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GSYNCOR SIGNED

Graphene-syncronized coherent Raman scattering laser and microscope

Total Cost €

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EC-Contrib. €

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Partnership

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 GSYNCOR project word cloud

Explore the words cloud of the GSYNCOR project. It provides you a very rough idea of what is the project "GSYNCOR" about.

spontaneous    diagnostic    depending    tumour    bulky    prevented    clinical    label    followed    free    generating    consuming    vivo    dual    locked    generates    laser    pulses    molecules    quantitative    light    drastically    illuminated    tissue    inspection    speed    proven    imaging    ultrashort    scattering    raman    graphene    staining    weak    molecular    disruptive    orders    slow    discriminate    judgement    hurdle    measuring    sensitivity    broadband    mode    adoption    visual    subjective    technique    heavily    doctor    ultrafast    wavelength    reducing    pulsed    diseased    costly    nonlinear    informed    immediately    healthy    signal    coherent    gsyncor    standard    setting    microscopy    patient    superposition    specificity    reliability    operation    composition    complexity    therapeutic    optical    acquisition    colour    illuminating    ing    time    specialized    prohibiting    image    decisions    excisions    obtain    histopathology    hours    capability    magnitude    lasers    grade    synchronized    synchronize    crs    complete    diagnostics    handling    biomedical    passively    qualitative    doctors    drawback    invasive    simplify   

Project "GSYNCOR" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 149˙628 €
 EC max contribution 149˙628 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-PoC
 Funding Scheme ERC-POC
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2020-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 149˙628.00

Map

 Project objective

The current standard of tumour diagnostics is histopathology, where excisions are taken from the tissue of a diseased patient, followed by staining and visual inspection. The process is time-consuming, costly, with low sensitivity and specificity. The results are subjective and qualitative, heavily depending on the judgement of the doctor. Spontaneous Raman microscopy is a label-free and non-invasive imaging technique, which enables to obtain objective and quantitative information on the tissue, by measuring its detailed molecular composition. It has proven capability to discriminate between healthy and tumour tissue and to identify the type and grade of tumour. Its main drawback is the very weak Raman signal, resulting in slow acquisition speed. This means that acquisition of a complete image would take up to several hours, prohibiting real-time and in vivo imaging. Coherent Raman scattering (CRS) generates the signal from a coherent superposition of the molecules in the tissue, illuminated by two synchronized ultrashort light pulses of different colour, thus improving by several orders of magnitude the acquisition speed. This enables real-time, in vivo imaging of the tissue allowing doctors to make informed diagnostic and/or therapeutic decisions immediately. The main hurdle of CRS microscopy, which has prevented its widespread adoption in a clinical setting, is the complexity and the high cost of the illuminating laser system, which is bulky and requires handling by specialized personnel. GSYNCOR aims to drastically simplify the laser system used for CRS microscopy, increasing its reliability and reducing its cost by exploiting the ultrafast and broadband nonlinear optical response of graphene. This enables not only pulsed (mode-locked) operation of a laser system, but also to passively synchronize two different lasers, generating the dual-wavelength pulses required for CRS. This will enable the uptake of CRS as a disruptive biomedical imaging technology.

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The information about "GSYNCOR" are provided by the European Opendata Portal: CORDIS opendata.

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