Opendata, web and dolomites

BRIGHTER SIGNED

BIOPRINTING BY LIGHT-SHEET LITHOGRAPHY: ENGINEERING COMPLEX TISSUES WITH HIGH RESOLUTION AT HIGH SPEED

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 BRIGHTER project word cloud

Explore the words cloud of the BRIGHTER project. It provides you a very rough idea of what is the project "BRIGHTER" about.

dimensional    vivo    layer    3d    vascular    microfeatures    incorporate    illumination    sheet    tissues    decrease    insufficient    original    printing    hollow    limited    laden    follicles    geometries    morphologies    skin    wavy    nature    fails    hydrogels    material    spatial    evaginations    voxels    stiffness    anatomical    sweat    impacting    crosslinking    confined    fine    requiring    integrity    density    appendix    remarkable    selectively    academy    digital    superior    light    tuned    matrix    photomasks    brighter    engineered    create    recreate    device    alternative    times    disruptive    pharma    vitro    additional    fabrication    scientific    speed    contrast    niches    native    invaginations    severely    ultimate    mechanical    viability    cell    surrogates    business    combine    resolution    maintaining    proof    heterogeneous    photocrosslink    compartments    hair    lithography    structures    poor    clinical    sacrificial    network    glands    sectors    tissue    cellular    stem    bioprinting   

Project "BRIGHTER" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA 

Organization address
address: CARRER BALDIRI REIXAC PLANTA 2A 10-12
city: BARCELONA
postcode: 8028
website: http://www.ibecbarcelona.eu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 3˙520˙720 €
 EC max contribution 3˙459˙052 € (98%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-2018-2019-2020-01
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2022-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA ES (BARCELONA) coordinator 750˙106.00
2    MYCRONIC AB SE (TABY) participant 945˙960.00
3    JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN DE (FRANKFURT AM MAIN) participant 704˙346.00
4    TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY IL (HAIFA) participant 588˙015.00
5    CELLENDES GMBH DE (REUTLINGEN) participant 470˙625.00

Map

 Project objective

Engineered tissues are key elements in both in vitro and in vivo applications, strongly impacting the academy, pharma and clinical sectors. Bioprinting is considered the most promising method to produce such engineered tissues. However, current bioprinting methods are severely limited by both insufficient speed and spatial resolution. Long printing times decrease cell viability, while poor spatial resolution fails to recreate the heterogeneous nature of native tissues. BRIGHTER will develop a new bioprinting technology able to produce tissue surrogates with high spatial resolution at high printing speed using an original top-down lithography approach, in contrast with current bottom-up, layer-by-layer bioprinting methods. BRIGHTER will combine high-speed light-sheet illumination and high-resolution digital photomasks to selectively photocrosslink cell-laden hydrogels in confined voxels and produce three-dimensional complex geometries. This process will enable the bioprinting of key anatomical microfeatures of tissue such as invaginations, evaginations or wavy morphologies. It will also incorporate hollow vascular structures while maintaining tissue mechanical integrity without the need of additional sacrificial material. As a remarkable feature, matrix crosslinking density can be fine-tuned using BRIGHTER’s approach, allowing the fabrication of cellular compartments requiring specific matrix stiffness such as stem cell niches. The proof-of-concept application will be bioprinting viable engineered skin tissues exploiting the key features of the BRIGHTER device: skin appendix (hair follicles, sweat glands), stem cell niches and a vascular network. The ultimate goal is to provide a superior alternative to state-or-the art 3D bioprinting with a disruptive bioprinting technology that would create new scientific and business opportunities.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "BRIGHTER" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "BRIGHTER" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.2.1.)

BRIEFING (2018)

Bridging the FET Innovation Gap

Read More  

RSENSE (2020)

Revolutionizing disease and environmental detection with portable optoacoustic sensing

Read More  

ATEMPGRAD (2019)

Analysing Temperature Effects with a Mobile and Precise Gradient Device

Read More