NGRB

Next generation disease resistance breeding in plants

 Coordinatore THE SAINSBURY LABORATORY 

Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie.

 Nazionalità Coordinatore United Kingdom [UK]
 Totale costo 2˙496˙835 €
 EC contributo 2˙496˙835 €
 Programma FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call ERC-2011-ADG_20110310
 Funding Scheme ERC-AG
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-04-01   -   2017-03-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    JOHN INNES CENTRE

 Organization address address: "Norwich Research Park, Colney"
city: NORWICH
postcode: NR4 7UH

contact info
Titolo: Dr.
Nome: Mary
Cognome: Anderson
Email: send email
Telefono: +44 1603 450244
Fax: +44 1603 450045

UK (NORWICH) beneficiary 536˙878.00
2    THE SAINSBURY LABORATORY

 Organization address address: "Norwich Research Park, Colney Lane"
city: NORWICH
postcode: NR47UH

contact info
Titolo: Ms.
Nome: Debbie
Cognome: Feather
Email: send email
Telefono: +44 1603 450420
Fax: +44 1603 450011

UK (NORWICH) hostInstitution 1˙959˙957.00
3    THE SAINSBURY LABORATORY

 Organization address address: "Norwich Research Park, Colney Lane"
city: NORWICH
postcode: NR47UH

contact info
Titolo: Prof.
Nome: Sophien
Cognome: Kamoun
Email: send email
Telefono: +44 1603 450410
Fax: +44 1603 450011

UK (NORWICH) hostInstitution 1˙959˙957.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

expanded    synthetic    effectors    blight    disease    potato    broad    spectrum    infestans    resistant    breeding    recognition    agriculture       plant    resistance    tomato    late    effector    pathogen    genes    generate   

 Obiettivo del progetto (Objective)

'Plant diseases represent a significant threat to global food security. One of the most notorious plant pathogens is the Irish potato famine organism Phytophthora infestans. P. infestans, the causal agent of potato and tomato late blight, continues to cost modern agriculture billions of euros annually. The most sustainable strategy to manage late blight is to breed broad-spectrum disease resistance into potato and tomato. However, current disease resistance breeding approaches are slow, inefficient, and have taken little advantage of emerging knowledge of pathogen mechanisms. Resistance genes have been identified, bred, and deployed in agriculture without detailed knowledge of the effectors they are sensing – a ‘blind’ approach. The overall aim of this proposal is to exploit state of the art findings on pathogen effector biology to drive the development of new approaches to breeding disease resistant crops. Our long-term objective is to generate late blight resistant crop varieties. The central hypothesis of the proposed research is that mutations in plant resistance and effector target genes can result in broad-spectrum resistance to late blight. The rationale behind this research is based on exciting preliminary data that demonstrated (i) there is a core set of effectors in P. infestans; (ii) plant proteins targeted by P. infestans effectors are important components of the immune response; and (iii) single amino acid changes in a potato resistance protein can result in expanded effector recognition. To achieve our goal, we plan to pursue the following specific objectives: 1. Understand the molecular details of how three P. infestans effectors modulate plant immunity. 2. Generate synthetic plant resistance genes with expanded recognition of P. infestans effectors. 3. Generate synthetic plant effector targets with modified interaction with P. infestans effectors. 4. Use the synthetic genes to engineer broad-spectrum late blight resistance.'

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