PHASETOMO

Development of a three-dimensional Reconstruction Algorithm for Phase Contrast Breast Tomosynthesis

Coordinatore	TECHNICAL UNIVERSITY OF VARNA    more  Organization address address: Studentska 1 city: VARNA postcode: 9010 contact info Titolo: Prof. Nome: Ivan Cognome: Buliev Email: send email Telefono: +359 52 383572
Nazionalità Coordinatore	Bulgaria [BG]
Totale costo	100˙000 €
EC contributo	100˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2011-CIG
Funding Scheme	MC-CIG
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-09-01   -   2016-08-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	TECHNICAL UNIVERSITY OF VARNA  Organization address address: Studentska 1 city: VARNA postcode: 9010 contact info Titolo: Prof. Nome: Ivan Cognome: Buliev Email: send email Telefono: +359 52 383572	BG (VARNA)	coordinator	100˙000.00

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 Obiettivo del progetto (Objective)

'Breast cancer remains the most common cause of death for women below seventy years of age. In Europe, one in ten women will develop breast cancer in her lifetime. Early diagnosis is recognised as a critical factor that can improve the chance of survival. X-ray mammography is currently considered best practice for screening and early diagnosis of breast carcinoma. However, a significant number of breast cancers remain undetected when using conventional 2D mammography imaging, due to insufficient soft tissue contrast and the effect of overlying anatomical structures.

A method that combines the advantages of the phase contrast imaging and digital breast tomosynthesis may result in high contrast tomograms with well outlined breast cancer margins.

This project will aim to develop, test and validate a three-dimensional reconstruction algorithm for phase contrast digital breast tomosynthesis. The overall objective will be pursued through the following specific objectives that will be addressed in a number of highly innovative tasks of design, modelling, numerical simulations and experimental work: (a) Development of a simulation tool for generation of phase contrast images over limited angular range; (b) Development of a three-dimensional algorithm for phase contrast breast tomosynthesis; (c) Validation and further refinement of the algorithm with computer models of ground truth phantoms as well with physical phantoms that will be exploited at laboratory environment.

The availability of three-dimensional reconstruction algorithms dedicated for phase contrast breast tomosynthesis will provide a possibility to study the potential of this novel technique to enhance contours of different breast soft tissues, thus resulting in clearly visible three dimensional soft tissue morphology.'