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USOME SIGNED

Advanced Analysis of Polymersome and Exosome Hybrids for Potential Application in Therapeutics and Diagnostics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 USOME project word cloud

Explore the words cloud of the USOME project. It provides you a very rough idea of what is the project "USOME" about.

polymers    curiosity    vesicles    researcher    nano    hybrids    encapsulation    coupled    scientific    chances    promise    biological    proteins    compartments    er    detectors    structure    outstanding    usome    representing    progress    patients    exosomes    tools    exosome    benefits    expertise    international    biohybrid    polymersomes    technique    topical    counterparts    community    analytical    individual    therapeutics    young    training    diagnostics    hold    flow    characterization    material    compositional    entirely    model    customized    natural    career    breakthrough    drug    combination    polymersome    modification    fundamental    fronteers    relationships    unlocks    multiple    biohybid    materials    variation    diagnostic    indicate    origin    structural    doors    functionalisation    hybrid    talented    elucidation    performed    excellent    distributions    african    society    create    envisaged    fellowship    proper    fractionation    sufficiently    techniques    synthetic    biohybrids    profile    stability    ipf   

Project "USOME" data sheet

The following table provides information about the project.

Coordinator
LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV 

Organization address
address: HOHE STRASSE 6
city: DRESDEN
postcode: 1069
website: www.ipfdd.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 162˙806 €
 EC max contribution 162˙806 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-05-01   to  2022-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV DE (DRESDEN) coordinator 162˙806.00

Map

 Project objective

Biological vesicles hold great promise as nano compartments for various applications such as drug delivery systems, therapeutics, and diagnostic tools but fundamental relationships between material properties and activity are not sufficiently understood to create new products for the benefits of the European society. The overall aim of USOME is to develop characterization approaches for these novel materials enabling proper functionalisation. In particular, this proposal focuses on the development of an entirely novel analytical approach for the analysis of emerging biohybrid vesicles. As model systems we indicate polymersome-hybrids and exosome-hybrids, representing a variation in structure in terms of stability, origin (synthetic/natural) and their hybrid counterparts (proteins/synthetic polymers). Two processes will be studied in detail (i) the encapsulation of proteins in polymersomes; and (ii) the modification of exosomes with proteins and polymers. As a result, advanced analytical methods for characterization of polymersome and exosome hybrids for potential application in therapeutics and diagnostics will be established. The key to this envisaged breakthrough is based on field flow fractionation technique coupled to multiple detectors for elucidation of the structural and compositional distributions in the biohybid systems. This highly topical research will be performed within the individual fellowship of a young, very talented, and curiosity-driven African researcher in a leading European research institute. The combination of his expertise in analytical techniques, the biohybrids formation knowledge of IPF and specific knowledge of the associated partners will enable significant scientific progress in the field and unlocks value for patients. Excellent, customized training will open the ER the doors to a unique research profile, fully embedded in the international scientific community and with outstanding career chances at the fronteers of research.

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The information about "USOME" are provided by the European Opendata Portal: CORDIS opendata.

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