NANOTRIGGER
Triggerable nanomaterials to modulate cell activity
| Coordinatore | CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
Spiacenti, non ci sono informazioni su questo coordinatore. Contattare Fabio per maggiori infomrazioni, grazie. |
| Nazionalità Coordinatore | Portugal [PT] |
| Totale costo | 1˙699˙320 € |
| EC contributo | 1˙699˙320 € |
| Programma | FP7-IDEAS-ERC
Specific programme: "Ideas" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) |
| Code Call | ERC-2012-StG_20111012 |
| Funding Scheme | ERC-SG |
| Anno di inizio | 2012 |
| Periodo (anno-mese-giorno) | 2012-11-01 - 2017-10-31 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
Organization address
address: UNIVERSIDADE DE COIMBRA . contact info |
PT (COIMBRA) | hostInstitution | 1˙699˙320.00 |
| 2 |
CENTRO DE NEUROCIENCIAS E BIOLOGIACELULAR ASSOCIACAO
Organization address
address: UNIVERSIDADE DE COIMBRA . contact info |
PT (COIMBRA) | hostInstitution | 1˙699˙320.00 |
Mappa
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Obiettivo del progetto (Objective)
'The advent of molecular reprogramming and the associated opportunities for personalised and therapeutic medicine requires the development of novel systems for on-demand delivery of reprogramming factors into cells in order to modulate their activity/identity. Such triggerable systems should allow precise control of the timing, duration, magnitude and spatial release of the reprogramming factors. Furthermore, the system should allow this control even in vivo, using non-invasive means. The present project aims at developing triggerable systems able to release efficiently reprogramming factors on demand. The potential of this technology will be tested in two settings: (i) in the reprogramming of somatic cells in vitro, and (ii) in the improvement of hematopoietic stem cell engraftment in vivo, at the bone marrow. The proposed research involves a team formed by engineers, chemists, biologists and is highly multidisciplinary in nature encompassing elements of engineering, chemistry, system biology, stem cell technology and nanomedicine.'