Opendata, web and dolomites

AmygdalaNeuroMod SIGNED

Unraveling the combinatorial logic of amygdala neuromodulation in decision-making and learning.

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 AmygdalaNeuroMod project word cloud

Explore the words cloud of the AmygdalaNeuroMod project. It provides you a very rough idea of what is the project "AmygdalaNeuroMod" about.

foundations    mice    stimuli    manipulate    depends    threat    surprisingly    types    emotional    circuits    group    independent    interplay    depression    holds    little    mood    elucidating    physiological    career    opportunity    keys    balance    neuromodulator    network    behaving    functional    proper    circuitry    synaptic    record    neuromodulatory    treating    leader    core    serotonin    laboratory    circuit    logic    innervated    brain    plays    fundamentally    acetylcholine    neurotransmitters    modern    anxiety    almost    disorder    reward    neuronal    genetic    host    ranging    context    interactions    behavioral    me    learning    disorders    salience    region    fellowship    inputs    tools    neuromodulators    cell    regions    neuromodulation    released    regulates    guided    expand    imbalance    mental    alterations    sub    amygdala    neurotechnologies    critical    norepinephrine    basic    europeans    dopamine    combine    decision    expertise    simultaneously    electrophysiology    function   

Project "AmygdalaNeuroMod" data sheet

The following table provides information about the project.

Coordinator
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION 

Organization address
address: MAULBEERSTRASSE 66
city: BASEL
postcode: 4058
website: www.fmi.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 191˙149 €
 EC max contribution 191˙149 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-09-01   to  2022-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION CH (BASEL) coordinator 191˙149.00

Map

 Project objective

Proper neuronal circuit function depends fundamentally on the balance of neuromodulators, a set of neurotransmitters released widely throughout the brain. Almost every mental disorder, including anxiety and depression, that affect one out of four Europeans, are associated with a neuromodulatory imbalance in specific sub-circuits. Elucidating the role of different neuromodulatory inputs to specific brain regions holds the keys to understanding and treating mood disorders.

The amygdala plays an essential role in the processing of emotional stimuli and salience, ranging from reward to threat and synaptic alterations in this region are critical for learning and emotional processing. Amygdala is innervated by every major neuromodulator, yet surprisingly little is known about the activity of these inputs under physiological conditions and how neuromodulation regulates amygdala circuit activity during different behavioral states and learning.

Here, I propose to study the functional role of neuromodulatory inputs to the amygdala circuitry during learning and decision-making. Towards this goal, I will combine my experience in large-scale electrophysiology with the expertise of the host laboratory in modern genetic tools and neurotechnologies to simultaneously record and manipulate the activity of dopamine, serotonin, norepinephrine and acetylcholine inputs to the amygdala during context-guided decision-making in behaving mice. Using this approach, I aim to characterize the logic of interactions between neuromodulators and its implementation at the level of defined circuits and cell types in the amygdala and to demonstrate the role of this coordination in defining network activity, behavioral state and learning.

The fellowship will contribute to our basic understanding of the interplay between two core brain systems, while it will provide me with a unique opportunity to expand my expertise and establish the foundations of my future career as an independent group leader.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "AMYGDALANEUROMOD" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "AMYGDALANEUROMOD" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

PNAIC (2018)

Positive and Negative Asymmetry in Intergroup Contact: Its Impact on Linguistic Forms of Communication and Physiological Responses

Read More  

PI3K MODULATORS (2019)

Identification and characterisation of new class of PI3K modulators in oncology

Read More  

MarshFlux (2020)

The effect of future global climate and land-use change on greenhouse gas fluxes and microbial processes in salt marshes

Read More