BOC

The Body-on-a-Chip (BoC)

 Coordinatore INSPHERO AG 

 Organization address address: TECHNOPARKSTRASSE 1
city: ZURICH
postcode: 8005

contact info
Titolo: Dr.
Nome: Jan
Cognome: Lichtenberg
Email: send email
Telefono: 41445150499

 Nazionalità Coordinatore Switzerland [CH]
 Totale costo 1˙919˙000 €
 EC contributo 1˙395˙000 €
 Programma FP7-ICT
Specific Programme "Cooperation": Information and communication technologies
 Code Call FP7-ICT-2011-C
 Funding Scheme CP
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-06-01   -   2015-05-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    INSPHERO AG

 Organization address address: TECHNOPARKSTRASSE 1
city: ZURICH
postcode: 8005

contact info
Titolo: Dr.
Nome: Jan
Cognome: Lichtenberg
Email: send email
Telefono: 41445150499

CH (ZURICH) coordinator 0.00
2    ASTRAZENECA UK LIMITED

 Organization address address: STANHOPE GATE
city: LONDON
postcode: W1K 1LN

contact info
Titolo: Dr.
Nome: Eric
Cognome: Tang
Email: send email
Telefono: +44 1625515781

UK (LONDON) participant 0.00
3    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH

 Organization address address: Raemistrasse
city: ZUERICH
postcode: 8092

contact info
Titolo: Prof.
Nome: Andreas
Cognome: Hierlemann
Email: send email
Telefono: +41 61 387 3150

CH (ZUERICH) participant 0.00
4    FORSCHUNGSGESELLSCHAFT FUR ARBEITSPHYSIOLOGIE UND ARBEITSSCHUTZ E.V.

 Organization address address: ARDEYSTRASSE
city: DORTMUND
postcode: 44139

contact info
Titolo: Prof.
Nome: Jan
Cognome: Hengstler
Email: send email
Telefono: +49 231 1084 348
Fax: +49 231 1084 403

DE (DORTMUND) participant 0.00
5    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt
city: LEUVEN
postcode: 3000

contact info
Titolo: Ms.
Nome: Sofie
Cognome: Heroes
Email: send email
Telefono: +32 16 329979
Fax: +32 16 326515

BE (LEUVEN) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

physiological    drug    body    microtissues    drugs    candidate    liver    tissue    platform    tissues    pharmaceutical    human    related   

 Obiettivo del progetto (Objective)

High attrition and failures rates in pharmaceutical and biotechnological drug development require a paradigm change towards more physiological human cell-based assays at an early time point in the process. The central idea of this proposal is to develop a versatile and reconfigurable pharmaceutical screening technology platform that relies on organotypic three-dimensional spherical microtissues. This platform will accommodate different types of human microtissues (tumor, brain, liver, heart etc.) and feature microfluidic interconnection between these tissues, thus mimicking the physiological context and conditions in a human body. Dosage of components or candidate drugs to, e.g., liver tissue will lead to the generation of metabolic products in the respective tissue compartment. These products then can be routed via the microfluidics to, e.g., connective tissue to assess the efficacy of the candidate drug and related adverse toxicological effects on the target tissue and functionally related tissues. This way, functional connectivity in a real body can be mimicked at the desired level of complexity, and the effects of drugs can be comprehensively assessed.

Altri progetti dello stesso programma (FP7-ICT)

ENCORE (2010)

ENabling technologies for a programmable many-CORE

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E2LP (2012)

Embedded Computer Engineering Learning Platform

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SPaCIoS (2010)

Secure Provision and Consumption in the Internet of Services

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