Explore the words cloud of the PhotoXLink project. It provides you a very rough idea of what is the project "PhotoXLink" about.
The following table provides information about the project.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
|Coordinator Country||France [FR]|
|Total cost||184˙707 €|
|EC max contribution||184˙707 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2019-07-01 to 2021-06-30|
Take a look of project's partnership.
|1||CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS||FR (PARIS)||coordinator||184˙707.00|
The PhotoXLink project aims to develop original tools to elucidate the role of various AMPA receptor mediated forms of plasticity in both physiological and pathological situations. AMPAR is a transmembrane ionotropic receptor for glutamate molecule that mediates most fast excitatory synaptic transmission in the mammalian central nervous system. Its regulation is vital for their synaptic function, which underlies memory and learning theories. In the PhotoXLink project, we propose to engineer novel optogenetic tools (photocrosslinkers) that will specifically recognize AMPAR subunits and control their oligomeric state with spatial and temporal resolution. The photocrosslinkers will hence provide a unique control locally, acutely and in a reversible manner on the mobility and local number of AMPARs. The development of these photocrosslinkers will address current technical limitations and ultimately allow investigating with an unprecedented spatiotemporal resolution the impact of AMPARs mobility in short and long term plasticity in the brain function. The multidisciplinary nature of the project is strong, involving molecular/cell biology, biochemistry and protein engineering for the design and production of the tools and advanced fluorescence imaging techniques for validating them in cellular context. It will be carried out at an internationally recognized neuroscience institute that will enhance my skills and diversify my individual competences through advanced training and quality research for improving my future career development. My expertise in photochemistry and photobiology combined with the host´s in neurobiology and protein engineering ensures the best chance for successfully fulfil the goals of the PhotoXLink project. This project is in line with the brain research priority for EU research funding.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "PHOTOXLINK" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "PHOTOXLINK" are provided by the European Opendata Portal: CORDIS opendata.
Non-covalent photoresponsive tags for photoacoustic imaging: Giving voice to living matterRead More
Probing many-body localization dynamics using ultracold fermions in an optical latticeRead More
Gender Violence and Security in the Interoceanic Industrial Corridor of the Isthmus of Tehuantepec: A Critical Examination of Policies and PracticesRead More