Opendata, web and dolomites

Foldmetcat SIGNED

Bioinspired Catalytic Metallofoldamers

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 Foldmetcat project word cloud

Explore the words cloud of the Foldmetcat project. It provides you a very rough idea of what is the project "Foldmetcat" about.

close    cyclase    explore    rooted    paradigm    resorcinarene    intrinsic    digold    phosphonite    mimicking    folding    metallic    generate    ligands    types    attain    single    purpose    polyenes    gold    containing    inherent    cavitant    activate    diphosphines    enantioselectively    metal    structurally    prototypes    enzymes    transition    skeletons    sites    centers    reactive    clusters    series    donor    zinc    catalytic    inspired    catalysts    cyclization    carbenes    chiral    substrate    cascades    polyenynes    carbocation    heterocyclic    fundamental    metals    taxol    activation    substrates    chemistry    heterobimetallic    modes    larger    arrangement    site    mixed    supramolecular    prepare    polyunsaturated    bond    stereogenic    organometallic    delineate    reaction    unprecedented    carbocyclic    distant    hydrogen    translocation    ophiobolin    reactivity    complexes    electrophilic    c2    terpenoid    simultaneously    fold    initial    pairing    anion    unconventional    efficient    initiated    intramolecular    first    cyclizations   

Project "Foldmetcat" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA 

Organization address
address: AVENIDA PAISSOS CATALANS 16
city: TARRAGONA
postcode: 43007
website: www.iciq.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 2˙500˙000 €
 EC max contribution 2˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-ADG
 Funding Scheme ERC-ADG
 Starting year 2019
 Duration (year-month-day) from 2019-09-01   to  2024-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO PRIVADA INSTITUT CATALA D'INVESTIGACIO QUIMICA ES (TARRAGONA) coordinator 2˙500˙000.00

Map

 Project objective

Inspired by mimicking the characteristics of terpenoid cyclase enzymes, the goal of this proposal is to design new types of catalysts containing electrophilic transition metal centers that could simultaneously fold and activate polyunsaturated substrates promoting non-inherent cyclization modes. Our goal is unprecedented, although it is rooted on fundamental organometallic chemistry, in particular, on the known activation of polyunsaturated substrates by highly electrophilic transition metals. These unconventional cyclizations cascades challenge the paradigm that the intrinsic reactivity of the substrate is the relevant factor in carbocation-initiated processes and would provide access to large carbocyclic skeletons such as those present in taxol and ophiobolin enantioselectively in a single step under catalytic conditions. Although the initial work will be carried out with gold catalysts, a major goal of this research is to develop other general-purpose efficient chiral electrophilic catalysts based on zinc. To attain our goal, we will study more simple catalysts to delineate the factors that control the folding of polyenynes and polyenes. Thus, we will prepare new series of C2-chiral catalysts in which the stereogenic elements are close to the reaction site. Related C2-chiral systems will be generated by supramolecular hydrogen-bond pairing. A similar chiral arrangement could also be achieved by an intramolecular chiral anion translocation from the metal to a distant hydrogen-bond donor site. In addition, we will explore larger systems based on structurally well-defined metallic clusters to generate highly electrophilic chiral reactive sites. The folding and activation of polyunsaturated substrates will be studied first with a series of catalytic prototypes based on digold or heterobimetallic complexes with N-heterocyclic carbenes, diphosphines, mixed ligands of these types, as well as resorcinarene-phosphonite cavitant ligands.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "FOLDMETCAT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "FOLDMETCAT" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

DISINTEGRATION (2019)

The Mass Politics of Disintegration

Read More  

PROGRESS (2019)

The Enemy of the Good: Towards a Theory of Moral Progress

Read More  

HyperBio (2019)

Vis-NIR Hyperspectral imaging for biomaterial quality control

Read More