BAGEL

"Bacterial Formation of Glycerol (di)Ether Lipids: Biogeochemical, (paleo)environmental and evolutionary implications"

 Coordinatore UNIVERSITE LYON 1 CLAUDE BERNARD 

 Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43
city: VILLEURBANNE CEDEX
postcode: 69622

contact info
Titolo: Dr.
Nome: Javier
Cognome: Olaiz
Email: send email
Telefono: 33472697600
Fax: 33472697609

 Nazionalità Coordinatore France [FR]
 Totale costo 202˙405 €
 EC contributo 202˙405 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2012-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-09-01   -   2015-08-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITE LYON 1 CLAUDE BERNARD

 Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43
city: VILLEURBANNE CEDEX
postcode: 69622

contact info
Titolo: Dr.
Nome: Javier
Cognome: Olaiz
Email: send email
Telefono: 33472697600
Fax: 33472697609

FR (VILLEURBANNE CEDEX) coordinator 202˙405.80

Mappa


 Word cloud

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prokaryotes    relies    bacteria    dgd    synthesize    combination    microbial    archaea    mesophilic    chemical    isoprenoid    bacterial    marine    glycerol    evolution    ecology    lipid   

 Obiettivo del progetto (Objective)

'The three domains of life on Earth comprise the two groups of prokaryotes Archaea and Bacteria whom distinction notably relies on the chemical composition of cellular membranes. Bacteria generally synthesize phospholipids constituted of non-isoprenoid alkyl chains esterified to glycerol, whereas Archaea synthesize isoprenoid ethers of glycerol. These differences have potential implications in term of ecology and evolution of Bacteria and Archaea and are frequently used as distinguishing marks. Non-isoprenoid diethers of glycerol (non-isoprenoid DGD) constitute an exception to these chemical distinctions as they exhibit an intriguing combination of structural features of Bacteria and Archaea. The physiological role and the mode of formation of these lipids are poorly understood. Remarkably, these compounds have never been observed in mesophilic marine bacteria although they are omnipresent in non-extreme interfaces between the Biosphere and the Geosphere where their origin remains speculative. This multidisciplinary project aims at investigating in detail the first isolate of marine mesophilic sulphate-reducing bacterium able to produce non-isoprenoid DGD, and at comparing it with other (un)related strains. It relies on the combination of lipidomics (analysis of lipid biomarkers) with microbial ecology and microscopy coupled with spectroscopy (bacterial ecophysiology based on ultrastructure). Results will allow specifying the use of DGD as biogeochemical proxy and clarifying the link between living bacterial structures and the observation of microbial signatures within the sedimentary record. It should also shed light on crucial aspects of microbial ecology and on the evolution of lipid biosynthesis in prokaryotes. The project is based on preliminary results obtained by the host. Its relevance is supported by complementary expertise in microbiology and microbial ecology (national collaboration) and is strengthened by outstanding international collaboration.'

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