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USOME SIGNED

Advanced Analysis of Polymersome and Exosome Hybrids for Potential Application in Therapeutics and Diagnostics

Total Cost €

0

EC-Contrib. €

0

Partnership

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 USOME project word cloud

Explore the words cloud of the USOME project. It provides you a very rough idea of what is the project "USOME" about.

nano    detectors    combination    encapsulation    customized    biohybrid    create    international    diagnostic    representing    relationships    analytical    exosome    training    diagnostics    polymersomes    structural    scientific    counterparts    hold    individual    fellowship    performed    envisaged    tools    researcher    promise    material    biohybrids    variation    modification    usome    hybrids    flow    society    techniques    natural    compositional    exosomes    expertise    curiosity    materials    characterization    chances    topical    sufficiently    doors    unlocks    ipf    benefits    structure    therapeutics    african    progress    origin    multiple    fronteers    biological    polymers    biohybid    community    excellent    proteins    talented    distributions    fractionation    fundamental    indicate    outstanding    elucidation    young    model    breakthrough    profile    er    synthetic    technique    patients    compartments    drug    hybrid    coupled    proper    career    stability    functionalisation    entirely    polymersome    vesicles   

Project "USOME" data sheet

The following table provides information about the project.

Coordinator		 LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV 

Organization address
address: HOHE STRASSE 6
city: DRESDEN
postcode: 1069
website: www.ipfdd.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country Germany [DE]
 Total cost 162˙806 €
 EC max contribution 162˙806 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-05-01   to  2022-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV DE (DRESDEN) coordinator 162˙806.00

Map

 Project objective

Biological vesicles hold great promise as nano compartments for various applications such as drug delivery systems, therapeutics, and diagnostic tools but fundamental relationships between material properties and activity are not sufficiently understood to create new products for the benefits of the European society. The overall aim of USOME is to develop characterization approaches for these novel materials enabling proper functionalisation. In particular, this proposal focuses on the development of an entirely novel analytical approach for the analysis of emerging biohybrid vesicles. As model systems we indicate polymersome-hybrids and exosome-hybrids, representing a variation in structure in terms of stability, origin (synthetic/natural) and their hybrid counterparts (proteins/synthetic polymers). Two processes will be studied in detail (i) the encapsulation of proteins in polymersomes; and (ii) the modification of exosomes with proteins and polymers. As a result, advanced analytical methods for characterization of polymersome and exosome hybrids for potential application in therapeutics and diagnostics will be established. The key to this envisaged breakthrough is based on field flow fractionation technique coupled to multiple detectors for elucidation of the structural and compositional distributions in the biohybid systems. This highly topical research will be performed within the individual fellowship of a young, very talented, and curiosity-driven African researcher in a leading European research institute. The combination of his expertise in analytical techniques, the biohybrids formation knowledge of IPF and specific knowledge of the associated partners will enable significant scientific progress in the field and unlocks value for patients. Excellent, customized training will open the ER the doors to a unique research profile, fully embedded in the international scientific community and with outstanding career chances at the fronteers of research.

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The information about "USOME" are provided by the European Opendata Portal: CORDIS opendata.

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