Opendata, web and dolomites

MaxONCO SIGNED

A cancer vaccine to boost body’s natural defences to fight chordoma and head and neck cancer

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MaxONCO project word cloud

Explore the words cloud of the MaxONCO project. It provides you a very rough idea of what is the project "MaxONCO" about.

switzerland    grow    data    prepare    types    limited    glands    market    biological    compare    25    commercialization    point    care    line    antigens    accounting    mouth    cells    swissmedic    approval    vaccine    primary    indications    plans    encouraging    globally    cancer    45    profile    drugs    survived    2018    rare    develops    time    indirect    cell    salivary    opportunity    group    released    acting    biotech    immuno    spine    swiss    autologous    private    throat    situ    trial    initiated    initial    chordoma    fda    neck    sites    genetically    positive    first    breakthrough    showed    occurs    trials    diagnosed    designation    head    modified    usa    treatment    anywhere    rate    radiotherapy    safety    base    indication    drug    standard    fast    besides    immunotherapy    source    benign    track    clinical    investigational    perform    immune    approved    shown    orphan    patients    efficacy    treat    agent    maxonco    boost    jobs    maxivax    therapy    benefit    stage    company    650    cancers    ind    sme    skull    showing    surgery    employees   

Project "MaxONCO" data sheet

The following table provides information about the project.

Coordinator
MAXIVAX SA 

Organization address
address: RUE DE LATHEENEE 24
city: GENEVA
postcode: 1206
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 3˙979˙000 €
 EC max contribution 2˙785˙300 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-2
 Funding Scheme SME-2
 Starting year 2020
 Duration (year-month-day) from 2020-01-01   to  2022-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    MAXIVAX SA CH (GENEVA) coordinator 2˙785˙300.00

Map

 Project objective

MaxiVAX a private Swiss clinical-stage biotech company with a novel cancer immunotherapy product in development (MaxONCO) will perform two Phase 2 clinical trials in two indications (Head & Neck, and Chordoma) and prepare the commercialization of MaxONCO, its first immuno-therapy product. The objective of the Phase II clinical trials is to demonstrate efficacy and safety of MaxONCO in the patients treated and compare the results to the current standard of care. MaxONCO is a biological product acting as a cancer vaccine and composed of (i) an immune boost agent released in situ by a genetically modified cell line and (ii) cancer autologous cells, which are the source of antigens. A Phase 1 trial in 25 patients with a range of cancer types at an advanced stage showed encouraging efficacy data and a benign safety profile of the treatment. Head and Neck cancer is a group of cancers that develops in the areas of the head and neck which include the mouth, throat and salivary glands; accounting for 650,000 new cases in 2018 diagnosed globally. With the approval of Swissmedic, MaxiVAX has initiated the Phase 2 clinical trial to evaluate MaxONCO in 40-45 patients with Head & Neck cancer. The study will be conducted across 4-6 different sites in Switzerland. Encouraging clinical results show that among 4 initial Head & Neck patients treated with MaxONCO all survived beyond the 6-month time point (primary efficacy end point). Chordoma is a rare type of cancer that occurs in the skull base and anywhere along the spine. Besides surgery and radiotherapy that are showing only limited success, there are currently no approved drugs to treat Chordoma. In the Phase 1 clinical trial, MaxONCO, has shown promising effects on chordoma patients. A phase 2 Chordoma clinical trial will be conducted in the EU and USA, under an FDA investigational new drug application (IND). A positive overall response rate in Chordoma would allow MaxONCO to benefit from the breakthrough therapy designation as fast-track market opportunity, Chordoma being an orphan indication. Currently accounting for 8 employees, the company plans to grow up to 25 employees by the end of the SME phase 2 project, creating up to 30 indirect jobs.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MAXONCO" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MAXONCO" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.3.;H2020-EU.2.3.;H2020-EU.2.1.)

PREDICT (2019)

Big Data EEG-Analysis for Advanced Personalised Medicine in Depression

Read More  

DetectInMen (2019)

Infection detection in human semen

Read More  

ELDICO ED (2019)

ELDICO ED, Shaping the Future of Crystallography - The First Pure Electron Diffraction Equipment for Nano-Crystallography

Read More