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Cyanide Evolution SIGNED

EVOLUTION OF CYANIDE METABOLIMS IN APOSEMATIC BUTTERFLIES: from gene characterization to community ecology

Total Cost €

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EC-Contrib. €

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Partnership

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 Cyanide Evolution project word cloud

Explore the words cloud of the Cyanide Evolution project. It provides you a very rough idea of what is the project "Cyanide Evolution" about.

evolutionary    give    genetic    me    trajectory    programing    toxic    heliconius    chance    biology    vary    hotspot    editing    trained    compounds    communication    expertise    supervision    cas    forest    opportunity    excel    subtropical    valuable    metabolomics    community    progress    reaching    tropical    cyanide    communities    transcriptomics    populations    phenomics    position    of    releasing    butterflies    aposematims    tribe    biochemistry    varies    bioinformatics    skills    expand    teaching    bases    genetics    models    career    unravel    extremely    brazilian    endangered    toxicity    statistical    combine    contain    glucosides    unknown    basis    decipher    fellowship    evolution    cyanogenesis    defence    heliconiine    extreme    mimicry    multidisciplinary    biosynthesize    passiflora    expression    atlantic    interactions    academia    larval    techniques    ecology    omics    cyanogenic    colourful    gene    deforestation    repertoire    biodiversity    brings    co    shaped    plants    phenotipic    feeding    matabolomics    crispr   

Project "Cyanide Evolution" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 224˙933.00

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 Project objective

The colourful and toxic Heliconius butterflies are well-established models to study evolution of aposematims and mimicry, yet the genetic basis of their toxicity and how this varies in different populations remains unknown. Heliconius are toxic butterflies because they contain cyanide-releasing compounds called cyanogenic glucosides, which they can both biosynthesize or uptake from Passiflora plants, their co-evolutionary partner, during larval feeding. This multidisciplinary project brings together ecology, genetics, biochemistry and evolutionary biology to investigate how toxicity and interactions with Passiflora plants has shaped the evolution of these butterflies. Thus, I will combine the gene-editing technology CRISPR-Cas with different OMICs approaches (metabolomics, transcriptomics and phenomics) to (1) decipher the genetic and phenotipic bases of cyanogenesis in Heliconius butterflies and (2) unravel the evolutionary trajectory of this defence system in the Heliconiine tribe. Moreover, I will also (3) establish how cyanogenesis vary within and between tropical and subtropical heliconiine-Passiflora communities of the Brazilian Atlantic Forest, a biodiversity hotspot endangered by extreme deforestation. This project will give me the unique opportunity to expand my knowledge and skills repertoire on genetics, ecology, evolutionary biology and bioinformatics. I will be trained in advanced techniques such CRISPR-Cas, gene expression analysis, R programing, statistical methods applied to community ecology and matabolomics, etc. Also, during this fellowship I will excel my teaching/supervision, project management and communication abilities. All these expertise will be extremely valuable for the execution of the project and will bring great progress to my career development, increasing my chance of of reaching a long-term position in academia.

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The information about "CYANIDE EVOLUTION" are provided by the European Opendata Portal: CORDIS opendata.

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