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Cyanide Evolution SIGNED

EVOLUTION OF CYANIDE METABOLIMS IN APOSEMATIC BUTTERFLIES: from gene characterization to community ecology

Total Cost €

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EC-Contrib. €

0

Partnership

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 Cyanide Evolution project word cloud

Explore the words cloud of the Cyanide Evolution project. It provides you a very rough idea of what is the project "Cyanide Evolution" about.

larval    extremely    cyanogenic    cas    programing    expression    phenomics    plants    passiflora    give    mimicry    atlantic    matabolomics    brings    biosynthesize    reaching    co    heliconiine    multidisciplinary    colourful    of    ecology    releasing    biochemistry    phenotipic    crispr    career    varies    endangered    academia    defence    fellowship    biodiversity    progress    evolutionary    teaching    butterflies    cyanogenesis    evolution    populations    hotspot    aposematims    metabolomics    glucosides    techniques    skills    editing    tribe    basis    bases    genetic    shaped    unravel    gene    chance    decipher    genetics    forest    unknown    trajectory    brazilian    position    communication    contain    expand    subtropical    valuable    expertise    communities    vary    interactions    biology    repertoire    extreme    combine    excel    feeding    me    trained    toxic    transcriptomics    bioinformatics    community    models    statistical    supervision    toxicity    opportunity    heliconius    tropical    deforestation    compounds    omics    cyanide   

Project "Cyanide Evolution" data sheet

The following table provides information about the project.

Coordinator
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE 

Organization address
address: TRINITY LANE THE OLD SCHOOLS
city: CAMBRIDGE
postcode: CB2 1TN
website: www.cam.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 224˙933 €
 EC max contribution 224˙933 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE UK (CAMBRIDGE) coordinator 224˙933.00

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 Project objective

The colourful and toxic Heliconius butterflies are well-established models to study evolution of aposematims and mimicry, yet the genetic basis of their toxicity and how this varies in different populations remains unknown. Heliconius are toxic butterflies because they contain cyanide-releasing compounds called cyanogenic glucosides, which they can both biosynthesize or uptake from Passiflora plants, their co-evolutionary partner, during larval feeding. This multidisciplinary project brings together ecology, genetics, biochemistry and evolutionary biology to investigate how toxicity and interactions with Passiflora plants has shaped the evolution of these butterflies. Thus, I will combine the gene-editing technology CRISPR-Cas with different OMICs approaches (metabolomics, transcriptomics and phenomics) to (1) decipher the genetic and phenotipic bases of cyanogenesis in Heliconius butterflies and (2) unravel the evolutionary trajectory of this defence system in the Heliconiine tribe. Moreover, I will also (3) establish how cyanogenesis vary within and between tropical and subtropical heliconiine-Passiflora communities of the Brazilian Atlantic Forest, a biodiversity hotspot endangered by extreme deforestation. This project will give me the unique opportunity to expand my knowledge and skills repertoire on genetics, ecology, evolutionary biology and bioinformatics. I will be trained in advanced techniques such CRISPR-Cas, gene expression analysis, R programing, statistical methods applied to community ecology and matabolomics, etc. Also, during this fellowship I will excel my teaching/supervision, project management and communication abilities. All these expertise will be extremely valuable for the execution of the project and will bring great progress to my career development, increasing my chance of of reaching a long-term position in academia.

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The information about "CYANIDE EVOLUTION" are provided by the European Opendata Portal: CORDIS opendata.

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