Explore the words cloud of the STARSS project. It provides you a very rough idea of what is the project "STARSS" about.
The following table provides information about the project.
KUNGLIGA TEKNISKA HOEGSKOLAN
|Coordinator Country||Sweden [SE]|
|Total cost||191˙852 €|
|EC max contribution||191˙852 € (100%)|
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
|Duration (year-month-day)||from 2020-04-01 to 2022-03-31|
Take a look of project's partnership.
|1||KUNGLIGA TEKNISKA HOEGSKOLAN||SE (STOCKHOLM)||coordinator||191˙852.00|
Viable experimental techniques able to reveal and quantify protein-protein interactions and protein conformational changes can have a significant impact on cell biology and drug discovery. Fluorescence anisotropy (FA) has been widely employed in biomedical research as a tool for high-throughput screening applications, to study the binding of small molecules to protein and characterize protein-protein interaction. Despite the enormous potential of the FA technique, the major limiting factor is the inability of probing the system past the fluorescence lifetime, which in the most favorable cases lasts for a few nanoseconds, setting an upper limit to the time scales that can be addressed with the technique, which translates in an upper limit of few nanometers of molecular size. Reversibly switchable fluorescent transitions have the potential to revolutionize the capability of FA tools for the study of large molecular aggregates, overcoming the limits imposed by the finite fluorescence lifetime, and providing a practical and highly sensible way of measuring rotational diffusion processes with a practically unlimited upper bound on molecular sizes. This proposal aims to develop a novel fluorescent anisotropy technique, named Super Time-resolved Anisotropy with Reversibly Switchable States (STARSS), designed to measure rotational mobility all-across the time scale from nano- to micro-seconds, which will enable to discern clusters from free rotating molecules in situ and with high angular precision. The coupling of STARSS observables and microscopy will provide a powerful tool to reveal the dynamics of protein complexes inside the compartments of living cells, shedding new light on a multitude of biological processes.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "STARSS" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (firstname.lastname@example.org) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "STARSS" are provided by the European Opendata Portal: CORDIS opendata.
Strongly Interacting Mass Imbalanced Superfluid with ultracold fermionsRead More
The multi-omics role of lipid transfer proteins in lipid metabolismRead More
Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and IconographyRead More