Chem. Biol.). More recently, we discovered a structural analogue of BABA, R-beta-homoserine (RBH), which primes plant defences against multiple diseases without affecting growth (Buswell et al. 2018; New Phytol.). The current ‘ChemPrime’ project aims to develop these discoveries into a crop protection strategy through co-design with commercial stakeholders. The first project part involves translational research to make the concept more attractive for adoption by commercial stakeholders. We will examine the effectiveness of RBH against a range of economically relevant crop diseases, identify genetic targets in crops to improve the effectiveness of the RBH priming response, assess chemical residues in crop products and waste streams, and optimise RBH formulation for applications in different production systems. The second project part involves engagement activities to initiate collaborative research & development with agri-tech companies and develop the concept into a commercially viable crop protection strategy.

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The information about "CHEMPRIME" are provided by the European Opendata Portal: CORDIS opendata.

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