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ERMADA SIGNED

Illuminating Earth’s microbial diversity and origins from metagenomes with deep learning

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ERMADA project word cloud

Explore the words cloud of the ERMADA project. It provides you a very rough idea of what is the project "ERMADA" about.

machine    functions    unknown    footprint    trained    sequence    composition    nutrient    climate    microorganisms    roles    reference    structure    conventional    bioinformatics    shotgun    habitats    uncharacterized    hundreds    play    models    cutting    plants    represented    algorithms    planet    gain    biomass    taxonomically    environments    data    marine    metagenomic    genes    microbial    capture    biogeochemical    12    pertaining    sequences    record    terabytes    community    network    stars    cycles    sequencing       lineages    employ    outnumbers    effort    samples    latter    evolution    enzymes    analyze    patterns    learning    painstaking    microbes    emerged    govern    terrestrial    galaxy    biodiversity    staggering    animals    networks    volumes    serve    deep    whereas    exceeds    metabolic    microbiome       genome    milky    species    earth    classifying    complete    big    levels    classify    prevalent    environmental    circulation    origins    cultured    99    similarity    edge    regulating    capacities    deeper    rank    diversity    elucidate    neural    dataset    twofold    uncover    classified    10    abstract   

Project "ERMADA" data sheet

The following table provides information about the project.

Coordinator
BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING 

Organization address
address: FLEMING STREET 34
city: VARI-ATHENS
postcode: 16672
website: www.fleming.gr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Greece [EL]
 Total cost 247˙628 €
 EC max contribution 247˙628 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-CAR
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2023-03-09

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    BIOMEDICAL SCIENCES RESEARCH CENTER ALEXANDER FLEMING EL (VARI-ATHENS) coordinator 247˙628.00

Map

 Project objective

The estimated number of microbes on our planet outnumbers the stars of the Milky Way galaxy and their biomass exceeds that of all plants and animals. Out of the 10^12 microbial species, only around 10^4 have been cultured, less than 10^5 species are represented by classified sequences, and a staggering estimated 99% of these microorganisms remain taxonomically unknown. Metagenomic shotgun sequencing has emerged as the most prevalent way of studying and classifying microorganisms from various habitats whereas genome analysis can be used to uncover the functions of genes, enzymes and metabolic pathways in a microbial community. This painstaking effort is crucial to understanding Earth's biodiversity, as microbes play important roles in regulating the planet’s biogeochemical cycles through processes that govern nutrient circulation in both terrestrial and marine environments. In this proposal, we will employ cutting edge bioinformatics and machine learning algorithms to analyze and elucidate Earth’s microbial diversity. We will use deep neural networks trained by large volumes of metagenomic sequences as well as big data methods to process hundreds of terabytes of data and taxonomically classify all uncharacterized metagenomic samples, by identifying their origins and habitats. Going beyond the capacities of conventional sequence similarity and comparison analyses, neural network models can capture higher level, abstract defining features and patterns in metagenomic sequences. The aim of this study is twofold: i) to gain a deeper understanding of the composition and structure of the microbiome at different rank levels and lineages and ii) to provide a complete record of the planet’s present microbial diversity footprint. The latter can serve as a reference dataset for future studies pertaining to microbiome evolution due to climate change or other long-term environmental factors.

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The information about "ERMADA" are provided by the European Opendata Portal: CORDIS opendata.

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