FURSEALFITNESS

Elucidating the relationship between heterozygosity and fitness in a natural marine mammal population

Coordinatore	UNIVERSITAET BIELEFELD    more  Organization address address: UNIVERSITAETSSTRASSE 25 city: BIELEFELD postcode: 33615 contact info Titolo: Ms. Nome: Iris Cognome: Litty Email: send email Telefono: +49 521 1062569 Fax: +49 521 1066445
Nazionalità Coordinatore	Germany [DE]
Totale costo	100˙000 €
EC contributo	100˙000 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2011-CIG
Funding Scheme	MC-CIG
Anno di inizio	2012
Periodo (anno-mese-giorno)	2012-04-01   -   2016-03-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	UNIVERSITAET BIELEFELD  Organization address address: UNIVERSITAETSSTRASSE 25 city: BIELEFELD postcode: 33615 contact info Titolo: Ms. Nome: Iris Cognome: Litty Email: send email Telefono: +49 521 1062569 Fax: +49 521 1066445	DE (BIELEFELD)	coordinator	100˙000.00

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 Obiettivo del progetto (Objective)

'Many important fitness traits including longevity, reproductive success, parasite resistance, territory-holding ability, song complexity and even attractiveness often correlate with heterozygosity in natural populations. Where documented, such heterozygosity-fitness correlations (HFCs) have the clear potential to influence interactions between pathogens and their hosts and the evolution of mate choice. However, because most studies use only around ten neutral microsatellite markers, the proximate mechanisms underlying HFCs remain obscure. Fortunately, next-generation sequencing approaches now make it possible to sequence DNA cheaply and on a massive scale, allowing large panels of Single Nucelotide Polymorphisms (SNPs) to be developed in virtually any organism. By screening these in the Antarctic fur seal, a model system in which unusually high-quality measures of fitness are available, I will for the first time determine the mechanisms underlying a range of HFCs in a natural population and uncover actual genes linked to variation in key traits including longevity, reproductive success and attractiveness.'