OPTI-CLEAN

Effective and reliable optical system for cleaning validation in pharmaceuticals manufacture

 Coordinatore INNOPHARMA LABS LIMITED 

 Organization address address: ASHFIELD CRONE LOWER
city: REDCROSS

contact info
Titolo: Mr.
Nome: Ian
Cognome: Jones
Email: send email
Telefono: +353 863422314

 Nazionalità Coordinatore Ireland [IE]
 Totale costo 1˙489˙301 €
 EC contributo 1˙149˙720 €
 Programma FP7-SME
Specific Programme "Capacities": Research for the benefit of SMEs
 Code Call FP7-SME-2011
 Funding Scheme BSG-SME
 Anno di inizio 2011
 Periodo (anno-mese-giorno) 2011-11-01   -   2013-10-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    INNOPHARMA LABS LIMITED

 Organization address address: ASHFIELD CRONE LOWER
city: REDCROSS

contact info
Titolo: Mr.
Nome: Ian
Cognome: Jones
Email: send email
Telefono: +353 863422314

IE (REDCROSS) coordinator 678˙282.00
2    RIKOLA LTD OY

 Organization address address: KAITOVAYLA 1
city: OULU
postcode: 90570

contact info
Titolo: Mr.
Nome: Rikola
Cognome: Raimo
Email: send email
Telefono: 358405000000

FI (OULU) participant 181˙302.00
3    KUAVA OY

 Organization address address: MICROKATU 1
city: KUOPIO
postcode: 70210

contact info
Titolo: Mr.
Nome: Antti
Cognome: Vanne
Email: send email
Telefono: +358 50 3566744

FI (KUOPIO) participant 138˙760.00
4    MANUFACTURAS SERVIPLAST SA

 Organization address address: CL COBALTO 13
city: Hospitalet Llobregat
postcode: 8907

contact info
Titolo: Mr.
Nome: Enrique
Cognome: Romero
Email: send email
Telefono: +3493 337 72 48

ES (Hospitalet Llobregat) participant 115˙769.00
5    DUBLIN INSTITUTE OF TECHNOLOGY

 Organization address address: RATHMINES ROAD LOWER 143-149
city: DUBLIN
postcode: 6

contact info
Titolo: Dr.
Nome: Pj
Cognome: Cullen
Email: send email
Telefono: 35314208016

IE (DUBLIN) participant 12˙800.00
6    INNOVACIO I RECERCA INDUSTRIAL I SOSTENIBLE SL

 Organization address address: AVENIDA DEL CANAL OLIMPIC 15 PARC MEDITERRANI DE LA TECNOLOGIA EDIFICIO C4 BLOQUE ANEXO PLANTA BAJA
city: Castelldefels
postcode: 8860

contact info
Titolo: Mr.
Nome: Digby
Cognome: Colm
Email: send email
Telefono: +34 935542500

ES (Castelldefels) participant 10˙282.00
7    MERRION PHARMACEUTICALS IRELAND LTD

 Organization address address: "LAKE DRIVE, CITYWEST BUSINESS CAMPUS 3200"
city: DUBLIN
postcode: 24

contact info
Titolo: Mr.
Nome: Brian
Cognome: Boland
Email: send email
Telefono: +353 1 6423301

IE (DUBLIN) participant 6˙480.00
8    TEKNOLOGIAN TUTKIMUSKESKUS VTT

 Organization address address: TEKNIIKANTIE 4 A
city: ESPOO
postcode: 02044 VTT

contact info
Titolo: Mr.
Nome: Mikko
Cognome: Juuti
Email: send email
Telefono: +358 20 722 2144

FI (ESPOO) participant 6˙045.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

tested    validation    impact    portable    manufacture    industry    device    safety    individual    techniques    detergents    time    pharmaceutical    imaging    contaminants    apis    surfaces    cleaning    plants    real   

 Obiettivo del progetto (Objective)

'Cleaning validation in the pharmaceutical industry is the verification that the cleaning procedure used to remove contaminants from equipment surfaces is successfully reproducible. In pharmaceutical manufacture, plants or individual pieces of equipment may be dedicated to individual products or indeed used in multi-product manufacture. Cleaning should be carried out as soon as practical after the end of processing and should leave the plant in a suitable condition for next use. The impact of inadequate cleaning procedures is that any of a number of contaminants may be present in the next batch manufactured on the equipment. Current cleaning validation techniques are largely based on laborious, time consuming and expensive swab sampling techniques, whereby swabs of the cleaned surface are taken and then tested using HPLC techniques in the laboratory. Equipment can be down for days, which poses enormous economic burden in the pharmaceutical industry.

The proposed project will build on the promising results of preliminary research using NIR Chemical Imaging technology to detect on surfaces low concentrations of APIs and detergents used in pharmaceutical manufacture. The results have shown the feasibility of such technology to be used to provide accurate information in real-time, thereby opening up the possibility for the development of a custom-made version of the technology that could be trialled and validated for its use in the pharmaceutical industry as a cleaning validation tool. A portable imaging device will be designed and built and tested on a commonly used APIs and detergents in real pharmaceutical environments in order to validate its effectiveness and reliability. The impact of the uptake of the technology will enable rapid turn-around times, increased through-put and profitability in EU pharmaceutical plants, as well as increased safety standards, which are paramount to safeguarding the health and safety of EU citizens.'

Introduzione (Teaser)

Pharmaceutical and biotechnology manufacturers must ensure that equipment is free of contamination before beginning a new production run. A novel portable device exploiting infrared technology could make that process much more reliable.

Altri progetti dello stesso programma (FP7-SME)

SENSBIOSYN (2009)

Biosensors and Sensors for the industrial biosynthesis process of widely used commercial antioxidants: nutraceuticals as additives for food and aquaculture promoting public health and safety

Read More  

GPRIX (2009)

Good Practices in Innovation Support Measures for SMEs: facilitating transition from the traditional to the knowledge economy

Read More  

HERMES (2012)

"Innovative, Highly Efficient Road Surface Measurement and Control System"

Read More