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ChemPrime SIGNED

A new crop protection strategy by chemical priming of the plant immune system

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ChemPrime project word cloud

Explore the words cloud of the ChemPrime project. It provides you a very rough idea of what is the project "ChemPrime" about.

engagement    beta    co    former    residues    defensive    mechanisms    aminobutyric    full    homoserine    strategy    2014    genetic    disease    health    prime    et    impacts    initiate    examine    plant    primes    tech    luna    inducing    baba    effectiveness    2018    economic    economically    biol    buswell    chem    plants    waste    resist    crop    optimise    stress    attractive    pesticides    agents    resistance    rbh    translational    uncoupled    never    immune    formulation    defences    revealed    protection    acid    perceive    losses    commercial    al    reduce    benefits    companies    chemicals    discovered    collaborative    lost    annually    streams    structural    agri    phytol    pest    adoption    insights    diseases    stakeholders    priming    attackers    discoveries    enhanced    proportion    environment    capacity    pesticide    showed    commercially    multiple    first    yield    proof    erc    crops    chemical    chemprime    global    undesirable    reached    nature   

Project "ChemPrime" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF SHEFFIELD 

Organization address
address: FIRTH COURT WESTERN BANK
city: SHEFFIELD
postcode: S10 2TN
website: www.shef.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
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 Coordinator Country United Kingdom [UK]
 Total cost 148˙318 €
 EC max contribution 148˙318 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2020-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF SHEFFIELD UK (SHEFFIELD) coordinator 148˙318.00

Map

 Project objective

A large proportion of global crop yield is annually lost to plant diseases. While pesticides help to reduce these losses, there are growing concerns about pesticide resistance and their impacts on health and environment. The objective of this proof-of-concept project is to develop a crop protection technology that is based on priming of the plant’s own immune system, providing an enhanced defensive capacity to resist attackers. While priming is considered attractive for exploitation in integrated pest and disease management, chemical priming agents have never reached their full economic potential due to undesirable non-target effects on plant growth and yield. My former ERC project (‘Prime-A-Plant ́) has revealed key insights in the mechanisms by which plants perceive and respond to priming-inducing chemicals. We showed that the benefits of priming by beta-aminobutyric acid (BABA) can be uncoupled from the associated stress response (Luna et al. 2014; Nature Chem. Biol.). More recently, we discovered a structural analogue of BABA, R-beta-homoserine (RBH), which primes plant defences against multiple diseases without affecting growth (Buswell et al. 2018; New Phytol.). The current ‘ChemPrime’ project aims to develop these discoveries into a crop protection strategy through co-design with commercial stakeholders. The first project part involves translational research to make the concept more attractive for adoption by commercial stakeholders. We will examine the effectiveness of RBH against a range of economically relevant crop diseases, identify genetic targets in crops to improve the effectiveness of the RBH priming response, assess chemical residues in crop products and waste streams, and optimise RBH formulation for applications in different production systems. The second project part involves engagement activities to initiate collaborative research & development with agri-tech companies and develop the concept into a commercially viable crop protection strategy.

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