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USOME SIGNED

Advanced Analysis of Polymersome and Exosome Hybrids for Potential Application in Therapeutics and Diagnostics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 USOME project word cloud

Explore the words cloud of the USOME project. It provides you a very rough idea of what is the project "USOME" about.

talented    technique    distributions    progress    functionalisation    characterization    variation    society    training    sufficiently    create    fractionation    indicate    model    young    representing    community    tools    polymersome    fundamental    hybrid    customized    biohybrids    entirely    biological    researcher    hold    biohybrid    outstanding    encapsulation    structural    performed    usome    fronteers    patients    counterparts    doors    techniques    vesicles    stability    chances    polymersomes    polymers    flow    profile    detectors    promise    curiosity    unlocks    material    drug    hybrids    proper    diagnostics    relationships    benefits    african    diagnostic    excellent    proteins    coupled    envisaged    synthetic    scientific    exosomes    nano    materials    international    natural    breakthrough    therapeutics    compartments    career    combination    compositional    structure    origin    modification    ipf    multiple    analytical    exosome    individual    expertise    er    biohybid    fellowship    elucidation    topical   

Project "USOME" data sheet

The following table provides information about the project.

Coordinator
LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV 

Organization address
address: HOHE STRASSE 6
city: DRESDEN
postcode: 1069
website: www.ipfdd.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Total cost 162˙806 €
 EC max contribution 162˙806 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-05-01   to  2022-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV DE (DRESDEN) coordinator 162˙806.00

Map

 Project objective

Biological vesicles hold great promise as nano compartments for various applications such as drug delivery systems, therapeutics, and diagnostic tools but fundamental relationships between material properties and activity are not sufficiently understood to create new products for the benefits of the European society. The overall aim of USOME is to develop characterization approaches for these novel materials enabling proper functionalisation. In particular, this proposal focuses on the development of an entirely novel analytical approach for the analysis of emerging biohybrid vesicles. As model systems we indicate polymersome-hybrids and exosome-hybrids, representing a variation in structure in terms of stability, origin (synthetic/natural) and their hybrid counterparts (proteins/synthetic polymers). Two processes will be studied in detail (i) the encapsulation of proteins in polymersomes; and (ii) the modification of exosomes with proteins and polymers. As a result, advanced analytical methods for characterization of polymersome and exosome hybrids for potential application in therapeutics and diagnostics will be established. The key to this envisaged breakthrough is based on field flow fractionation technique coupled to multiple detectors for elucidation of the structural and compositional distributions in the biohybid systems. This highly topical research will be performed within the individual fellowship of a young, very talented, and curiosity-driven African researcher in a leading European research institute. The combination of his expertise in analytical techniques, the biohybrids formation knowledge of IPF and specific knowledge of the associated partners will enable significant scientific progress in the field and unlocks value for patients. Excellent, customized training will open the ER the doors to a unique research profile, fully embedded in the international scientific community and with outstanding career chances at the fronteers of research.

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The information about "USOME" are provided by the European Opendata Portal: CORDIS opendata.

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