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One4Two SIGNED

All-in-one genetic test for fast and accurate diagnosis of the causes of infertility

Total Cost €

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EC-Contrib. €

0

Partnership

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 One4Two project word cloud

Explore the words cloud of the One4Two project. It provides you a very rough idea of what is the project "One4Two" about.

consolidating    infertility    couples    fragmented    business    25    infertile    handful    diagnosis    workload    cumbersome    suitable    simplify    complicates    software    model    lack    transmission    inherited    pricing    cover    reagents    couple    report    treat    tests    protocol    diagnostic    investigation    price    provides    scores    uncomprehensive    genetic    reproductive    prepare    first    ground    time    service    laboratories    proprietary    disorder    fertility    marketing    diseases    desire    preventing    gynecologist    poised    adding    batteries    million    citizens    gynecologists    parent    35    times    probability    caused    origin    days    generation    certifications    negatively    causes    psychological    dna    upscaling    blood    impacts    distress    linked    kronosdna    panel    sequencing    effectiveness    pregnancy    reduce    complete    strategy    affordable    fulfilling    lab    one4two    commercialization    therapies    optimized    mutations    prescribed   

Project "One4Two" data sheet

The following table provides information about the project.

Coordinator
KRONOSDNA S.R.L. 

Organization address
address: VIA LOGGIA DEI PISANI 25
city: NAPOLI
postcode: 80133
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website https://kronosdna.blog/
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-02-01   to  2019-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KRONOSDNA S.R.L. IT (NAPOLI) coordinator 50˙000.00

Map

 Project objective

Infertility is a disorder of the reproductive system which affects 25 million citizens in Europe, preventing them from fulfilling their desire to become a parent. To identify its causes, genetic testing is prescribed to around 35% of the couples under diagnosis, since several factors related to infertility have a genetic origin. However, the effectiveness of infertility genetic analysis and the whole diagnosis process are affected by several issues: an uncomprehensive approach to fertility genetic test, with just a handful of genetic diseases being investigated, each through a dedicated test; a fragmented and cumbersome genetic investigation process that negatively impacts on the couple, adding to the psychological distress caused by infertility, with several batteries of tests often in different laboratories, long diagnosis times and high costs; the lack of a specific genetic testing protocol and diagnosis report for infertility, which increases the workload for laboratories and complicates the diagnosis by gynecologists. KronosDNA has developed One4Two, the first integrated system that provides a comprehensive diagnostic service for the infertile couple, able to cover the whole diagnostic path from lab analysis (through a panel of reagents to analyse DNA through Next Generation Sequencing) to the diagnostic report (by means of a proprietary analysis software). One4Two, with just one blood sample, in 5 days and at an affordable price, provides a complete report on the mutations linked to infertility, probability scores for the transmission of inherited diseases, and the most suitable ART therapies to treat infertility. This is poised to reduce analysis workload, simplify diagnosis by the gynecologist and reduce time to pregnancy. During Phase 1 project, the system will be optimized with end-users to prepare the ground for the required certifications, upscaling and commercialization, by also consolidating the business model, the marketing strategy and the pricing.

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The information about "ONE4TWO" are provided by the European Opendata Portal: CORDIS opendata.

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