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Lakhesys SIGNED

Lakhesys: building the machine to make the medicines of tomorrow

Total Cost €

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EC-Contrib. €

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Partnership

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Project "Lakhesys" data sheet

The following table provides information about the project.

Coordinator
ASTRAVEUS SAS 

Organization address
address: 6 RUE JEAN CALVIN
city: PARIS
postcode: 75012
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 2˙817˙143 €
 EC max contribution 1˙972˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-2
 Funding Scheme SME-2
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2021-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ASTRAVEUS SAS FR (PARIS) coordinator 1˙972˙000.00

Map

 Project objective

Chimeric Antigen Receptor T-cell therapies (‘CAR-T’) are ushering in an incredibly exciting era of using a patient’s own cells to cure their cancer. The prospect of using a patient’s own cells to cure their disease is theoretically limitless. However, with all of this excitement comes a shadow. The cost of these life-saving treatments is currently so prohibitive that it threatens to put extreme cost-pressure on healthcare providers globally in the years ahead.

Astraveus has developed a highly innovative microfluidic chip that can fundamentally change the CAR-T industry. This chip answers the need to lower production cost (by ~70%), improve treatment quality and allow upscaling of treatment volumes to the required levels. Astraveus has also developed equipment to optimize the use of these microfluidic chips. They have incorporated these technologies into a working prototype of an instrument called ‘Lakhesys’. This instrument allows for automated, standalone, end-to-end production of a CAR-T therapy.

The design, fabrication and validation of the microfluidic innovation is a real breakthrough in the ability to cheaply and accurately produce these treatments. The further step of incorporating these chips into a prototype system demonstrates the huge potential for automating CAR-T production. This phase-2 project will upgrade the supporting modules to turn this working prototype into a launch-ready product. It will also support the validation and industrialisation steps to bring this innovation to market.

The industry is dominated by players in the USA and China (72% of CAR-T institutions are based in these two countries). Astraveus has invented something incredibly unique and a complete step-change versus anything seen on the market. As such, we present an opportunity to support the creation of a homegrown EU business that can challenge the status quo and, more importantly, put these life-saving therapies in the hands of all patients who need them.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "LAKHESYS" project.

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The information about "LAKHESYS" are provided by the European Opendata Portal: CORDIS opendata.

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