Opendata, web and dolomites

MiMoZa SIGNED

Microbiota modulation through horizontal gene transfer.

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 MiMoZa project word cloud

Explore the words cloud of the MiMoZa project. It provides you a very rough idea of what is the project "MiMoZa" about.

nor    pressure    transfer    altering    policies    gut    serve    metagenomic    influencing    led    microbes    successes    fellowship    connected    stimulate    prokaryotes    horizontal    gm    limit    lifestyle    gastro    strategies    functions    implications    rates    difficult    brito    stay    spread    composition    selective    jeroen    infection    species    intestinal    ilana    strain    changing    medication    sizes    realization    human    transgenes    additional    transit    abundances    residing    lab    time    diet    gene    examine    modulation    raes    transfers    initial    microbiome    material    experimentally    bodies    myriad    exchange    genetic    antibiotic    modulate    successful    my    tract    microbiota    function    effect    competition    alternative    natural    hgt    dna    contacted    difficile    immune    little    ways    datasets    msca    animal    host    despite    treatment    possibilities    environments    intimately    small    health    fecal    probiotic    relative    dietary    resident    cocktails    agricultural    engraftment   

Project "MiMoZa" data sheet

The following table provides information about the project.

Coordinator
VIB 

Organization address
address: RIJVISSCHESTRAAT 120
city: ZWIJNAARDE - GENT
postcode: 9052
website: www.vib.be

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Belgium [BE]
 Total cost 266˙425 €
 EC max contribution 266˙425 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-GF
 Starting year 2020
 Duration (year-month-day) from 2020-08-01   to  2023-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    VIB BE (ZWIJNAARDE - GENT) coordinator 266˙425.00
2    CORNELL UNIVERSITY US (ITHACA NY) partner 0.00

Map

 Project objective

My goal is to determine horizontal gene transfer (HGT) rates of specific functions within the gut microbiome. The microbes on and within our bodies, especially within our gastro-intestinal tract, are intimately connected with our immune system and promote health in myriad ways. Altering our gut microbiota (GM) composition and/or function might thus improve health. My research in the Jeroen Raes lab led to the realization that changing species abundances through dietary or lifestyle modulation may be difficult because of the small effect sizes of the factors influencing GM composition (e.g. diet, medication, or transit time). In addition, host-selection and competition of resident microbes, might limit the strain engraftment necessary for the effect of fecal transfers and probiotic cocktails. Despite initial successes (e.g. C. difficile infection treatment), current modulation strategies might therefore be less successful with other conditions. I contacted Ilana Brito, in order to find out whether HGT - a process in which prokaryotes exchange genetic material - may serve as an alternative way to modulate the residing GM. Little is known about the features that affect HGT rates within natural environments nor the role of selection in that process. If these were well-understood, it would allow to assess the possibilities of extending the gut microbiome with additional functions. During my research stay, I will experimentally determine HGT rates within the animal gut under natural and HGT-enhancing conditions. In addition, I will develop methods to examine HGT in metagenomic datasets and determine the relative importance of the factors influencing HGT (selective pressure, host health and DNA delivery method). The knowledge generated through this MSCA-fellowship will stimulate the development of novel GM modulation strategies and will have important implications for human health and agricultural policies (e.g. antibiotic use, spread of transgenes).

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MIMOZA" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MIMOZA" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

CORRELATION (2020)

Characterization and prediction of service-level traffic for future sliced mobile network

Read More  

Photonic Radar (2019)

Implementation of Long Reach Hybrid Photonic Radar System and convergence over FSO and PON Networks

Read More  

STOPFIRE (2019)

Emergency Decision Support System of Offshore Platform Fires

Read More