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ReSurface SIGNED

A combined developmental cell biology and tissue engineering approach to repair the articular surface of synovial joints

Total Cost €

EC-Contrib. €

Partnership

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ReSurface project word cloud

Explore the words cloud of the ReSurface project. It provides you a very rough idea of what is the project "ReSurface" about.

school hsci developmental skills hms engineering university medical bch collaborations transferable training invasive repair fundamental minimally hospital harvard therapy industry populations bsl defect creates maintenance panel combining galway scientific centre intersectoral children strategies uchg affiliated platform medicine boston defects site techniques cartilage return phd international brigham craft mechanisms biology women cells gaps biomaterials transition nuig lab multidisciplinary fellowship duffy scientist adulthood ram diversify prof professional articular generation independent resurface national unravelling remedi limited clinical suitable consensus collaborators regenerative lack molecular april foundation ideal cell stem source competencies garry uacute college me science safe ireland outgoing dr

Project "ReSurface" data sheet

The following table provides information about the project.

Coordinator	NATIONAL UNIVERSITY OF IRELAND GALWAY Organization address address: UNIVERSITY ROAD city: Galway postcode: H91 website: www.nuigalway.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Total cost	248˙063 €
EC max contribution	248˙063 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2017
Funding Scheme	MSCA-IF-GF
Starting year	2019
Duration (year-month-day)	from 2019-08-01 to 2022-07-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	NATIONAL UNIVERSITY OF IRELAND GALWAY NATIONAL UNIVERSITY OF IRELAND GALWAY Organization address address: UNIVERSITY ROAD city: Galway postcode: H91 website: www.nuigalway.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Galway)	coordinator	248˙063.00
2	CHILDREN'S HOSPITAL CORPORATION CHILDREN'S HOSPITAL CORPORATION Organization address address: LONGWOOD AVENUE 300 city: BOSTON postcode: 2115 website: http://www.childrenshospital.org/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (BOSTON)	partner	0.00

Map

Project objective

Repair of articular cartilage defects remains a significant clinical challenge due to gaps in our knowledge of articular cartilage development and maintenance in adulthood. This creates a lack of consensus on the ideal cell source for cell-based repair strategies and suitable methods of delivery. The overall goal of ReSurface is to develop a cell therapy platform for articular cartilage defect repair. This will be achieved by unravelling the molecular mechanisms controlling articular cartilage cell development and maintenance, generation of a panel of molecular parameters defining populations of cells that are safe and suitable for articular cartilage repair, and development of a minimally invasive method to deliver cells to the defect site. This project is highly multidisciplinary and intersectoral combining fundamental developmental and molecular cell biology with advanced engineering techniques and including significant industry and clinical collaboration throughout. This fellowship will have an outgoing phase at Dr April Craft’s Lab at Boston Children’s Hospital (BCH), affiliated with Harvard Medical School (HMS) and the Harvard Stem Cell Institute (HSCI), and a return phase to Prof Garry Duffy’s Lab at the National University of Ireland, Galway (NUIG) which is part of the Science Foundation Ireland funded Centre for Research in Medical Devices (CÚRAM). Clinical collaborators will include BCH, Brigham and Women’s Hospital, Boston, University College Hospital Galway (UCHG) and the Regenerative Medicine Institute (REMEDI) at NUIG while industry collaborators include Boston Scientific Limited (BSL). Having recently completed my PhD in biomaterials development, this project will diversify my professional competencies through advanced training with intersectoral and international collaborations and provide me with the scientific and transferable skills required for my transition to an independent scientist role.

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The information about "RESURFACE" are provided by the European Opendata Portal: CORDIS opendata.