Explore the words cloud of the EPIDEMIC project. It provides you a very rough idea of what is the project "EPIDEMIC" about.
The following table provides information about the project.
UNIVERSITE DE LAUSANNE
|Coordinator Country||Switzerland [CH]|
|Total cost||1˙500˙000 €|
|EC max contribution||1˙500˙000 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2020-08-01 to 2025-07-31|
Take a look of project's partnership.
|1||UNIVERSITE DE LAUSANNE||CH (LAUSANNE)||coordinator||1˙500˙000.00|
The risks and impact of disease are exacerbated in social organisms, which live in dense groups wherein pathogens can rapidly propagate. Theoretical epidemiology predicts that disease dynamics will depend in large part on a group's social interaction network, but empirical data are scarce. Experimental epidemiology is currently hampered by a lack of study systems that would enable a rigorous investigation of the causal link between network structure and disease transmission.
I will tackle this question using a novel system, the clonal raider ant, a social insect whose unique biology affords unparalleled control over the main aspects of colony composition that are thought to modulate social network structure, and therefore, disease transmission. My approach will combine cutting-edge automated techniques for behavioral tracking with molecular tools, and develop new methods to monitor transmission in real time. In a first step, I will create empirical networks that are theoretically predicted to vary in transmission risk and map individual immune function onto these networks, to measure the prophylactic network properties that might reduce disease transmission. Second, I will test if experimental increases in immune activity induce changes in behavior that are relevant for disease transmission, to measure inducible network properties. Finally, I will inoculate colonies with nematodes and quantify infection propagation in real time. This will allow me to compare various types of social networks (healthy, immune-activated, infected), to probe the link between behavior and immunity, and to experimentally test predictions from theoretical epidemiology.
This project takes an integrative approach—from individual immunity to collective behavior—to uncover the properties of social groups that protect them against disease. By linking theoretical epidemiology to real-world disease dynamics, it will push the limits of our ability to predict disease dynamics in social groups.
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The information about "EPIDEMIC" are provided by the European Opendata Portal: CORDIS opendata.
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