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NANOMEM

Membrane Protein Nanocrystallography

Coordinatore	GOETEBORGS UNIVERSITET Organization address address: VASAPARKEN city: GOETEBORG postcode: 405 30 contact info Titolo: Ms. Nome: Maria Cognome: Enge Email: send email Telefono: +46 31 786 6473 Fax: +46 31 786 4355
Nazionalità Coordinatore	Sweden [SE]
Totale costo	2˙814˙628 €
EC contributo	2˙814˙628 €
Programma	FP7-PEOPLE Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
Code Call	FP7-PEOPLE-2012-ITN
Funding Scheme	MC-ITN
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-01-01 - 2016-12-31

Partecipanti

#	participant	country	role	EC contrib. [€]
1	GOETEBORGS UNIVERSITET Organization address address: VASAPARKEN city: GOETEBORG postcode: 405 30 contact info Titolo: Ms. Nome: Maria Cognome: Enge Email: send email Telefono: +46 31 786 6473 Fax: +46 31 786 4355	SE (GOETEBORG)	coordinator	557˙469.26
2	PAUL SCHERRER INSTITUT Organization address address: Villigen city: VILLIGEN PSI postcode: 5232 contact info Titolo: Mrs. Nome: Irene Cognome: Walthert Email: send email Telefono: +4156 3102664 Fax: 41563102717	CH (VILLIGEN PSI)	participant	411˙244.90
3	IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ contact info Titolo: Ms. Nome: Brooke Cognome: Alasya Email: send email Telefono: +44 20 7594 1181 Fax: +44 207 594 1418	UK (LONDON)	participant	286˙156.64
4	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Organization address address: Rue Michel -Ange 3 city: PARIS postcode: 75794 contact info Titolo: Mr. Nome: Guillaume Cognome: Rochet Email: send email Telefono: +33 4 76881005 Fax: +33 4 76881174	FR (PARIS)	participant	257˙048.66
5	INSTALLATION EUROPEENNE DE RAYONNEMENT SYNCHROTRON Organization address address: rue Jules Horowitz 6 city: GRENOBLE postcode: 38043 contact info Titolo: Ms. Nome: Anne Cognome: Talucci Email: send email Telefono: +33 4 76 88 20 12 Fax: +33 4 76 88 28 06	FR (GRENOBLE)	participant	257˙048.66
6	ASTRAZENECA AB Organization address address: Vastra Maelarhamnen city: SODERTAELJE postcode: 151 85 contact info Titolo: Dr. Nome: Margareta Cognome: Ek Email: send email Telefono: 46317065243	SE (SODERTAELJE)	participant	227˙872.04
7	MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. Organization address address: Hofgartenstrasse 8 city: MUENCHEN postcode: 80539 contact info Titolo: Ms. Nome: Sylke Cognome: Schmidt Email: send email Telefono: 496221000000 Fax: 496221000000	DE (MUENCHEN)	participant	223˙168.88
8	UNIVERSITAET HAMBURG Organization address address: EDMUND-SIEMERS-ALLEE 1 city: HAMBURG postcode: 20146 contact info Titolo: Ms. Nome: Linda Cognome: Reams-Behboud Email: send email Telefono: +49 40 42838 4425 Fax: +49 40 42838 6594	DE (HAMBURG)	participant	223˙168.88
9	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: University Offices, Wellington Square city: OXFORD postcode: OX1 2JD contact info Titolo: Ms. Nome: Gill Cognome: Wells Email: send email Telefono: 44186589842 Fax: 441865000000	UK (OXFORD)	participant	166˙283.04
10	MOLECULAR DIMENSIONS LIMITED Organization address address: WILLIE SNALTH ROAD GOODWIN BUSINESS PARK UNIT 6 city: NEWMARKET postcode: CB8 7SQ contact info Titolo: Mr. Nome: Anthony Cognome: Savill Email: send email Telefono: 441639000000 Fax: 441639000000	UK (NEWMARKET)	participant	135˙710.08
11	SWISSCI AG Organization address address: NEUHOFSTRASSE 74 city: NEUHEIM postcode: 6345 contact info Titolo: Dr. Nome: Michael Cognome: Magerstaedt Email: send email Telefono: 41417111101 Fax: 41417401024	CH (NEUHEIM)	participant	69˙457.49

Mappa

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synchrotron nanomem created biology resolution femtosecond x free nano structural micro serial ray community scientific electron developments membrane crystallography lasers training diffraction sources protein

Obiettivo del progetto (Objective)

'Modern structural biology builds upon synergies between lab-bench scale science on the one hand and large scale research infrastructure on the other. NanoMem recognises the transformative opportunities that are created by current X-ray source and detector developments to impact strongly on membrane protein structure, a challenging sub-field of structural biology. We will exploit synchrotron based micro-focus X-ray beams to address challenging diffraction studies from small membrane protein crystals; and embrace the revolutionary possibilities created by X-ray Free Electron Lasers to deliver an entirely new regime of high-resolution serial femtosecond crystallography of membrane proteins. These developments will place heavy demands on motivated and highly-trained talent. The time is ripe for bringing young scientists into the loop. Nanomem will train the nucleus of a new community spread across Europe that widens the access and use of non-conventional methods to capture membrane protein structures at high resolution. Our interdisciplinary and intersectorial research training work programme incorporates membrane protein production, purification and crystallisation, micro and nano-crystal manipulation, micro-focus diffraction at synchrotron sources, nano-focus diffraction at X-ray free electron lasers, serial femtosecond crystallography, software development, drug design, and commercialisation of the most helpful innovations. On-site scientific training of nine ESRs and one ER with seamless industrial participation will be complemented with training in areas such as intellectual property, communication skills and scientific mentoring. The current major European effort in the construction of new brilliant X-ray sources has to be matched by an investment in nurturing the birth of a scientific community for its exploitation, pushing the limits of our understanding of membrane protein structural biology.'