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ChemPrime SIGNED

A new crop protection strategy by chemical priming of the plant immune system

Total Cost €


EC-Contrib. €






 ChemPrime project word cloud

Explore the words cloud of the ChemPrime project. It provides you a very rough idea of what is the project "ChemPrime" about.

disease    et    resist    chem    co    lost    mechanisms    chemicals    streams    erc    priming    discoveries    plants    nature    effectiveness    structural    capacity    stress    tech    yield    prime    buswell    homoserine    diseases    pesticides    adoption    biol    genetic    pest    engagement    initiate    pesticide    commercially    proof    economically    uncoupled    environment    agents    strategy    chemprime    examine    optimise    commercial    waste    attackers    rbh    al    acid    never    beta    crop    reached    defences    multiple    attractive    aminobutyric    plant    undesirable    impacts    residues    defensive    economic    baba    full    luna    annually    agri    translational    losses    2018    insights    stakeholders    inducing    chemical    discovered    first    health    formulation    benefits    protection    primes    collaborative    showed    global    crops    immune    2014    enhanced    reduce    phytol    revealed    proportion    former    companies    perceive    resistance   

Project "ChemPrime" data sheet

The following table provides information about the project.


Organization address
postcode: S10 2TN

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 148˙318 €
 EC max contribution 148˙318 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2020-10-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF SHEFFIELD UK (SHEFFIELD) coordinator 148˙318.00


 Project objective

A large proportion of global crop yield is annually lost to plant diseases. While pesticides help to reduce these losses, there are growing concerns about pesticide resistance and their impacts on health and environment. The objective of this proof-of-concept project is to develop a crop protection technology that is based on priming of the plant’s own immune system, providing an enhanced defensive capacity to resist attackers. While priming is considered attractive for exploitation in integrated pest and disease management, chemical priming agents have never reached their full economic potential due to undesirable non-target effects on plant growth and yield. My former ERC project (‘Prime-A-Plant ́) has revealed key insights in the mechanisms by which plants perceive and respond to priming-inducing chemicals. We showed that the benefits of priming by beta-aminobutyric acid (BABA) can be uncoupled from the associated stress response (Luna et al. 2014; Nature Chem. Biol.). More recently, we discovered a structural analogue of BABA, R-beta-homoserine (RBH), which primes plant defences against multiple diseases without affecting growth (Buswell et al. 2018; New Phytol.). The current ‘ChemPrime’ project aims to develop these discoveries into a crop protection strategy through co-design with commercial stakeholders. The first project part involves translational research to make the concept more attractive for adoption by commercial stakeholders. We will examine the effectiveness of RBH against a range of economically relevant crop diseases, identify genetic targets in crops to improve the effectiveness of the RBH priming response, assess chemical residues in crop products and waste streams, and optimise RBH formulation for applications in different production systems. The second project part involves engagement activities to initiate collaborative research & development with agri-tech companies and develop the concept into a commercially viable crop protection strategy.

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The information about "CHEMPRIME" are provided by the European Opendata Portal: CORDIS opendata.

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