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Advanced Analysis of Polymersome and Exosome Hybrids for Potential Application in Therapeutics and Diagnostics

Total Cost €


EC-Contrib. €






 USOME project word cloud

Explore the words cloud of the USOME project. It provides you a very rough idea of what is the project "USOME" about.

er    diagnostic    african    sufficiently    fellowship    patients    synthetic    combination    career    scientific    techniques    materials    customized    compositional    hold    community    proper    expertise    natural    variation    diagnostics    performed    polymers    topical    excellent    distributions    multiple    origin    young    fractionation    hybrids    proteins    biohybid    profile    indicate    create    curiosity    stability    society    breakthrough    drug    progress    relationships    unlocks    fronteers    outstanding    international    chances    training    analytical    individual    envisaged    structural    flow    vesicles    therapeutics    coupled    material    structure    representing    functionalisation    researcher    hybrid    modification    doors    compartments    elucidation    entirely    biohybrid    polymersome    ipf    exosome    nano    promise    biohybrids    detectors    biological    counterparts    polymersomes    technique    benefits    talented    tools    encapsulation    exosomes    model    characterization    usome    fundamental   

Project "USOME" data sheet

The following table provides information about the project.


Organization address
address: HOHE STRASSE 6
postcode: 1069

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 162˙806 €
 EC max contribution 162˙806 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-05-01   to  2022-04-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Biological vesicles hold great promise as nano compartments for various applications such as drug delivery systems, therapeutics, and diagnostic tools but fundamental relationships between material properties and activity are not sufficiently understood to create new products for the benefits of the European society. The overall aim of USOME is to develop characterization approaches for these novel materials enabling proper functionalisation. In particular, this proposal focuses on the development of an entirely novel analytical approach for the analysis of emerging biohybrid vesicles. As model systems we indicate polymersome-hybrids and exosome-hybrids, representing a variation in structure in terms of stability, origin (synthetic/natural) and their hybrid counterparts (proteins/synthetic polymers). Two processes will be studied in detail (i) the encapsulation of proteins in polymersomes; and (ii) the modification of exosomes with proteins and polymers. As a result, advanced analytical methods for characterization of polymersome and exosome hybrids for potential application in therapeutics and diagnostics will be established. The key to this envisaged breakthrough is based on field flow fractionation technique coupled to multiple detectors for elucidation of the structural and compositional distributions in the biohybid systems. This highly topical research will be performed within the individual fellowship of a young, very talented, and curiosity-driven African researcher in a leading European research institute. The combination of his expertise in analytical techniques, the biohybrids formation knowledge of IPF and specific knowledge of the associated partners will enable significant scientific progress in the field and unlocks value for patients. Excellent, customized training will open the ER the doors to a unique research profile, fully embedded in the international scientific community and with outstanding career chances at the fronteers of research.

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