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Cyanide Evolution SIGNED

EVOLUTION OF CYANIDE METABOLIMS IN APOSEMATIC BUTTERFLIES: from gene characterization to community ecology

Total Cost €

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EC-Contrib. €

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Partnership

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 Cyanide Evolution project word cloud

Explore the words cloud of the Cyanide Evolution project. It provides you a very rough idea of what is the project "Cyanide Evolution" about.

gene    basis    populations    crispr    phenomics    community    excel    plants    multidisciplinary    co    academia    of    biochemistry    give    extreme    biology    statistical    decipher    bioinformatics    shaped    expertise    genetics    techniques    career    extremely    tropical    contain    trained    interactions    passiflora    programing    toxicity    atlantic    omics    teaching    tribe    valuable    trajectory    cyanide    me    metabolomics    matabolomics    evolutionary    subtropical    opportunity    toxic    editing    biodiversity    reaching    communities    unknown    releasing    vary    combine    chance    defence    cyanogenesis    hotspot    heliconius    communication    progress    genetic    cyanogenic    evolution    forest    feeding    varies    bases    position    brazilian    glucosides    colourful    transcriptomics    brings    unravel    skills    heliconiine    phenotipic    supervision    expression    ecology    expand    models    compounds    biosynthesize    repertoire    deforestation    butterflies    cas    endangered    fellowship    larval    aposematims    mimicry   

Project "Cyanide Evolution" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 224˙933.00

Map

 Project objective

The colourful and toxic Heliconius butterflies are well-established models to study evolution of aposematims and mimicry, yet the genetic basis of their toxicity and how this varies in different populations remains unknown. Heliconius are toxic butterflies because they contain cyanide-releasing compounds called cyanogenic glucosides, which they can both biosynthesize or uptake from Passiflora plants, their co-evolutionary partner, during larval feeding. This multidisciplinary project brings together ecology, genetics, biochemistry and evolutionary biology to investigate how toxicity and interactions with Passiflora plants has shaped the evolution of these butterflies. Thus, I will combine the gene-editing technology CRISPR-Cas with different OMICs approaches (metabolomics, transcriptomics and phenomics) to (1) decipher the genetic and phenotipic bases of cyanogenesis in Heliconius butterflies and (2) unravel the evolutionary trajectory of this defence system in the Heliconiine tribe. Moreover, I will also (3) establish how cyanogenesis vary within and between tropical and subtropical heliconiine-Passiflora communities of the Brazilian Atlantic Forest, a biodiversity hotspot endangered by extreme deforestation. This project will give me the unique opportunity to expand my knowledge and skills repertoire on genetics, ecology, evolutionary biology and bioinformatics. I will be trained in advanced techniques such CRISPR-Cas, gene expression analysis, R programing, statistical methods applied to community ecology and matabolomics, etc. Also, during this fellowship I will excel my teaching/supervision, project management and communication abilities. All these expertise will be extremely valuable for the execution of the project and will bring great progress to my career development, increasing my chance of of reaching a long-term position in academia.

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The information about "CYANIDE EVOLUTION" are provided by the European Opendata Portal: CORDIS opendata.

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