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KINETICfinder SIGNED

KINETICfinder: A disruptive method to determine kinetic profiles in drug discoveries

Total Cost €

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EC-Contrib. €

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Partnership

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Project "KINETICfinder" data sheet

The following table provides information about the project.

Coordinator
ENZYMLOGIC SL 

Organization address
address: C/ SANTIAGO GRISOLIA 2 RECINTO PARQUE TECNOLOGIC
city: TRES CANTOS MADRID
postcode: 28760
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2019-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ENZYMLOGIC SL ES (TRES CANTOS MADRID) coordinator 50˙000.00

Map

 Project objective

Bringing Bringing a new drug to the market costs 2,600 M€ and it takes 12 years. In addition, around 80% of drugs under research do not reach clinical trials (due to toxicity or lack of efficacy). ENZYMLOGIC was created with the aim of being a company in the niche of kinetic analysis. They have developed KINETICfinder: an experimental, robust, accurate and reproducible methodology that provides drug kinetic analyses in a massive way and at affordable cost, so it is possible to utilise it in early research stages, when thousands of drugs are involved. ENZYMLOGIC has been focused on providing auxiliar external analysis having pharmaceutical companies as customers. Nowadays, there are no comparable technologies capables of generating this amount of information with this level of processivity (number of drugs analysed at the same time). Currently, this analysis is extremely slow and costly, thus it is carried out in the final stages of the research, with just a small number of drugs. Otherwise, the number of different drugs they can analyse is 10 times higher and 10 times faster than other kinetic analysis (processivity). KINETICfinder can reduce the time and cost by 50% from the research phase of a new drug to the market phase. KINETICfinder already makes it possible to analyse 30 kinase targets (involved in cancer), and the next step is to work with GPCRs (neurodegenerative disorders, inflammation, pain, cardiovascular diseases and diabetes). 40% of the existing drugs are aimed at GPCRs. ENZYMLOGIC has obtained several prizes recognizing innovation and potential growth. The objective in phase I will be the validation of the use of KINETICfinder for working with GPCRs having as a base the previous work performed with kinases. To achieve this, the associated tasks shall be: validation of the method working with GPCRs having as a base the previous work performed with kinases, detailed market study & business plan elaboration and validation of commercialization strategy.

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The information about "KINETICFINDER" are provided by the European Opendata Portal: CORDIS opendata.

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